Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Monique, Philippe"'
Autor:
Oumou Maïga, Dominique Pidard, Larissa Kotelevets, Eric Chastre, Monique Philippe, Samira Benadda, Laurence Walch, Roger Vranckx
Publikováno v:
FEBS Journal. 278:2655-2665
Human disc-large homolog (hDlg), also known as synapse-associated protein 97, is a scaffold protein, a member of the membrane-associated guanylate kinase family, implicated in neuronal synapses and epithelial-epithelial cell junctions whose expressio
Autor:
Jean-Baptiste Michel, Ayman Al Haj Zen, Monique Philippe, Paulo Sampaio Gutierrez, Luciano de Figueiredo Borges, Anne Leclercq, Guillaume Jondeau, Olivier Meilhac, Brigitte Franc, Ziad Touat
Publikováno v:
Human Pathology. 40:306-313
Histopathological alterations in human aneurysms and dissections of the thoracic ascending aorta include areas of mucoid degeneration within the medial layer, colocalized with areas of cell disappearance and disruption of extracellular matrix elastic
Autor:
Delphine Gomez, Jean-Baptiste Michel, Ayman Al Haj Zen, Guillaume Jondeau, Luciano de Figueiredo Borges, Roger Vranckx, Paulo Sampaio Gutierrez, Monique Philippe
Publikováno v:
The Journal of Pathology. 218:131-142
Common features such as elastic fibre destruction, mucoid accumulation, and smooth muscle cell apoptosis are co-localized in aneurysms of the ascending aorta of various aetiologies. Recent experimental studies reported an activation of TGF-beta in an
Autor:
Olivier Meilhac, Monique Philippe, Xavier Houard, Liliane Louedec, Ziad Touat, Patrick Rossignol, Véronique Ollivier, Uriel Sebbag, Jean-Baptiste Michel
Publikováno v:
Cardiovascular Research; Vol 82
Cardiovascular Research
Cardiovascular Research
Aims Neutrophils/platelet interactions are involved in abdominal aortic aneurysm (AAA). The intraluminal thrombus (ILT) is a human model of platelet/neutrophil interactions. The present study focused on mediators involved in neutrophil recruitment in
Autor:
El Mostafa Mtairag, Walter Gonzalez, Laurent J. Feldman, Mikael Mazighi, Jean-Baptiste Michel, Monique Philippe, Anne Pellé, Dominique Hénin
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 287:H866-H871
The anti-inflammatory cytokine IL-10 inhibits intimal hyperplasia after stent implantation via a powerful inactivation of monocytes. We tested the hypothesis that IL-10 may also inhibit vascular smooth muscle cell (SMC) activation via the inhibition
Autor:
M. Challah, Maria E. Pueyo, Michel Marre, Marie-Paule Jacob, Liliane Louedec, Roger Gaertner, Monique Philippe, Jean-Baptiste Michel, Dominique Gauguier
Publikováno v:
Diabetes. 53:1111-1118
Genetic background appears to modulate the development of diabetic vascular complications. In particular, polymorphisms in the ACE gene have been associated with diabetic nephropathy and, in some studies, macrovascular complications. However, the lin
Autor:
Antonino Nicoletti, Delphine Lepailleur-Enouf, Monique Philippe, Roger Gaertner, Walter Gonzalez, Chantal Mandet, Jean-Jacques Mercadier, Jean-Baptiste Michel
Publikováno v:
European Journal of Heart Failure. 5:435-442
Background: Pulmonary endothelium is an early upstream hemodynamic target of left ventricular dysfunction. Interleukin 6 (IL-6) is a pro-inflammatory cytokine reported to increase in congestive heart failure (CHF) patients. Aims: We sought to determi
Autor:
Marie-Claude Guillin, Patrick Rossignol, Benjamin Richard, Jean-Baptiste Michel, Marie-Christine Bouton, Martine Jandrot-Perrus, Monique Philippe
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 23:142-147
Objective— Protease-nexin 1 (PN-1) belongs to the serpin superfamily and behaves as a specific thrombin inhibitor in the pericellular environment. Little is known about PN-1 expression and its regulation in the vascular system. In this study, we ex
Autor:
Paul Mulder, Monique Philippe, Delphine Lepailleur-Enouf, Jean-Paul Henry, Liliane Louedec, Giorgia Egidy, Jean-Baptiste Michel
Publikováno v:
Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2001, 49 (2), pp.330-9. ⟨10.1016/s0008-6363(00)00264-9⟩
Cardiovascular Research, Oxford University Press (OUP), 2001, 49 (2), pp.330-9. ⟨10.1016/s0008-6363(00)00264-9⟩
International audience; Objectives: Endothelin-1 (ET-1), plays an important role in the pathophysiology of CHF and the pulmonary endothelium is an early hemodynamic target in diastolic left ventricular dysfunction. Therefore we hypothesized that the
Angiotensin I-Converting Enzyme Genotype Influences Arterial Response to Injury in Normotensive Rats
Autor:
Jean-Paul Vilaine, Antoine Ribadeau-Dumas, Florent Soubrier, Bruno Giraudeau, Eric Villard, Jean-Baptiste Michel, M. Challah, Philip Janiak, Monique Philippe
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 18:235-243
Abstract —Two normotensive strains of rat, the Lou and Brown Norway (BN) strains, have contrasting levels of plasma angiotensin-converting enzyme (ACE). To investigate the degree of genetic determination of ACE expression, a polymorphic marker of t