Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Monique Allix"'
Autor:
Christiane Charriaut-Marlangue, Michel Plotkine, Christian Mésenge, Roger R. Boulu, Catherine Verrecchia, Monique Allix
Publikováno v:
European Journal of Pharmacology. 353:53-57
Oxygen free radicals and nitric oxide (NO) have been proposed to be involved in the cascade of injury elicited by traumatic brain injury. However, the mechanism(s) of injury remain to be explored. Since superoxide generation is triggered by traumatic
Publikováno v:
British Journal of Pharmacology. 122:625-630
1. The temporal changes in constitutive NO-synthase (cNOS) and in calcium-independent NO-synthase activities were studied in mice subjected to 2 h of transient focal cerebral ischaemia. The changes in brain nitrites/nitrates (NOx) content were also s
Publikováno v:
British Journal of Pharmacology. 120:160-163
In this study the effect of the dose and administration time of NG-nitro-l-arginine methyl ester (l-NAME), an NO-synthase inhibitor, in a model of transient focal cerebral ischaemia in rats was investigated. Two injections of l-NAME were given, of 1,
Autor:
Isabelle Margaill, Roger G. Boulu, S. Parmentier, Jacques Callebert, Michel Plotkine, Monique Allix
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 16:107-113
The present study investigates the role of N-methyl-D-aspartate (NMDA) receptors in a model of transient focal cerebral ischemia in normotensive rats. The left middle cerebral artery and both common carotid arteries were occluded for 60 min. Prelimin
Publikováno v:
Annals of Nutrition and Metabolism. 39:285-290
Gastric ulcers were induced by immobilization in adult female mice with genetically low (MGL) or high (MGH) blood magnesium levels, obtained by selective breeding at the CSAL-CNRS (Orléans, France). All animals, fed with the same standard diet rich
Autor:
Isabelle Margaill, Michel Plotkine, Monique Allix, Catherine Verrecchia, Christian Mésenge, Roger G. Boulu
Publikováno v:
Journal of pineal research. 25(1)
The pineal hormone melatonin has recently been shown to exert neuroprotective activity in a variety of experimental neuropathologies in which free radicals are involved. This neuroprotective effect has been attributed to the antioxidant properties of
Publikováno v:
Europe PubMed Central
This study investigates the effect of the NO synthase inhibitors, NG-nitro L-arginine methyl ester (L-NAME) and 7-nitro indazole (7-NI), on the neurological deficit 24 h after a moderate closed head injury in mice. Low doses of L-NAME or 7-NI given s
Publikováno v:
European journal of pharmacology. 230(2)
The effects of riluzole, a putative inhibitor of glutamate release, on the histological and neurobehavioral consequences of middle cerebral artery occlusion were tested in Sprague-Dawley rats. Neurobehavioral studies (neurological examination, passiv
Publikováno v:
European journal of pharmacology. 201(1)
The effect of isosorbide dinitrate, a nitrovasodilator known to inhibit platelet function, was examined in a model of electrically induced carotid artery thrombosis in rats. In the dose range of 1-30 mg/kg isosorbide dinitrate, administered orally, s
Autor:
Jean-Philippe Devissaguet, Hatem Fessi, Michel Plotkine, Roger G. Boulu, Monique Allix, Nazih Ammoury
Publikováno v:
The Journal of pharmacy and pharmacology. 42(8)
Nanocapsules, containing indomethacin, were prepared either by interfacial polymerization of isobutylcyanoacrylate monomers or by interfacial deposition of a preformed (DL-lactide) polymer. In-vitro release of indomethacin from nanocapsules was depen