The Absence of (p)ppGpp Renders Initiation of Escherichia coli Chromosomal DNA Synthesis Independent of Growth Rates

Autor: Llorenç Fernández-Coll, Monika Maciag-Dorszynska, Krishma Tailor, Stephen Vadia, Petra Anne Levin, Agnieszka Szalewska-Palasz, Michael Cashel

Publikováno v: mBio, Vol 11, Iss 2 (2020)

ABSTRACT The initiation of Escherichia coli chromosomal DNA replication starts with the oligomerization of the DnaA protein at repeat sequences within the origin (ori) region. The amount of ori DNA per cell directly correlates with the growth rate. D

Externí odkaz: https://doaj.org/article/c70362e54d2e42d18cd060baed7d9443

A comprehensive pharmacological analysis of fenoterol and its derivatives to unravel the role of β2-adrenergic receptor in zebrafish

Autor: Monika Maciag, Wojciech Plazinski, Wojciech Pulawski, Michal Kolinski, Krzysztof Jozwiak, Anita Plazinska

Publikováno v: Biomedicine & Pharmacotherapy. 160:114355

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c615a86ee1cf70918fbe0ebacee970e6
https://doi.org/10.1016/j.biopha.2023.114355

Pharmacological assessment of zebrafish-based cardiotoxicity models

Autor: Monika Maciag, Artur Wnorowski, Malgorzata Mierzejewska, Anita Plazinska

Publikováno v: Biomedicine & Pharmacotherapy, Vol 148, Iss, Pp 112695-(2022)

Cardiotoxicity remains the most common reason for failure during drug development. Recently, the zebrafish (Danio rerio) model has emerged for the evaluation of drug-dependent cardiotoxicity and for the identification of cardioprotective molecules. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c6e2ad91cffcc2403b42a5382102a7
https://doi.org/10.1016/j.biopha.2022.112695

Multiple links connect central carbon metabolism to DNA replication initiation and elongation in Bacillus subtilis

Autor: Hamid, Nouri, Anne-Françoise, Monnier, Solveig, Fossum-Raunehaug, Monika, Maciag-Dorszynska, Armelle, Cabin-Flaman, François, Képès, Grzegorz, Wegrzyn, Agnieszka, Szalewska-Palasz, Vic, Norris, Kirsten, Skarstad, Laurent, Janniere

Publikováno v: DNA Research
DNA Research, Oxford University Press (OUP), 2018, 25 (6), pp.641-653. ⟨10.1093/dnares/dsy031⟩
DNA Research, 2018, 25 (6), pp.641-653. ⟨10.1093/dnares/dsy031⟩
DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes

International audience; DNA replication is coupled to growth by an unknown mechanism. Here, we investigated this coupling by analyzing growth and replication in 15 mutants of central carbon metabolism (CCM) cultivated in three rich media. In about on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dd2ef98edb9f24d86412e74b35f9e8f2
https://hal.archives-ouvertes.fr/hal-02180951

The use of real-time PCR technique in the detection of novel protein 4.2 gene mutations that coexist with thalassaemia alpha in a single patient

Autor: Anna Adamowicz-Salach, Alicja Siwicka, Monika Maciag, Beata Burzynska, Justyna Spychalska

Publikováno v: European Journal of Haematology

Alpha-thalassaemia is a very rare disease in Northern Europe in contrast to hereditary spherocytosis that is associated with red blood cell membrane defects. We report here alpha-thalassaemia case who was also found to bear the erythrocyte membrane p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ac9bf3aa639b9fa3a3e78dd02052f1
https://doi.org/10.1111/j.1600-0609.2009.01289.x