Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Monika Liguz-Lecznar"'
Autor:
Aleksandra Gawryluk, Anita Cybulska-Klosowicz, Agata Charzynska, Renata Zakrzewska, Alicja Sobolewska, Malgorzata Kossut, Monika Liguz-Lecznar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Aging-related biochemical changes in nerve cells lead to dysfunctional synapses and disrupted neuronal circuits, ultimately affecting vital processes such as brain plasticity, learning, and memory. The imbalance between excitation and inhibi
Externí odkaz:
https://doaj.org/article/7b8334e2e3094540ae43bd097a139f26
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 312 (2022)
Despite the obvious differences in the pathophysiology of distinct neuropsychiatric diseases or neurodegenerative disorders, some of them share some general but pivotal mechanisms, one of which is the disruption of excitation/inhibition balance. Such
Externí odkaz:
https://doaj.org/article/bf5e3700527d4e229d5fd0ef542eebaf
Autor:
Anna Posluszny, Monika Liguz-Lecznar, Danuta Turzynska, Renata Zakrzewska, Maksymilian Bielecki, Malgorzata Kossut
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144415 (2015)
Experience-induced plastic changes in the cerebral cortex are accompanied by alterations in excitatory and inhibitory transmission. Increased excitatory drive, necessary for plasticity, precedes the occurrence of plastic change, while decreased inhib
Externí odkaz:
https://doaj.org/article/c3aa65437b544090b5575fa8ccbc5305
Publikováno v:
Neural Plasticity, Vol 2013 (2013)
Age-related brain injuries including stroke are a leading cause of morbidity and mental disability worldwide. Most patients who survive stroke experience some degree of recovery. The restoration of lost functions can be explained by neuronal plastici
Externí odkaz:
https://doaj.org/article/4c7f46defebf4de687884d21cca659b1
Publikováno v:
Brain Structure & Function
Inhibitory interneurons in the cerebral cortex contain specific proteins or peptides characteristic for a certain interneuron subtype. In mice, three biochemical markers constitute non-overlapping interneuron populations, which account for 80–90% o
Autor:
Dominik Kanigowski, Malgorzata Kossut, R. Zakrzewska, Monika Liguz-Lecznar, A. Posluszny, G. Dobrzanski, A. Lukomska, Joanna Urban-Ciecko
Gaba-ergic neurons are a diverse cell class with extensive influence over cortical processing, but their role in experience-dependent plasticity is not completely understood. Here we addressed the role of cortical somatostatin- (SOM-INs) and vasoacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1869ca069c4ad04f698aee8dabe65275
Publikováno v:
Postępy Biochemii. 64:213-221
Somatostatyna jest peptydem uczestniczącym w wielu szlakach biochemicznych i sygnałowych. Działa ona za pośrednictwem pięciu receptorów (SSTR 1-5) należących do rodziny receptorów sprzężonych z białkiem G. Wszystkie receptory somatostatyn
Autor:
Monika Liguz-Lecznar, Aleksandra Rozycka, Alicja Sobolewska, Zuzanna Misiewicz, Tomasz Maciej Stepniewski, Agata Charzynska, Malgorzata Kossut
Publikováno v:
ACS chemical neuroscience. 10(11)
Molecular synaptic aging perturbs neurotransmission and decreases the potential for neuroplasticity. The direction and degree of changes observed in aging are often region or cell specific, hampering the generalization of age-related effects. Using r
Autor:
Aleksandra Gawryluk, Katarzyna Hetmańczyk, Karolina Kołosowska, Marek Gryz, Anna Skórzewska, Aleksandra Wisłowska-Stanek, Agnieszka Ługowska, Małgorzata Lehner, Monika Liguz-Lecznar, Alicja Sobolewska
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 93
The aim of this study was to assess the influence of chronic restraint stress on amphetamine (AMPH)-related appetitive 50-kHz ultrasonic vocalisations (USVs) in rats differing in freezing duration in a contextual fear test (CFT), i.e. HR (high-anxiet
Autor:
Paweł Krząścik, Janusz Szyndler, Monika Liguz-Lecznar, Alicja Sobolewska, Aleksandra Wisłowska-Stanek, Marek Gryz, Anna Skórzewska, Karolina Kołosowska, Adam Płaźnik, Danuta Turzyńska, Małgorzata Lehner
Publikováno v:
Behavioural brain research. 359
The aim of the study was to assess appetitive responses and central dopaminergic neurotransmission in passive and active rats divided according to their immobility time in the Porsolt swim test and exposed to restraint stress. Passive rats had more e