Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Monika Witusik"'
Autor:
Joanna Wasiak, Pola Głowacka, Agnieszka Pudlarz, Adam M. Pieczonka, Katarzyna Dzitko, Janusz Szemraj, Monika Witusik-Perkowska
Publikováno v:
Molecules, Vol 29, Iss 10, p 2292 (2024)
Breast cancer is associated with high mortality and morbidity rates. As about 20–30% of patients exhibiting ER-positive phenotype are resistant to hormonal treatment with the standard drug tamoxifen, finding new therapies is a necessity. Postbiotic
Externí odkaz:
https://doaj.org/article/80dda73140e74232bd67a2b8ac46343b
Autor:
Monika Witusik-Perkowska, Pola Głowacka, Adam M. Pieczonka, Ewa Świderska, Agnieszka Pudlarz, Michał Rachwalski, Julia Szymańska, Magdalena Zakrzewska, Dariusz J. Jaskólski, Janusz Szemraj
Publikováno v:
Cells, Vol 12, Iss 14, p 1906 (2023)
Tumor therapy escape due to undesired side effects induced by treatment, such as prosurvival autophagy or cellular senescence, is one of the key mechanisms of resistance that eventually leads to tumor dormancy and recurrence. Glioblastoma is the most
Externí odkaz:
https://doaj.org/article/d56baa2b90c24caaaa95650aa5ded912
Autor:
Michał Bieńkowski, Sylwester Piaskowski, Ewelina Stoczyńska-Fidelus, Małgorzata Szybka, Mateusz Banaszczyk, Monika Witusik-Perkowska, Emilia Jesień-Lewandowicz, Dariusz J Jaskólski, Anna Radomiak-Załuska, Dorota Jesionek-Kupnicka, Beata Sikorska, Wielisław Papierz, Piotr Rieske, Paweł P Liberski
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65444 (2013)
Glioblastoma is a highly aggressive tumour of the central nervous system, characterised by poor prognosis irrespective of the applied treatment. The aim of our study was to analyse whether the molecular markers of glioblastoma (i.e. TP53 and IDH1 mut
Externí odkaz:
https://doaj.org/article/4701ffcbbfd744298db6f7d4fb280757
Autor:
Dariusz J. Jaskólski, Magdalena Zakrzewska, Monika Witusik-Perkowska, Pawel P. Liberski, Janusz Szemraj
Publikováno v:
OncoTargets and Therapy. 12:3905-3918
Purpose: The in vitro environment can influence not only the molecular background of glioblastoma drug-resistance and treatment efficiency, but also the mechanisms and pathways of cell death. Both crucial molecular pathways and the deregulation of mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdbf239f4dddc3e755d85b714d0f1583
https://doi.org/10.2147/ott.s190601
https://doi.org/10.2147/ott.s190601
Publikováno v:
Cellular and molecular neurobiology. 42(4)
The tumor resistance of glioblastoma cells in vivo is thought to be enhanced by their heterogeneity and plasticity, which are extremely difficult to curb in vitro. The external microenvironment shapes the molecular profile of tumor culture models, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1dcb49ed93748a1f610a1b707a86cc5
https://pubmed.ncbi.nlm.nih.gov/33245508
https://pubmed.ncbi.nlm.nih.gov/33245508
Autor:
Beata Sikorska, Joanna Kordacka, Pawel P. Liberski, Joanna Taha, Krzysztof Zakrzewski, Magdalena Zakrzewska, Monika Witusik-Perkowska, Renata Gruszka
Publikováno v:
American journal of medical genetics. Part A. 179(8)
Encephalocraniocutaneous lipomatosis (ECCL) is a rare neurocutaneous disorder, with only about 100 cases reported worldwide. It is characterized by congenital lesions of the eye, skin, and central nervous system. Only recently, potential causative FG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f026aa9b1c4d6211ceb736c035030a88
https://pubmed.ncbi.nlm.nih.gov/31173478
https://pubmed.ncbi.nlm.nih.gov/31173478
Autor:
Anna Janas, Emilia Zgórzyńska, Barbara Dziedzic, Anna Walczewska, Monika Witusik-Perkowska, Anita Wierzbicka-Ferszt, Anna Zwolinska
Publikováno v:
Archives of Oral Biology. 60:144-153
Objective The oxidative burst of the host cells associated with bacterial pathogen infection contributes to the destruction of periodontal tissue. The present study investigates the effect of docosahexaenoic acid (DHA) on human gingival fibroblast (H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7455e4d2568708e08a631612a6378aba
https://doi.org/10.1016/j.archoralbio.2014.09.009
https://doi.org/10.1016/j.archoralbio.2014.09.009
Autor:
Wielisław Papierz, Magdalena Zakrzewska, Monika Witusik-Perkowska, Beata Sikorska, Dariusz J. Jaskólski, Pawel P. Liberski, Janusz Szemraj
Publikováno v:
Bioscience Reports
Resistance to cancer drugs is a complex phenomenon which could be influenced by in vitro conditions. However, tumour-derived cell cultures are routinely used for studies related to mechanisms of drug responsiveness or the search for new therapeutic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1a9bccd6deccccea12029302ed73c9
https://doi.org/10.1042/bsr20170058
https://doi.org/10.1042/bsr20170058
Autor:
Izabela Zawlik, Tomasz Sobów, Pawel P. Liberski, Krystyna Hulas-Bigoszewska, Beata Pepłońska, Monika Sieruta, Maria Barcikowska, Elizabeth H. Corder, Maria Styczyńska, Sylwia M. Gresner, Monika Witusik, Ewa Golanska
Publikováno v:
Journal of Alzheimer's Disease. 17:359-368
We studied eight polymorphisms within APOE, PRNP, PRND, and CYP46 genes in 213 Polish late-onset patients with Alzheimer's disease (AD) and 171 non-demented elderly controls. A latent classification approach, grade-of-membership analysis, was taken t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af031e0eeeef759c462fd5fef630bd8f
https://doi.org/10.3233/jad-2009-1055
https://doi.org/10.3233/jad-2009-1055
Autor:
Piotr Rieske, Barbara Krynska, Paul Brown, S. Ausim Azizi, Monika Witusik, Sylwia M. Gresner, Pawel P. Liberski, Krystyna Hulas-Bigoszewska
Publikováno v:
Brain Research. 1186:65-73
PrP(c) is a cellular isoform of the prion protein with an unknown normal function. One of the putative physiological roles of this protein is its involvement in cell differentiation. Recently, in vitro and in vivo studies showed that GFAP-positive ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53434578abbf4f7326e7a827de088416
https://doi.org/10.1016/j.brainres.2007.10.039
https://doi.org/10.1016/j.brainres.2007.10.039