Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Monika R. Leonard"'
Autor:
Malcolm A. Lyons, Henning Wittenburg, Renhua Li, Kenneth A. Walsh, Monika R. Leonard, Ron Korstanje, Gary A. Churchill, Martin C. Carey, Beverly Paigen
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 9, Pp 1763-1771 (2003)
A complex genetic basis determines the individual predisposition to develop cholesterol gallstones in response to environmental factors. We employed quantitative trait locus/loci (QTL) analyses of an intercross between inbred strains CAST/Ei (suscept
Externí odkaz:
https://doaj.org/article/9076136a911f4164a8e30e02f601a198
Autor:
Rebecca Wilcox, E. A. Zane, Gary M. Mawe, Mark T. Nelson, Monika R. Leonard, Brigitte Lavoie, Onesmo B. Balemba, Martin C. Carey, Aaron C. Bartoo, Bernhard Nausch
Publikováno v:
Neurogastroenterology & Motility. 24:e313-e324
BACKGROUND; Decreased gallbladder smooth muscle (GBSM) contractility is a hallmark of cholesterol gallstone disease, but the interrelationship between lithogenicity, biliary stasis, and inflammation are poorly understood. We studied a mouse model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::882703054bb92f7d9476bf9a7b740652
https://doi.org/10.1111/j.1365-2982.2012.01935.x
https://doi.org/10.1111/j.1365-2982.2012.01935.x
Autor:
Martin C. Carey, Henning Wittenburg, Kenneth Walsh, Renhua Li, Beverly Paigen, Gary A. Churchill, Malcolm A. Lyons, Monika R. Leonard, Ron Korstanje
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 9, Pp 1763-1771 (2003)
A complex genetic basis determines the individual predisposition to develop cholesterol gallstones in response to environmental factors. We employed quantitative trait locus/loci (QTL) analyses of an intercross between inbred strains CAST/Ei (suscept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5571c30c03d49d53a575f82f0ea70e
https://doi.org/10.1194/jlr.m300149-jlr200
https://doi.org/10.1194/jlr.m300149-jlr200
Autor:
Renhua Li, Henning Wittenburg, Kenneth Walsh, Malcolm A. Lyons, Monika R. Leonard, Martin C. Carey, Gary A. Churchill, Beverly Paigen
Publikováno v:
Physiological Genomics. 14:225-239
Cholesterol gallstone formation is a response to interactions between multiple genes and environmental stimuli. To determine the subset of cholesterol gallstone susceptibility ( Lith) genes possessed by strains CAST/Ei (susceptible) and 129S1/SvImJ (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a967a4a0bdc5abc26e0867eef0f428
https://doi.org/10.1152/physiolgenomics.00073.2003
https://doi.org/10.1152/physiolgenomics.00073.2003
Autor:
James G. Fox, Stephanie E. Woods, Kara R. Bernert, Elizabeth M. Nolan, Gary M. Mawe, Mark T. Whary, Joshua A. Hayden, Monika R. Leonard, Sureshkumar Muthupalani, Megan Brunjes Brophy, Martin C. Carey, Brigitte Lavoie
Publikováno v:
Prof. Nolan via Erja Kajosalo
“Black” pigment gallstones form in sterile gallbladder bile in the presence of excess bilirubin conjugates (“hyperbilirubinbilia”) from ineffective erythropoiesis, hemolysis, or induced enterohepatic cycling (EHC) of unconjugated bilirubin. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f65a62037b2a469208e87e7e76f7f4b
http://hdl.handle.net/1721.1/96251
http://hdl.handle.net/1721.1/96251
Autor:
David E. Cohen, Monika R. Leonard
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 10, Pp 2251-2260 (1996)
To predict bile salt-membrane interactions physiologically, we used an immobilized artificial membrane HPLC column that contains dimyristoyl-phosphatidylcholine molecules covalently linked to silica microspheres. Using a 90% aqueous (10% acetonitrile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44c6e883918ef2004fb12d89b734679
https://doi.org/10.1016/s0022-2275(20)39209-9
https://doi.org/10.1016/s0022-2275(20)39209-9
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 299(1)
Gallstones are frequent in patients with cystic fibrosis (CF). These stones are generally “black” pigment (i.e., Ca bilirubinate) with an appreciable cholesterol admixture. The pathophysiology and molecular mechanisms for this “mixed” gallsto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1f040ae715b3317a2c6cf9bd203343
https://pubmed.ncbi.nlm.nih.gov/20430874
https://pubmed.ncbi.nlm.nih.gov/20430874
Autor:
Bian B Yu, Folke Freudenberg, Jonathan N. Glickman, Martin C. Carey, Monika R. Leonard, Annemarie L Broderick
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 294(6)
The molecular pathogenesis of cystic fibrosis (CF) liver disease is unknown. This study investigates its earliest pathophysiological manifestations employing a mouse model carrying DeltaF508, the commonest human CF mutation. We hypothesized that, if
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7d7e2ff1ba0b6c2488011e0e6528b8
https://pubmed.ncbi.nlm.nih.gov/18436622
https://pubmed.ncbi.nlm.nih.gov/18436622
Autor:
Guylaine Bouchard, Arlin B. Rogers, Vivian Ng, Monika R. Leonard, Melanie Ihrig, James G. Fox, Martin C. Carey, Kirk J. Maurer
Publikováno v:
Gastroenterology. 128(4)
Background & Aims: Helicobacter spp are common inhabitants of the hepatobiliary and gastrointestinal tracts of humans and animals and cause a variety of well-described diseases. Recent epidemiologic results suggest a possible association between ente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08e1b2f582a963ee9bf2457f72915d7
https://pubmed.ncbi.nlm.nih.gov/15825095
https://pubmed.ncbi.nlm.nih.gov/15825095
Autor:
Malcolm A, Lyons, Henning, Wittenburg, Renhua, Li, Kenneth A, Walsh, Monika R, Leonard, Ron, Korstanje, Gary A, Churchill, Martin C, Carey, Beverly, Paigen
Publikováno v:
Journal of lipid research. 44(9)
A complex genetic basis determines the individual predisposition to develop cholesterol gallstones in response to environmental factors. We employed quantitative trait locus/loci (QTL) analyses of an intercross between inbred strains CAST/Ei (suscept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2df73a6f69ed4e4746c29e56328b0912
https://pubmed.ncbi.nlm.nih.gov/12810825
https://pubmed.ncbi.nlm.nih.gov/12810825