Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Monika Pękul"'
Autor:
Monika Pękul, Magdalena Szczepaniak, Paulina Kober, Natalia Rusetska, Beata J. Mossakowska, Szymon Baluszek, Artur Kowalik, Maria Maksymowicz, Grzegorz Zieliński, Jacek Kunicki, Przemysław Witek, Mateusz Bujko
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionCorticotroph pituitary neuroendocrine tumors (PitNETs) develop from ACTH-producing cells. They commonly cause Cushing’s disease (CD), however, some remain clinically silent. Recurrent USP8, USP48, BRAF and TP53 mutations occur in cortic
Externí odkaz:
https://doaj.org/article/3f226b8e125942638449b20825719fce
Autor:
Paulina Kober, Natalia Rusetska, Beata J. Mossakowska, Maria Maksymowicz, Monika Pękul, Grzegorz Zieliński, Andrzej Styk, Jacek Kunicki, Łukasz Działach, Przemysław Witek, Mateusz Bujko
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ObjectivePituitary neuroendocrine corticotroph tumors commonly cause Cushing’s disease (CD) that results from increased adrenocorticotropic hormone (ACTH) secretion by the pituitary tumor and consequent increase of cortisol levels in blood. However
Externí odkaz:
https://doaj.org/article/1a1d87f12f4d44ccbbb3de019e753037
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
PurposeCushing’s disease is the most common cause of endogenous hypercortisolemia due to a corticotroph pituitary tumor. Up-to-date there is no reliable biomarker of invasiveness among corticotroph tumors, while it is well established in the litera
Externí odkaz:
https://doaj.org/article/28cd82500a71426ca452e22a691bff9e
Autor:
Beata J. Mossakowska, Paulina Kober, Natalia Rusetska, Joanna Boresowicz, Maria Maksymowicz, Monika Pękul, Grzegorz Zieliński, Andrzej Styk, Jacek Kunicki, Tomasz Mandat, Mateusz Bujko
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2867
Corticotroph pituitary adenomas commonly cause Cushing’s disease (CD), but some of them are clinically silent. The reason why they do not cause endocrinological symptoms remains unclear. We used data from small RNA sequencing in adenomas causing CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e9d99eb0d4c87656c2992923ee14db
Publikováno v:
Pituitary
Purpose To explore the incidence of double pituitary adenomas in a tertiary center for pituitary surgery and asses their clinical, imaging and histopathological features. Methods The medical records of the patients operated on for pituitary tumors at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a619620789f649fe7729fe992f8c2f
http://europepmc.org/articles/PMC6842358
http://europepmc.org/articles/PMC6842358
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology
Frontiers in Endocrinology
PurposeCushing’s disease is the most common cause of endogenous hypercortisolemia due to a corticotroph pituitary tumor. Up-to-date there is no reliable biomarker of invasiveness among corticotroph tumors, while it is well established in the litera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9c12ceb2cea41ece206ba6c263c7a9
https://www.frontiersin.org/articles/10.3389/fendo.2021.672178/full
https://www.frontiersin.org/articles/10.3389/fendo.2021.672178/full
Autor:
Paulina Kober, Jerzy Ostrowski, Janusz A. Siedlecki, Maria Maksymowicz, Grzegorz Zieliński, Natalia Rusetska, Mateusz Bujko, Joanna Boresowicz, Monika Pękul, Agnieszka Paziewska, Natalia Zeber-Lubecka, Andrzej Styk, Jacek Kunicki
Publikováno v:
Journal of Clinical Medicine
Volume 10
Issue 3
Journal of Clinical Medicine, Vol 10, Iss 375, p 375 (2021)
Volume 10
Issue 3
Journal of Clinical Medicine, Vol 10, Iss 375, p 375 (2021)
Background: USP8 mutations are the most common driver changes in corticotroph pituitary tumors. They have direct effect on cells&rsquo
proteome through disturbance of ubiquitination process and also influence gene expression. The aim of this stu
proteome through disturbance of ubiquitination process and also influence gene expression. The aim of this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae39de91c87fcb4e125ddd49cdd903d
Autor:
Lukasz Kluczynski, Alicja Hubalewska-Dydejczyk, Maria Maksymowicz, Monika Pękul, Malgorzata Trofimiuk-Muldner, Bartosz Domagała, Grzegorz Sokolowski, Grzegorz Zieliński
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ffd802331d437b922b27a905fbfa9a1
https://doi.org/10.1530/endoabs.70.aep582
https://doi.org/10.1530/endoabs.70.aep582
Autor:
Kluczynski Lukasz, Malgorzata Trofimiuk-Muldner, Grzegorz Zieliński, Maria Maksymowicz, Alicja Hubalewska-Dydejczyk, Monika Pękul, Grzegorz Sokolowski
Publikováno v:
Journal of the Endocrine Society
Background. Double pituitary adenomas are a rare entity, which requires clinical attention and a careful follow-up. Case report. A 37-year-old man presented with left-sided painful gynecomastia. He denied typical symptoms of excessive growth hormone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82539f318be058cdda12eacbeb3815ce
http://europepmc.org/articles/PMC7207486
http://europepmc.org/articles/PMC7207486
Autor:
Grzegorz Zieliński, Paulina Kober, Mateusz Bujko, Jerzy Ostrowski, Janusz A. Siedlecki, Michalina Dąbrowska, Wiesław Bonicki, Jacek Kunicki, Agnieszka Paziewska, Agata Piaścik, Maria Maksymowicz, Natalia Rusetska, Joanna Boresowicz, Monika Pękul
Publikováno v:
European journal of endocrinology. 181(6)
Objective Pituitary corticotroph adenomas commonly cause Cushing’s disease (CD) but part of these tumours are hormonally inactive (silent corticotroph adenomas, SCA). USP8 mutations are well-known driver mutations in corticotrophinomas. Differences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1df153f08f260d3a2fbd6e63cd21e1
https://pubmed.ncbi.nlm.nih.gov/31581124
https://pubmed.ncbi.nlm.nih.gov/31581124