Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Monika Swiontek"'
Autor:
Monika Swiontek, Joanna Wasko, Justyna Fraczyk, Krystian Galecki, Zbigniew J. Kaminski, Beata Kolesinska
Publikováno v:
Molecules, Vol 24, Iss 20, p 3706 (2019)
In this study, N-methylated analogs of hot-spots of insulin were designed and synthesized, in the expectation that they would inhibit the aggregation of both insulin hot-spots and the entire hormone. Synthesis of insulin “amyloidogenic” analogs c
Externí odkaz:
https://doaj.org/article/8dacb6da3fe94c2399ade77d78ea6467
Autor:
Monika Swiontek, Justyna Fraczyk, Joanna Wasko, Agata Chaberska, Lukasz Pietrzak, Zbigniew J. Kaminski, Lukasz Szymanski, Slawomir Wiak, Beata Kolesinska
Publikováno v:
Molecules, Vol 24, Iss 8, p 1600 (2019)
In this study, three independent methods were used to identify short fragment of both chains of human insulin which are prone for aggregation. In addition, circular dichroism (CD) research was conducted to understand the progress of aggregation over
Externí odkaz:
https://doaj.org/article/9ac252dcb72a455e8ccc4c970c2c8a74
Autor:
Beata Kolesinska, Justyna Fraczyk, Krystian Gałęcki, Joanna Wasko, Monika Swiontek, Zbigniew J. Kaminski
Publikováno v:
Molecules, Vol 24, Iss 20, p 3706 (2019)
Molecules
Volume 24
Issue 20
Molecules
Volume 24
Issue 20
In this study, N-methylated analogs of hot-spots of insulin were designed and synthesized, in the expectation that they would inhibit the aggregation of both insulin hot-spots and the entire hormone. Synthesis of insulin &ldquo
amyloidogenic&rdq
amyloidogenic&rdq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9184c99d3ab700a902d47e748caf6a
https://www.mdpi.com/1420-3049/24/20/3706
https://www.mdpi.com/1420-3049/24/20/3706
Autor:
Slawomir Wiak, Monika Swiontek, Joanna Wasko, Agata Chaberska, Lukasz Pietrzak, Zbigniew J. Kaminski, Beata Kolesinska, Justyna Fraczyk, Lukasz Szymanski
Publikováno v:
Molecules
Volume 24
Issue 8
Molecules, Vol 24, Iss 8, p 1600 (2019)
Volume 24
Issue 8
Molecules, Vol 24, Iss 8, p 1600 (2019)
In this study, three independent methods were used to identify short fragment of both chains of human insulin which are prone for aggregation. In addition, circular dichroism (CD) research was conducted to understand the progress of aggregation over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e560ff924ea8f418bf8a97fbffec16
Autor:
Monika Swiontek, Wojciech Lipinski, Zbigniew J. Kaminski, Danuta Drozdowska, Beata Kolesinska, Justyna Fraczyk
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 16:1435-1444
Dual action alkyl(aryl)amino-1,3,5-triazines functionalized with nitrogen mustards were obtained by treating 2-alkyl(aryl) amino-4-chloro-6-methoxy-1,3,5-triazines with amines or amino acid methyl esters, followed by reactions with 1,4-diazabicyclo[2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef3fe09d92391fcf7e78964cec187d7
https://doi.org/10.2174/1871520616666160204111430
https://doi.org/10.2174/1871520616666160204111430
Autor:
Zbigniew J. Kaminski, Justyna Fraczyk, Monika Swiontek, Kamil Rozniakowski, Wojciech Lipinski, Beata Kolesinska, Stanisław Wysocki, Krystian Gałęcki, Bertrand G. R. Dupont
Publikováno v:
Nanomedicine. 11:2083-2101
Aim: To identify the shortest components of A13-A19, B12-B17 fragments capable for fibrillation and to validate the dependability of aggregation on the presence of hydroxyl group engaged in the ‘tyrosine kissing’. Materials & methods: Fragments A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77e5ff4ae3f8757797bf4602bc7c1ec
https://doi.org/10.2217/nnm-2016-0100
https://doi.org/10.2217/nnm-2016-0100