Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Monika Michaelis"'
Autor:
Monika Michaelis, Lorenzo Cupellini, Carl Mensch, Carole C. Perry, Massimo Delle Piane, Lucio Colombi Ciacchi
The most advanced structure prediction methods are powerless in exploring the conformational ensemble of disordered peptides and proteins and for this reason the "protein folding problem" remains unsolved. We present a novel methodology that enables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b0ff18ea42a1ba6d8fd0775229c1fb
https://doi.org/10.26434/chemrxiv-2022-6ccfd
https://doi.org/10.26434/chemrxiv-2022-6ccfd
Lessons from a Challenging System: Accurate Adsorption Free Energies at the Amino Acid/ZnO Interface
Autor:
Monika Michaelis, Carole C. Perry, Massimo Delle Piane, Dirk Rothenstein, Lucio Colombi Ciacchi
Publikováno v:
Journal of chemical theory and computation. 17(7)
We undertake steps to overcome four challenges that have hindered the understanding of ZnO/biomolecule interfaces at the atomic scale: parametrization of a classical force field, ZnO surface termination and amino acid protonation state in methanol, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd80c2f88d04ca5d3875c22f18ed21a
https://pubmed.ncbi.nlm.nih.gov/34191508
https://pubmed.ncbi.nlm.nih.gov/34191508
Autor:
Christian Debus, Lucio Colombi Ciacchi, Michael Maas, Monika Michaelis, Laura Treccani, Kurosch Rezwan, Steffen Lid, Daniel Carmona
Publikováno v:
Bioinspired, Biomimetic and Nanobiomaterials. 8:16-27
The iron storage protein ferritin is well known for its ability to mineralize iron oxides in its interior cavity. In this study, the authors investigated the mineralization behavior of H and L ferritin homopolymers assembled from individual subunits.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::228b6648b44f4848d889df4be81cf0e2
https://doi.org/10.1680/jbibn.18.00038
https://doi.org/10.1680/jbibn.18.00038
Publikováno v:
Physical Chemistry Chemical Physics. 21:4663-4672
Polypeptide based biosilica composites show promise as next generation multi-functional nano-platforms for diagnostics and bio-catalytic applications. Following the identification of a strong silica binder (LDHSLHS) by phage display, we conduct struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d970ff423cbd9a8b3b38d2f6588049e
https://doi.org/10.1039/c8cp07011c
https://doi.org/10.1039/c8cp07011c
Publikováno v:
Environmental Science & Technology. 51:4297-4305
Zinc oxide (ZnO) is of widespread use for numerous applications, including many in the cosmetic industry. Thus, ZnO particles are quite likely to enter the environment. ZnO may be harmful because of the release of cytotoxic Zn2+ ions during dissoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4a8ec96809bb562efb8c2e6baa56f2
https://doi.org/10.1021/acs.est.6b05732
https://doi.org/10.1021/acs.est.6b05732
Autor:
Susan Koeppen, Monika Michaelis, Lucio Colombi Ciacchi, Carole C. Perry, Mithun Parambath, Quentin S. Hanley, Aneeqa Fayyaz
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 35(44)
This paper describes novel adaptations of optically sectioned planar format assays to screen compounds for their affinities to materials surfaces. The novel platform, which we name optically sectioned indicator displacement assays (O-IDA), makes use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b771e69e3097cd8c53e068b7a9c9656
https://pubmed.ncbi.nlm.nih.gov/31609123
https://pubmed.ncbi.nlm.nih.gov/31609123
Autor:
Thomas Kowalik, Dorothea Brüggemann, Naiana Suter, Karsten Stapelfeldt, Monika Michaelis, Stephani Stamboroski, Irina Walter
Publikováno v:
Nano letters. 19(9)
As a key player in blood coagulation and tissue repair, fibrinogen has gained increasing attention to develop nanofibrous biomaterial scaffolds for wound healing. Current techniques to prepare protein nanofibers, like electrospinning or extrusion, ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86f8055156a2b1fe01aa65fa1d0b499
https://pubmed.ncbi.nlm.nih.gov/31418579
https://pubmed.ncbi.nlm.nih.gov/31418579
Autor:
Monika Michaelis, Lucio Colombi Ciacchi, M.J. Roe, Anna Sola-Rabada, Carole C. Perry, Hendrik Heinz, Daniel J. Oliver
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 34(28)
In this contribution, the effect of silica particle size (28 and 210 nm) and surface chemistry (i.e., hydroxyl, methyl, or amino groups) on peptide binding response is studied with a specific emphasis on the effect of the extent of functionalization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5482247acc170f69567af0293fa74ea9
https://pubmed.ncbi.nlm.nih.gov/29924624
https://pubmed.ncbi.nlm.nih.gov/29924624
Autor:
Nina Wurzler, Zhuo Li, Lucio Colombi Ciacchi, András Micsonai, Monika Michaelis, Alejandro Gil-Ley, Susan Köppen, Giovanni Bussi, Nils Hildebrand, Jonathan D. Hirst, Massimo Delle Piane, József Kardos
Adsorption of enzymes on solid surfaces may lead to conformational changes that reduce their catalytic conversion activity and are thus detrimental to the efficiency of biotechnology or biosensing applications. This work is a joint theoretical and ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5dea2b358e7084d3057c085058400f
https://hdl.handle.net/11583/2977637
https://hdl.handle.net/11583/2977637
Publikováno v:
The Analyst. 140(15)
We have developed a novel aptasensor based on single-molecule force spectroscopy (SMFS) capable of detecting mercury ions (Hg(2+)) with sub-nM sensitivity. The single-strand (ss) DNA aptamer used in this work is rich in thymine (T) and readily forms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259d6b698406f86001509743d142f75e
https://pubmed.ncbi.nlm.nih.gov/26075518
https://pubmed.ncbi.nlm.nih.gov/26075518