Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Monika Záhorszká"'
Autor:
Amit K. Dutta, Eira Choudhary, Xuan Wang, Monika Záhorszka, Martin Forbak, Philipp Lohner, Henning J. Jessen, Nisheeth Agarwal, Jana Korduláková, Claudia Jessen-Trefzer
Publikováno v:
ACS Central Science, Vol 5, Iss 4, Pp 644-650 (2019)
Externí odkaz:
https://doaj.org/article/9874e78214ad40049b4868a9d90a921b
Autor:
Maxime Mistretta, Mena Cimino, Pascal Campagne, Stevenn Volant, Etienne Kornobis, Olivier Hebert, Christophe Rochais, Patrick Dallemagne, Cédric Lecoutey, Camille Tisnerat, Alban Lepailleur, Yann Ayotte, Steven R. LaPlante, Nicolas Gangneux, Monika Záhorszká, Jana Korduláková, Sophie Vichier-Guerre, Frédéric Bonhomme, Laura Pokorny, Marvin Albert, Jean-Yves Tinevez, Giulia Manina
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Drug-recalcitrant infections are a leading global-health concern. Bacterial cells benefit from phenotypic variation, which can suggest effective antimicrobial strategies. However, probing phenotypic variation entails spatiotemporal analysis
Externí odkaz:
https://doaj.org/article/fa9c75f3b4af4a52a3bae94cff9e5192
Autor:
Elena G. Salina, Umberto Postiglione, Laurent R. Chiarelli, Deborah Recchia, Monika Záhorszká, Alexander Lepioshkin, Natalia Monakhova, Adrian Pál, Alessio Porta, Giuseppe Zanoni, Jana Korduláková, Elena Kazakova, Davide Sassera, Maria Rosalia Pasca, Vadim Makarov, Giulia Degiacomi
Publikováno v:
mSphere, Vol 7, Iss 6 (2022)
ABSTRACT Tuberculosis (TB) still poses a global menace as one of the deadliest infectious diseases. A quarter of the human population is indeed latently infected with Mycobacterium tuberculosis. People with latent infection have a 5 to 10% lifetime r
Externí odkaz:
https://doaj.org/article/df59359de4744e088c1593f4deded2ce
Autor:
Léo Faïon, Kamel Djaout, Catalin Pintiala, Catherine Piveteau, Florence Leroux, Alexandre Biela, Stéphanie Slupek, Rudy Antoine, Monika Záhorszká, Francois-Xavier Cantrelle, Xavier Hanoulle, Jana Korduláková, Benoit Deprez, Nicolas Willand, Alain R. Baulard, Marion Flipo
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 335 (2023)
Mycobacterium tuberculosis, the pathogen that causes tuberculosis, is responsible for the death of 1.5 million people each year and the number of bacteria resistant to the standard regimen is constantly increasing. This highlights the need to discove
Externí odkaz:
https://doaj.org/article/8f8af7ff2c8049dca93bfab59dd0da06
Autor:
Maxime Mistretta, Mena Cimino, Pascal Campagne, Stevenn Volant, Etienne Kornobis, Olivier Hebert, Christophe Rochais, Patrick Dallemagne, Cédric Lecoutey, Camille Tisnerat, Alban Lepailleur, Yann Ayotte, Steven R. LaPlante, Nicolas Gangneux, Monika Záhorszká, Jana Korduláková, Sophie Vichier-Guerre, Frédéric Bonhomme, Laura Pokorny, Marvin Albert, Jean-Yves Tinevez, Giulia Manina
Drug-recalcitrant infections are a leading global-health concern. Bacterial cells benefit from phenotypic variation, which can suggest effective anti-microbial strategies. However, probing phenotypic variation entails spatiotemporal analysis of indiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::341d224a1ebe6ec3997b591329728341
https://doi.org/10.1101/2023.03.31.535085
https://doi.org/10.1101/2023.03.31.535085
Autor:
Monika Záhorszká, Xuan Wang, Philipp Lohner, Amit K. Dutta, Jana Korduláková, Eira Choudhary, Martin Forbak, Henning J. Jessen, Claudia Jessen-Trefzer, Nisheeth Agarwal
Publikováno v:
ACS Central Science, Vol 5, Iss 4, Pp 644-650 (2019)
[Image: see text] Trehalose is a natural glucose-derived disaccharide found in the cell wall of mycobacteria. It enters the mycobacterial cell through a highly specific trehalose transporter system. Subsequently, trehalose is equipped with mycolic ac
Autor:
Antonio Peixoto, Monika Záhorszká, Jana Korduláková, Mathieu Danel, Fernanda Goncalves, Elodie Vega, Asma Farjallah, Maria Rosalia Pasca, Mary Jackson, Giulia Degiacomi, Laurent R. Chiarelli, Cendrine Seguin, Martin Forbak, Christian Lherbet, Stefan Chassaing, Chantal Carayon, Souhir Abid, Marco Fumagalli, Anna E. Grzegorzewicz
Publikováno v:
ACS Infectious Diseases
ACS Infectious Diseases, American Chemical Society, 2021, 7 (3), pp.552-565. ⟨10.1021/acsinfecdis.0c00325⟩
ACS Infectious Diseases, 2021, 7 (3), pp.552-565. ⟨10.1021/acsinfecdis.0c00325⟩
ACS Infectious Diseases, American Chemical Society, 2021, 7 (3), pp.552-565. ⟨10.1021/acsinfecdis.0c00325⟩
ACS Infectious Diseases, 2021, 7 (3), pp.552-565. ⟨10.1021/acsinfecdis.0c00325⟩
International audience; A novel coumarin-based molecule, designed as a fluorescent surrogate of a thiacetazone-derived antitubercular agent, was quickly and easily synthesized from readily available starting materials. This small molecule, coined Cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5b5cd98cba63d79872ca55f29014c7
https://hal.archives-ouvertes.fr/hal-03209886/document
https://hal.archives-ouvertes.fr/hal-03209886/document
Autor:
Asma, Farjallah, Laurent R, Chiarelli, Martin, Forbak, Giulia, Degiacomi, Mathieu, Danel, Fernanda, Goncalves, Chantal, Carayon, Cendrine, Seguin, Marco, Fumagalli, Monika, Záhorszká, Elodie, Vega, Souhir, Abid, Anna, Grzegorzewicz, Mary, Jackson, Antonio, Peixoto, Jana, Korduláková, Maria Rosalia, Pasca, Christian, Lherbet, Stefan, Chassaing
Publikováno v:
ACS Infect Dis
A novel coumarin-based molecule, designed as a fluorescent surrogate of a thiacetazone-derived antitubercular agent, was quickly and easily synthesized from readily available starting materials. This small molecule, coined as Coum-TAC, exhibited a co
Autor:
Chris Abell, Anthony G. Coyne, Tom L. Blundell, Monika Záhorszká, Vitor Mendes, Jana Korduláková, David M. Dias, Mohamad Sabbah, Katarína Mikušová, Robert G. Vistal
Publikováno v:
Journal of Medicinal Chemistry
Tuberculosis (TB) remains a leading cause of mortality amongst infectious diseases worldwide. InhA, an enoyl ACP-reductase, has been the focus of numerous drug discovery efforts as this is the target of the first line pro-drug isoniazid. However, wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d69f51146b0f675f0e65cd93ee3c0ee
https://www.repository.cam.ac.uk/handle/1810/304143
https://www.repository.cam.ac.uk/handle/1810/304143
Autor:
David M. Dias, Chris Abell, Robert G. Vistal, Tom L. Blundell, Mohamad Sabbah, Vitor Mendes, Katarína Mikušová, Monika Záhorszká, Jana Korduláková, Anthony G. Coyne
Publikováno v:
Journal of Medicinal Chemistry
Tuberculosis (TB) remains a leading cause of mortality among infectious diseases worldwide. InhA has been the focus of numerous drug discovery efforts as this is the target of the first line pro-drug isoniazid. However, with resistance to this drug b