Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Monique, Wasunna"'
Autor:
Luka Verrest, Séverine Monnerat, Ahmed M Musa, Jane Mbui, Eltahir A G Khalil, Joseph Olobo, Monique Wasunna, Wan-Yu Chu, Alwin D R Huitema, Henk D F H Schallig, Fabiana Alves, Thomas P C Dorlo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 4, p e0012078 (2024)
BackgroundWith the current treatment options for visceral leishmaniasis (VL), recrudescence of the parasite is seen in a proportion of patients. Understanding parasite dynamics is crucial to improving treatment efficacy and predicting patient relapse
Externí odkaz:
https://doaj.org/article/f159d249ee9d4df7a72474193af8e333
Autor:
Brima Musa Younis, Ahmed Mudawi Musa, Séverine Monnerat, Mohammed Abdelrahim Saeed, Eltahir Awad Gasim Khalil, Anas Elbashir Ahmed, Mujahid Ahmed Ali, Ali Noureldin, Gina Muthoni Ouattara, Godfrey M Nyakaya, Samuel Teshome, Truphosa Omollo, Michael Ochieng, Thaddaeus Egondi, Mildred Mmbone, Wan-Yu Chu, Thomas P C Dorlo, Eduard E Zijlstra, Monique Wasunna, Jorge Alvar, Fabiana Alves
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011780 (2023)
BackgroundTreatment for post-kala-azar dermal leishmaniasis (PKDL) in Sudan is currently recommended only for patients with persistent or severe disease, mainly because of the limitations of current therapies, namely toxicity and long hospitalization
Externí odkaz:
https://doaj.org/article/8e80fbd2c0f14737b661e76f2ce1ecf5
Autor:
Monique Couderc-Pétry, Elisabeth Eléfant, Monique Wasunna, Alwyn Mwinga, Nilima A Kshirsagar, Nathalie Strub-Wourgaft
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008140 (2020)
Externí odkaz:
https://doaj.org/article/1ac24dda01ef4cb18f8c3fd94a621784
Autor:
Ahmed M, Musa, Jane, Mbui, Rezika, Mohammed, Joseph, Olobo, Koert, Ritmeijer, Gabriel, Alcoba, Gina, Muthoni Ouattara, Thaddaeus, Egondi, Prossy, Nakanwagi, Truphosa, Omollo, Monique, Wasunna, Luka, Verrest, Thomas P C, Dorlo, Brima, Musa Younis, Ali, Nour, Elmukashfi, Taha Ahmed Elmukashfi, Ahmed, Ismail Omer Haroun, Eltahir A G, Khalil, Simon, Njenga, Helina, Fikre, Tigist, Mekonnen, Dagnew, Mersha, Kasaye, Sisay, Patrick, Sagaki, Jorge, Alvar, Alexandra, Solomos, Fabiana, Alves
Publikováno v:
Clinical Infectious Diseases. 76:e1177-e1185
Background This study aimed to determine whether paromomycin plus miltefosine (PM/MF) is noninferior to sodium stibogluconate plus paromomycin (SSG/PM) for treatment of primary visceral leishmaniasis in eastern Africa. Methods An open-label, phase 3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe571622e1e72782a5232658c426563
https://doi.org/10.1093/cid/ciac643
https://doi.org/10.1093/cid/ciac643
Autor:
Ermias Diro, Tansy Edwards, Koert Ritmeijer, Helina Fikre, Charles Abongomera, Aderajew Kibret, Clélia Bardonneau, Peninah Soipei, Brian Mutinda, Raymond Omollo, Johan van Griensven, Eduard E Zijlstra, Monique Wasunna, Fabiana Alves, Jorge Alvar, Asrat Hailu, Neal Alexander, Séverine Blesson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007132 (2019)
BACKGROUND:The long-term treatment outcome of visceral leishmaniasis (VL) patients with HIV co-infection is complicated by a high rate of relapse, especially when the CD4 count is low. Although use of secondary prophylaxis is recommended, it is not r
Externí odkaz:
https://doaj.org/article/d7d41278dcee4a21a819af1de360a1f6
Autor:
Ermias Diro, Severine Blesson, Tansy Edwards, Koert Ritmeijer, Helina Fikre, Henok Admassu, Aderajew Kibret, Sally J Ellis, Clelia Bardonneau, Eduard E Zijlstra, Peninah Soipei, Brian Mutinda, Raymond Omollo, Robert Kimutai, Gabriel Omwalo, Monique Wasunna, Fentahun Tadesse, Fabiana Alves, Nathalie Strub-Wourgaft, Asrat Hailu, Neal Alexander, Jorge Alvar
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 1, p e0006988 (2019)
BackgroundVisceral leishmaniasis (VL) in human immunodeficiency virus (HIV) co-infected patients requires special case management. AmBisome monotherapy at 40 mg/kg is recommended by the World Health Organization. The objective of the study was to ass
Externí odkaz:
https://doaj.org/article/93a200defb1d4695aaaaf1898f7cb459
Autor:
Anke E. Kip, Monique Wasunna, Fabiana Alves, Jan H. M. Schellens, Jos H. Beijnen, Ahmed M. Musa, Eltahir A. G. Khalil, Thomas P. C. Dorlo
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
The Leishmania parasite resides and replicates within host macrophages during visceral leishmaniasis (VL). This study aimed to evaluate neopterin, a marker of macrophage activation, as possible pharmacodynamic biomarker to monitor VL treatment respon
Externí odkaz:
https://doaj.org/article/57f7980ee73f4e9d8eb36db984b24338
Autor:
Thomas P. C. Dorlo, Jaya Chakravarty, Eltahir A G Khalil, Ahmed Eleojo Musa, Yalemtsehay Mekonnen, Madhukar Rai, Luka Verrest, Rashid Aman, Zewdu Hurissa, Workagegnehu Hailu, Samson Tesfaye, Jos H. Beijnen, Monique Wasunna, Gilbert Kokwaro, Smita Kshirsagar, Asrat Hailu, Mahmoud Mudawi, Eyasu Makonnen, Alwin D. R. Huitema, Fabiana Alves, Brima M. Younis, Shyam Sundar
Publikováno v:
Clinical Pharmacokinetics
Introduction Intramuscular paromomycin monotherapy to treat visceral leishmaniasis (VL) has been shown to be effective for Indian patients, while a similar regimen resulted in lower efficacy in Eastern Africa, which could be related to differences in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f64d996bde4fb2285008bb1aa80e38
https://doi.org/10.1007/s40262-021-01036-8
https://doi.org/10.1007/s40262-021-01036-8
Autor:
Jacob T Bush, Monique Wasunna, Fabiana Alves, Jorge Alvar, Piero L Olliaro, Michael Otieno, Carol Hopkins Sibley, Nathalie Strub Wourgaft, Philippe J Guerin
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 9, p e0005781 (2017)
There are an estimated 200,000 to 400,000 cases of visceral leishmaniasis (VL) annually. A variety of factors are taken into account when considering the best therapeutic options to cure a patient and reduce the risk of resistance, including geograph
Externí odkaz:
https://doaj.org/article/0c9877163c4a4391b8df04218b9eb8c7
Autor:
Peninah Menza, Robert Kimutai, Anke E. Kip, Fabiana Alves, Monique Wasunna, Ermias Diro, Bewketu Mengesha, Asrat Hailu, Jos H. Beijnen, Thomas P. C. Dorlo, Séverine Blesson
Publikováno v:
Journal of Antimicrobial Chemotherapy
Background Despite high HIV co-infection prevalence in Ethiopian visceral leishmaniasis (VL) patients, the adequacy of antileishmanial drug exposure in this population and effect of HIV-VL co-morbidity on pharmacokinetics of antileishmanial and antir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6248558d8161bb07c35f94672448b3c1
http://europepmc.org/articles/PMC8050768
http://europepmc.org/articles/PMC8050768