Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Monique Anthony"'
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 10, Pp 1708-1717 (2002)
Niemann-Pick C (NPC) is an autosomal recessive lysosomal lipid storage disease characterized by progressive central nervous system degeneration. In cultured human NPC fibroblasts, LDL-derived cholesterol accumulates in lysosomes and endosomes, LDL-ch
Externí odkaz:
https://doaj.org/article/fb991ee0abf14f9d8b66e90137c45a0b
Autor:
Yanling Huang, Murali Gururajan, Cullen L. Cavallaro, Zhuyin Li, Ashok V. Purandare, Jessica J. Wong, Jenny Xie, Sylwia Stachura, Huadong Sun, Lalgudi S. Harikrishnan, Javed Khan, Brian E. Fink, Carolyn A. Weigelt, Honghe Wan, Peter K. Park, Daniel O'malley, Michele Agler, Cliff Chen, John S. Sack, Donna D. Wei, Zheming Ruan, Melissa Yarde, Heidi L. Perez, Monique Anthony, Virna Borowski, Max Ruzanov
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 35:127778
The discovery of a series of substituted diarylether compounds as retinoic acid related orphan receptor γt (RORγt) agonists is described. Compound 1 was identified from deck mining as a RORγt agonist. Hit-to-lead optimization led to the identifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6bcbeb08e68c5a36002135e73f0931e
https://doi.org/10.1016/j.bmcl.2021.127778
https://doi.org/10.1016/j.bmcl.2021.127778
Autor:
Oren Beske, George Hansen, Martyn Banks, Kristin E. Yates, Michele Agler, Yingjie Zhu, Monique Anthony, Taosheng Chen
Publikováno v:
Expert Review of Molecular Diagnostics. 5:817-829
High-content screening technologies utilize assays that monitor and quantify multiple cellular events. These assays are typically performed on a single cell type with automated microscopy and image analysis. However, in order to better understand the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4df574ddf600c425c69bfad6916d802
https://doi.org/10.1586/14737159.5.5.817
https://doi.org/10.1586/14737159.5.5.817
Autor:
Joseph Tamasi, Jean H.M. Feyen, Jacques Y. Roberge, Xiaodong Wang, Yu Dong, Zhaoqing Wang, R. Michael Lawrence, Margaret M. Prack, Dora M. Schnur, Vanessa Dell, Yalei Liu, Rajasree Golla, Michele Agler, James R. Corte, Ramakrishna Seethala, Monique Anthony, Tianan Fang, John K. Dickson
Publikováno v:
Steroids. 69:201-217
The identification of a new series of selective nonsteroidal progesterone receptor (PR) agonists is reported. Using a high-throughput screening assay based on the measurement of transactivation of a mouse mammary tumor virus promoter-driven luciferas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ffe5a99e07a3272ec5e2b8be155956
https://doi.org/10.1016/j.steroids.2003.12.007
https://doi.org/10.1016/j.steroids.2003.12.007
Autor:
Ronald E. Rose, Craig J. Dowling, Mark I. Cockett, Michael Wichroski, Lauren E. Barber, Daniel J. Tenney, Michele Agler, Samuel Gerritz, Brett R. Beno, Betsy J. Eggers, Charles E. Mazzucco, John E. Leet, Carl J. Baldick, Kevin A. Pokornowski, Monique Anthony, Jie Fang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e42609 (2012)
PLoS ONE, Vol 7, Iss 8, p e42609 (2012)
The recent development of a Hepatitis C virus (HCV) infectious virus cell culture model system has facilitated the development of whole-virus screening assays which can be used to interrogate the entire virus life cycle. Here, we describe the develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02428d4ee430a5b86e293509ef9a40b2
http://europepmc.org/articles/PMC3412796
http://europepmc.org/articles/PMC3412796
Autor:
Edward W. Petrillo, Jeremy Stewart, John J. Herbst, Monique Anthony, David Connors, Taosheng Chen, Martyn Banks, Michele Agler
Publikováno v:
Assay and drug development technologies. 7(3)
In order to identify potential cytochrome P-450 3A4 (drug-metabolizing enzyme) inducers at an early stage of the drug discovery process, a cell-based transactivation high-throughput luciferase reporter assay for the human pregnane X receptor (PXR) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b13963399e82d3d7c77e8133e7e997
https://pubmed.ncbi.nlm.nih.gov/19530896
https://pubmed.ncbi.nlm.nih.gov/19530896
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 10, Pp 1708-1717 (2002)
Niemann-Pick C (NPC) is an autosomal recessive lysosomal lipid storage disease characterized by progressive central nervous system degeneration. In cultured human NPC fibroblasts, LDL-derived cholesterol accumulates in lysosomes and endosomes, LDL-ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f99816a0b21a660a326ddcf3f08d1db
https://pubmed.ncbi.nlm.nih.gov/12364555
https://pubmed.ncbi.nlm.nih.gov/12364555
Autor:
John Herbst, Monique Anthony, Jeremy Stewart, David Connors, Taosheng Chen, Martyn Banks, Edward W. Petrillo, Michele Agler
Publikováno v:
Assay & Drug Development Technologies; Jun2009, Vol. 7 Issue 3, p294-303, 10p