Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Monika Manne"'
Autor:
Dean Lee, Monika Manne, Roshan Kumar, Rebecca Silver, Alexandra Staskus, Julianna Crivello, Zhiyuan Wang, Dohyun Lee, Ross Fulton, Zhizhan Gu, Christos Hatzis, Francisco Adrian, Andreas Raue, Liang Schweizer
Publikováno v:
Cancer Research. 82:618-618
The discovery of predictive biomarkers of response is critical for forecasting patient benefit from novel immune-modulatory therapeutics. However, their discovery is hindered by the complexity of the drug modes of action and the lack of adequate biol
Autor:
Sami Ellouze, Charina Ortega, Wenhua Xu, Xing Cai, Alexandra Staskus, Zhiyuan Wang, Jinping Gan, Liang Schweizer, Zachary Duda, Carine George, Sophie Foulon, Rebecca Silver, Juliana Crivello, Nicola Beltraminelli, Francisco Adrian, Shuo Wei, Jennifer Watkins-Yoon, Andreas Raue, Qian Zhang, Yun-Yueh Lu, Dean Lee, Mingjie Chen, Monika Manne, Ross B. Fulton, He Zhou
Publikováno v:
Cancer Research. 81:1883-1883
Despite the success of immune check point inhibition, identification of other pathways capable of modulating the immune response against the tumor remains challenging. T-cell co-stimulation has been investigated with limited clinical success so far d
Autor:
Ross B. Fulton, Zhiyuan Wang, Rebecca Silver, Ruina Jin, Joyce Pi, Jinping Gan, Zachery Duda, Andreas Raue, Monika Manne, Yuan Wang, Hongkai Zhang, Wenhua Xu, Xing Cai, Francisco Adrian, Carine George, Yun-Yueh Lu, Sophie Foulon, Sami Ellouze, Dean Lee, Charina Ortega, Robert Petit, Liang Schweizer, Julianna Crivello, Alexandra Staskus, Nicola Beltraminelli
Publikováno v:
Cancer Research. 81:1882-1882
Agonist OX40 antibodies have shown promising pre-clinical activities, but their clinical activities have been limited thus far. Several reasons may account for this limited clinical activity, including sub-optimal antibody design, dose selection, and
Autor:
Ross B. Fulton, Julianna Crivello, Francisco Adrian, Zachary Duda, Dean Lee, Charina Ortega, Roshan Kumar, Liang Schweizer, Matt Delince, Monika Manne, Andreas Raue, Alexandra Staskus
Publikováno v:
Cancer Research. 80:PO-048
Immunomodulatory antibodies such as checkpoint inhibitors are showing very promising results in the clinic, but only a minority of patients respond to treatment and it is still challenging to identify these subpopulations. Prospective identification