Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Monika Ziminska"'
1
Akademický článek
Improving the Intercellular Uptake and Osteogenic Potency of Calcium Phosphate via Nanocomplexation with the RALA Peptide
Autor: Michelle O’Doherty, Eoghan J. Mulholland, Philip Chambers, Sreekanth Pentlavalli, Monika Ziminska, Marine J. Chalanqui, Hannah M. Pauly, Binulal N. Sathy, Tammy H. Donahue, Daniel J. Kelly, Nicholas Dunne, Helen O. McCarthy
Publikováno v: Nanomaterials, Vol 10, Iss 12, p 2442 (2020)
Calcium phosphate-base materials (e.g., alpha tri-calcium phosphate (α–TCP)) have been shown to promote osteogenic differentiation of stem/progenitor cells, enhance osteoblast osteogenic activity and mediate in vivo bone tissue formation. However,
Externí odkaz: https://doaj.org/article/a3ac06e131d04e7eb1cf5e4b5325fecc
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2
Akademický článek
Synthesis and Evaluation of a Thermoresponsive Degradable Chitosan-Grafted PNIPAAm Hydrogel as a 'Smart' Gene Delivery System
Autor: Monika Ziminska, Jordan J. Wilson, Emma McErlean, Nicholas Dunne, Helen O. McCarthy
Publikováno v: Materials, Vol 13, Iss 11, p 2530 (2020)
Thermoresponsive hydrogels demonstrate tremendous potential as sustained drug delivery systems. However, progress has been limited as formulation of a stable biodegradable thermosensitive hydrogel remains a significant challenge. In this study, free
Externí odkaz: https://doaj.org/article/4ade46979d4544688c1efd00589a490d
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4
Rational design and characterisation of a linear cell penetrating peptide for non-viral gene delivery
Autor: Eoghan J. Mulholland, Monika Ziminska, Tracy Robson, Grace Cole, Vicky L. Kett, Helen O. McCarthy, Emma M. McErlean, Nicholas Dunne, Cian M. McCrudden, Niamh E. Buckley, John W. McBride, Stephen P. Loughran
Publikováno v: McErlean, E M, Ziminska, M, McCrudden, C M, McBride, J W, Loughran, S P, Cole, G, Mulholland, E J, Kett, V, Buckley, N E, Robson, T, Dunne, N J & McCarthy, H O 2020, ' Rational design and characterisation of a linear cell penetrating peptide for non-viral gene delivery ', Journal of Controlled Release, vol. 330, pp. 1288 . https://doi.org/10.1016/j.jconrel.2020.11.037
The design of a non-viral gene delivery system that can release a functional nucleic acid at the intracellular destination site is an exciting but also challenging proposition. The ideal gene delivery vector must be non-toxic, non-immunogenic, overco
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f03a6e561e7b2be5887b475b411cf9e
https://doi.org/10.1016/j.jconrel.2020.11.037
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5
Advancing bone tissue engineering one layer at a time: a layer-by-layer assembly approach to 3D bone scaffold materials
Autor: MohammadAli Sahebalzamani, Monika Ziminska, Helen O. McCarthy, Tanya J. Levingstone, Nicholas J. Dunne, Andrew R. Hamilton
Publikováno v: Sahebalzamani, M, Ziminska, M, McCarthy, H O, Levingstone, T J, Dunne, N J & Hamilton, A R 2022, ' Advancing bone tissue engineering one layer at a time: a layer-by-layer assembly approach to 3D bone scaffold materials ', Biomaterials Science . https://doi.org/10.1039/d1bm01756j
The layer-by-layer (LbL) assembly technique has shown excellent potential in tissue engineering applications. The technique is mainly based on electrostatic attraction and involves the sequential adsorption of oppositely charged electrolyte complexes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae5948dba38b750d068b560d55a8434
https://pure.qub.ac.uk/en/publications/d069e10a-9d39-46e6-b33a-51403f4d0ec8
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6
Synthesis and Evaluation of a Thermoresponsive Degradable Chitosan-Grafted PNIPAAm Hydrogel as a 'Smart' Gene Delivery System
Autor: Emma M. McErlean, Nicholas Dunne, Helen O. McCarthy, Monika Ziminska, Jordan J. Wilson
Publikováno v: Ziminska, M, Wilson, J J, McErlean, E, Dunne, N & McCarthy, H O 2020, ' Synthesis and Evaluation of a Thermoresponsive Degradable Chitosan-Grafted PNIPAAm Hydrogel as a “Smart” Gene Delivery System ', Materials, vol. 13, no. 11, 2530 . https://doi.org/10.3390/ma13112530
Materials, Vol 13, Iss 2530, p 2530 (2020)
Materials
Volume 13
Issue 11
Thermoresponsive hydrogels demonstrate tremendous potential as sustained drug delivery systems. However, progress has been limited as formulation of a stable biodegradable thermosensitive hydrogel remains a significant challenge. In this study, free
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559ba74651c64808acf9babb9be27ab8
https://pure.qub.ac.uk/en/publications/synthesis-and-evaluation-of-a-thermoresponsive-degradable-chitosangrafted-pnipaam-hydrogel-as-a-smart-gene-delivery-system(8041cd27-17a4-4d47-ae43-0842ae5bcf78).html
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7
Nanocomposite-coated porous templates for engineered bone scaffolds: A parametric study of layer-by-layer assembly conditions
Autor: Marine Chalanqui, Monika Ziminska, Andrew Hamilton, Philip Chambers, Helen O. McCarthy, Jonathan Acheson, Nicholas Dunne
Using the layer-by-layer (LbL) assembly technique to deposit mechanically reinforcing coatings onto porous templates is a route for fabricating engineered bone scaffold materials with a combination of high porosity, strength, and stiffness. LbL assem
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be10f88151fcbde6ae46cad2d0bfbc0
https://eprints.soton.ac.uk/433483/
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8
Nanoscale Hybrid Coating Enables Multifunctional Tissue Scaffold for Potential Multimodal Therapeutic Applications
Autor: Nan Jiang, Songsong Zhu, Andrew Hamilton, Colin P. McCoy, Gianluca Sarri, Jessica Moore, Yubao Li, Cormac Rafferty, Monika Ziminska, Li Zhang, Dan Sun, Zhijun Guo
Publikováno v: Guo, Z, Jiang, N, Moore, J, McCoy, C, Ziminska, M, Rafferty, C, Sarri, G, Hamilton, A, Li, Y, Zhang, L, Zhu, S & Sun, D 2019, ' Nanoscale Hybrid Coating Enables Multifunctional Tissue Scaffold for Potential Multimodal Therapeutic Applications ', ACS Applied Materials and Interfaces, vol. 11, no. 30, pp. 27269 . https://doi.org/10.1021/acsami.9b04278
Through a nature-inspired layer-by-layer assembly process, we developed a unique multifunctional tissue scaffold that consists of porous polyurethane substrate and nanoscale chitosan/graphene oxide hybrid coating. Alternative layers of drug-laden chi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e315813418c51ee45210f736731d93
https://pubmed.ncbi.nlm.nih.gov/31260238
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9
Tissue Scaffolds with Nanoscale Hybrid Coating Shining New Lights on Multi-Modal Bone Targeted Therapeutics
Autor: Colin P. McCoy, Jessica Moore, Li Zhang, Jiang N, Monika Ziminska, Zhijun Guo, Li Y, Gianluca Sarri, Cormac Rafferty, Sun d, Andrew Hamilton, Songsong Zhu
The challenging post-surgery management of bone metastasis sees the needs for multi-functional bone scaffolds that offer multi-modal therapeutic functions. Through a nature-inspired layer-by-layer assembly process, we developed a unique multi-functio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285cbb9066c969317de4847cb71551e7
https://doi.org/10.26434/chemrxiv.7836584.v1
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10
Customization of mechanical properties and porosity of bone tissue scaffold materials via Layer-by-Layer assembly of polymer-nanocomposite coatings
Autor: Monika Ziminska, Nicholas Dunne, Andrew Hamilton
Publikováno v: MRS Proceedings. 1793:67-72
The aim of this preliminary study was to adapt Layer-by-Layer (LbL) assembly to fabricate nanocomposite coatings onto open-cell porous structures, enabling customization of mechanical properties and porosity to obtain materials suitable for bone tiss
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::725bb5f0b06922c94a455a78383f3720
https://doi.org/10.1557/opl.2015.827
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