Conversion of hexadecanoic acid to hexadecenoic acid by rat Δ6-desaturase

Autor: Hervé Guillou, Vincent Rioux, Daniel Catheline, Jean-Noël Thibault, Monique Bouriel, Sophie Jan, Sabine D'Andrea, Philippe Legrand

Publikováno v: Journal of Lipid Research, Vol 44, Iss 3, Pp 450-454 (2003)

A higher content of C16:1 n-10 has recently been reported in the preputial gland of mice with a targeted disruption of the gene encoding stearoyl-CoA desaturase 1 (SCD1−/− mice) when compared with wild-type mice. This result has provided the firs

Externí odkaz: https://doaj.org/article/843d65ca86e844c6929e8c52f1ad4ee6

Myristic acid increases Δ6-desaturase activity in cultured rat hepatocytes

Autor: Hervé Guillou, Philippe Legrand, Stéphanie Daval, Sabine d'Andrea, Sophie Jan, Vincent Rioux, Monique Bouriel

Publikováno v: Reproduction Nutrition Development
Reproduction Nutrition Development, EDP Sciences, 2004, 44 (2), pp.131-140. ⟨10.1051/rnd:2004020⟩

In order to study the effects of saturated fatty acids on ∆6-desaturase activity, rat hepatocytes in primary culture were incubated with lauric (C12:0), myristic (C14:0) or palmitic (C16:0) acids. After optimization, the standard in vitro condition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcccdd226fd5803889ec753fa8843b1e
https://doi.org/10.1051/rnd:2004020

High performance liquid chromatography of fatty acids as naphthacyl derivatives

Autor: Vincent Rioux, Philippe Legrand, Monique Bouriel, Daniel Catheline

Publikováno v: Analusis. 27:186-193

A procedure for the separation of fatty acids, after their derivatization as fatty acid naphthacyl esters, by reverse-phase high performance liquid chromatography is described. A reproducible resolution (50 min), shorter than former HPLC analyses, of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb8a02c83ac51e19cb37491e23f7c243
https://doi.org/10.1051/analusis:1999165

Conversion of hexadecanoic acid to hexadecenoic acid by rat delta 6-desaturase

Autor: Hervé Guillou, Sabine d'Andrea, Philippe Legrand, Monique Bouriel, Vincent Rioux, Jean-Noël Thibault, Sophie Jan, Daniel Catheline

Publikováno v: Journal of Lipid Research
Journal of Lipid Research, American Society for Biochemistry and Molecular Biology, 2003, 44 (3), pp.450-454. ⟨10.1194/jlr.C200019-JLR200⟩
Journal of Lipid Research 3 (44), 450-454. (2003)
Journal of Lipid Research, Vol 44, Iss 3, Pp 450-454 (2003)

A higher content of C16:1 n-10 has recently been reported in the preputial gland of mice with a targeted disruption of the gene encoding stearoyl-CoA desaturase 1 (SCD1-/- mice) when compared with wild-type mice. This result has provided the first ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e949b50a134b88f1f68361b9d5531e6f
https://hal.inrae.fr/hal-02678861/file/69310_20100909100536597_1.pdf

Stearoyl coenzyme A desaturase 1 expression and activity are increased in the liver during iron overload

Autor: Philippe Legrand, Olivier Loréal, Christelle Pigeon, Bruno Turlin, Monique Bouriel, Pierre Brissot, Patricia Leroyer

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. (3):275-284

In humans, hepatic iron overload can lead to hepatocellular carcinoma development. Iron related dysregulation of hepatic genes could play a role in this phenomenon. We previously found that the carbonyl-iron overloaded mouse was a useful model to stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d29045b0b05a31fabc5e3e37218de0