Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Monika McClellan"'
Autor:
Benny K, Abraham, Peter, Fritz, Monika, McClellan, Petra, Hauptvogel, Maria, Athelogou, Hiltrud, Brauch
Publikováno v:
Clinical Cancer Research. 11:1154-1159
Purpose: Breast cancer is composed of phenotypically diverse populations of cancer cells. The ability to form breast tumors has been shown by in vitro/in vivo studies to be restricted to epithelial tumor cells with CD44+/CD24−/low characteristics.
Autor:
Heikki Toomes, Heyo K. Kroemer, Monika McClellan, Klaus Bosslet, Bernhard Sperker, Manfred Gerken, Godehard Friedel, Janne T. Backman, Thomas E. Mürdter, Peter Fritz, Monika Schick
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 301:223-228
HMR 1826 (N-[4-beta-Glucuronyl-3-nitrobenzyl-oxycarbonyl]doxorubicin) is a nontoxic glucuronide prodrug from which active doxorubicin is released by beta-glucuronidase. Preclinical studies aimed at dose optimization of HMR 1826, based on intratumoral
Autor:
Rainer Dierkesmann, Monika McClellan, Godehard Friedel, Christoph A. Ritter, Frank Bohnenstengel, Heyo K. Kroemer, Peter Fritz, Michel Eichelbaum, Heikki Toomes, Albert Linder
Publikováno v:
Cancer chemotherapy and pharmacology. 45(1)
Purpose: The alkylating cytostatic prodrug cyclophosphamide is bioactivated by the human cytochrome P450 enzyme system. Since these enzymes are not only expressed in human liver, but also in extrahepatic tissue, local bioactivation of this drug may p
Autor:
E, Mrdter Thomas, Godehard, Friedel, T, Backman Janne, Monika, McClellan, Monika, Schick, Manfred, Gerken, Klaus, Bosslet, Peter, Fritz, Heikki, Toomes, K, Kroemer Heyo, Bernhard, Sperker
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; April 2002, Vol. 301 Issue: 1 p223-8, 6p
Autor:
Peter Fritz, Thomas E. Mürdter, Monika McClellan, Andreas Gerteis, W. Simon, Maike Sonnenberg, Susanne Gutzeit, Heiko van der Kuip, Walter E. Aulitzky
Publikováno v:
BMC Cancer
BMC Cancer, Vol 6, Iss 1, p 86 (2006)
BMC Cancer, Vol 6, Iss 1, p 86 (2006)
Background Sensitivity of breast tumors to anticancer drugs depends upon dynamic interactions between epithelial tumor cells and their microenvironment including stromal cells and extracellular matrix. To study drug-sensitivity within different compa
Autor:
Matthias Freiwald, Peter Fritz, Andreas Kirschbaum, Anagnostis Valotis, Monika McClellan, Godehard Friedel, Petra Högger, Thomas E. Mürdter, Michael Thomas
Publikováno v:
Respiratory Research
Respiratory Research, Vol 6, Iss 1, p 21 (2005)
Respiratory Research, Vol 6, Iss 1, p 21 (2005)
Background The pulmonary residence time of inhaled glucocorticoids as well as their rate and extend of absorption into systemic circulation are important facets of their efficacy-safety profile. We evaluated a novel approach to elucidate the pulmonar
Autor:
van der Kuip, Heiko1 heiko.van-der-kuip@ikp-stuttgart.de, Mürdter, Thomas E1 thomas.muerdter@ikp-stuttgart.de, Sonnenberg, Maike1 maike.sonnenberg@ikp-stuttgart.de, McClellan, Monika1 monika.mcclellan@ikp-stuttgart.de, Gutzeit, Susanne1 susanne.gutzeit@ikp-stuttgart.de, Gerteis, Andreas2 andreas.gerteis@rbk.de, Simon, Wolfgang2 wolfgang.simon@rbk.de, Fritz, Peter3 peter.fritz@rbk.de, Aulitzky, Walter E4 walter.aulitzky@rbk.de
Publikováno v:
BMC Cancer. 2006, Vol. 6, p86-11. 11p. 11 Color Photographs, 1 Diagram, 11 Graphs.
Autor:
Stuelten, Christina H.1,2,3 chrisstu@mail.nih.gov, Miriam B. Buck2 miriam.buck@ikp-stuttgart.de, Dippon, Juergen4 dippon@mathematik.uni-stuttgart.de, Roberts, Anita B.3 Robertsa@mail.nih.gov, Fritz, Peter1 peter.fritz@rbk.de, Knabbe, Cornelius1 cornelius.knabbe@rbk.de
Publikováno v:
BMC Cancer. 2006, Vol. 6, p25-10. 10p. 11 Diagrams, 2 Charts, 3 Graphs.
Autor:
Freiwald, Matthias1 freiwald@pzlc.uni-wuerzburg.de, Valotis, Anagnostis1 valotis@pzlc.uni-wuerzburg.de, Kirschbaum, Andreas2, McClellan, Monika3, Mürdter, Thomas3, Fritz, Peter4, Friedel, Godehard2, Thomas, Michael5, Högger, Petra1 hogger@pzlc.uni-wuerzburg.de
Publikováno v:
Respiratory Research. 2005, Vol. 6, p21-13. 13p.
Autor:
Bohnenstengel, Frank, Friedel, Godehard, Ritter, Christoph A., McClellan, Monika, Fritz, Peter, Eichelbaum, Michel, Linder, Albert, Toomes, Heikki, Dierkesmann, Rainer, Kroemer, Heyo K.
Publikováno v:
Cancer Chemotherapy & Pharmacology; Jan2000, Vol. 45 Issue 1, p63-68, 6p