Molecular characterization of the PhiKo endolysin from Thermus thermophilus HB27 bacteriophage phiKo and its cryptic lytic peptide RAP-29

Autor: Monika Szadkowska, Aleksandra Maria Kocot, Daria Sowik, Dariusz Wyrzykowski, Elzbieta Jankowska, Lukasz Pawel Kozlowski, Joanna Makowska, Magdalena Plotka

Publikováno v: Frontiers in Microbiology, Vol 14 (2024)

IntroductionIn the era of increasing bacterial resistance to antibiotics, new bactericidal substances are sought, and lysins derived from extremophilic organisms have the undoubted advantage of being stable under harsh environmental conditions. The P

Externí odkaz: https://doaj.org/article/e9fd1b722db4472a9a76c991b67d8b3d

Evaluation of GFP reporter utility for analysis of transcriptional slippage during gene expression

Autor: Ewa Wons, Dawid Koscielniak, Monika Szadkowska, Marian Sektas

Publikováno v: Microbial Cell Factories, Vol 17, Iss 1, Pp 1-10 (2018)

Abstract Background Epimutations arising from transcriptional slippage seem to have more important role in regulating gene expression than earlier though. Since the level and the fidelity of transcription primarily determine the overall efficiency of

Externí odkaz: https://doaj.org/article/326c0c2af53c40cbaf1aef3eb3a896a6

Molecular Characterization of a Novel Lytic Enzyme LysC from Clostridium intestinale URNW and Its Antibacterial Activity Mediated by Positively Charged N-Terminal Extension

Autor: Magdalena Plotka, Monika Szadkowska, Maria Håkansson, Rebeka Kovačič, Salam Al-Karadaghi, Björn Walse, Olesia Werbowy, Anna-Karina Kaczorowska, Tadeusz Kaczorowski

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 14, p 4894 (2020)

Peptidoglycan hydrolytic enzymes are considered to be a promising alternative to conventional antibiotics in combating bacterial infections. To identify novel hydrolytic enzymes, we performed a database search with the sequences of two thermostable e

Externí odkaz: https://doaj.org/article/fe357e4b7c3644e09650276ce66e2860

Going to extremes – a metagenomic journey into the dark matter of life

Autor: Alexandra Helleux, Håkon Dahle, Alexander Sczyrba, Karolina Kwiatkowska-Semrau, Anders Svensson, Ruoshi Zhang, Paul Terzian, Olesia Werbowy, Edda Olgudóttir, Gudmundur O. Hreggvidsson, Jonathan Vincent, Andrius Jasilionis, David Prangishvili, Thibaud Mas, Ehmke Pohl, Javier A. Linares-Pastén, Tobias Lutterman, Olafur H. Fridjonsson, Agata Jurczak-Kurek, Martin Steinegger, Arnthor Aevarsson, Justine Vanhalst, Mart Krupovic, Elisabet E. Gudmundsdottir, Sigurlaug Skirnisdottir, Milot Mirdita, Tadeusz Kaczorowski, Monika Szadkowska, Joanna Lange, Magdalena Plotka, Hildegard Watzlawick, François Enault, Magdalena Cichowicz-Cieślak, Sigmar K. Stefansson, Björn Walse, Jessica Louise Ray, Steffen A Lorentsen, Jörn Kalinowski, Slawomir Dabrowski, Josefin Ahlqvist, William Merre, Eric Olo Ndela, Lei Wang, Salam Al-Karadaghi, Sebastian Dorawa, Martin Welin, Francine Perler, Cathrine Pedersen, Tara Róbertsdóttir, Stefanie Freitag-Pohl, Anna-Karina Kaczorowska, Ruth-Anne Sandaa, Jérémy Courtin, Ilmur Jónsdóttir, Ewa Wons, Bjorn T. Adalsteinsson, Úlfur Áugúst Átlasson, Birkir Reynisson, Katrine Stange Overå, Christian Henke, Maria Håkansson, Julien Lebrat, Annika Jochheim, Mathilde Tourigny, Bas Vroling, Ying Liu, Eirin Glomsaker, Olav Lanes, Sigrídur Hjörleifdóttir, Sólveig K Pétursdóttir, Lukasz P. Kozlowski, Bernd Striberny, David Brandt, Agnieszka Morzywolek, Mickael Guérin, Julia Dusaucy, Ida Helene Steen, Clovis Galiez, Sigurd E Gundesø, J. Altenbuchner, Lilja Björk Jónsdóttir, Jørn Remi Henriksen, Katy A. S. Cornish, Tom van den Bergh, Eva Nordberg Karlsson, Johannes Söding, Hördur Gudmundsson, Hasan Arsin, Anita-Elin Fedøy, Emma J Tarrant, Samia Djeffane, Terese Solstad

Publikováno v: FEMS Microbiology Letters
FEMS Microbiology Letters, 2021, 368 (12), pp.fnab067. ⟨10.1093/femsle/fnab067⟩

The Virus-X-Viral Metagenomics for Innovation Value-project was a scientific expedition to explore and exploit uncharted territory of genetic diversity in extreme natural environments such as geothermal hot springs and deep-sea ocean ecosystems. Spec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ace0dc1df1a5c289378af4e9b0cf30
https://hal-pasteur.archives-ouvertes.fr/pasteur-03698255

Molecular characterization of the PhiKo endolysin from Thermus thermophilus HB27 bacteriophage phiKo and its cryptic lytic peptide RAP-29.

Autor: Szadkowska, Monika, Kocot, Aleksandra Maria, Sowik, Daria, Wyrzykowski, Dariusz, Jankowska, Elzbieta, Kozlowski, Lukasz Pawel, Makowska, Joanna, Plotka, Magdalena

Publikováno v: Frontiers in Microbiology; 2024, p1-16, 16p