Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Monika Kubacka"'
Autor:
Magdalena Kotańska, Monika Zadrożna, Monika Kubacka, Kamil Mika, Katarzyna Szczepańska, Barbara Nowak, Alessio Alesci, Anthea Miller, Eugenia Rita Lauriano, Katarzyna Kieć-Kononowicz
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 858 (2024)
Background: Numerous studies highlight the critical role that neural histamine plays in feeding behavior, which is controlled by central histamine H3 and H1 receptors. This is the fundamental motivation for the increased interest in creating histamin
Externí odkaz:
https://doaj.org/article/a89f1fff18ba46f69f8f2291d9821f40
Autor:
Grzegorz Kazek, Monika Głuch-Lutwin, Barbara Mordyl, Elżbieta Menaszek, Monika Kubacka, Anna Jurowska, Dariusz Cież, Bartosz Trzewik, Janusz Szklarzewicz, Monika A. Papież
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 229 (2024)
In the text, the synthesis and characteristics of the novel ONS-type vanadium (V) complexes with thioanilide derivatives of amino acids are described. They showed the inhibition of human protein tyrosine phosphatases (PTP1B, LAR, SHP1, and SHP2) in t
Externí odkaz:
https://doaj.org/article/12c73147d33048dbb272b70c13fc6acf
Autor:
Magdalena Kotańska, Konrad Wojtaszek, Monika Kubacka, Marek Bednarski, Noemi Nicosia, Marek Wojnicki
Publikováno v:
Antioxidants, Vol 13, Iss 1, p 13 (2023)
Caramel, defined as a coloring agent and as an antioxidant, is used in several kinds of food products and is consumed by many people in different amounts. In our research we showed that the caramelization of sucrose under special conditions leads to
Externí odkaz:
https://doaj.org/article/073db439cb5e4e44a56f18160cd91188
Autor:
Monika Kubacka, Barbara Nowak, Monika Zadrożna, Małgorzata Szafarz, Gniewomir Latacz, Henryk Marona, Jacek Sapa, Szczepan Mogilski, Marek Bednarski, Magdalena Kotańska
Publikováno v:
Metabolites, Vol 13, Iss 11, p 1130 (2023)
Excessive fructose consumption may lead to metabolic syndrome, metabolic dysfunction-associated fatty liver disease (MAFLD) and hypertension. α1-adrenoceptors antagonists are antihypertensive agents that exert mild beneficial effects on the metaboli
Externí odkaz:
https://doaj.org/article/d003b1d9fb2148d98d4eab2769f57ff8
Autor:
Szczepan Mogilski, Monika Kubacka, Artur Świerczek, Elżbieta Wyska, Katarzyna Szczepańska, Jacek Sapa, Katarzyna Kieć-Kononowicz, Dorota Łażewska
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1481 (2023)
Itch and pain are closely related but distinct sensations that share largely overlapping mediators and receptors. We hypothesized that the novel, multi-target compound E153 has the potential to attenuate pain and pruritus of different origins. After
Externí odkaz:
https://doaj.org/article/6cd04dd7b53146d69e2538b00099cbd6
Autor:
Monika Marcinkowska, Monika Kubacka, Agnieszka Zagorska, Anna Jaromin, Nikola Fajkis-Zajaczkowska, Marcin Kolaczkowski
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 145, Iss , Pp 112424- (2022)
Small drug-like molecules that can block the function of serotonin 5-HT2A receptors have garnered considerable attention due to their ability to inhibit platelet aggregation and the possible prevention of atherosclerotic lesions. Although clinical da
Externí odkaz:
https://doaj.org/article/0bb8cee8aad04c15b6bfe085a004d6ad
Autor:
Monika Marcinkowska, Magdalena Kotańska, Agnieszka Zagórska, Joanna Śniecikowska, Monika Kubacka, Agata Siwek, Adam Bucki, Maciej Pawłowski, Marek Bednarski, Jacek Sapa, Małgorzata Starek, Monika Dąbrowska, Marcin Kołaczkowski
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 536-545 (2018)
Despite the substantial clinical success of aspirin and clopidogrel in secondary prevention of ischemic stroke, up to 40% of patients remain resistant to the available antiplatelet treatment. Therefore, there is an urgent clinical need to develop nov
Externí odkaz:
https://doaj.org/article/ca47822105e94d8aa84ccd74b1b779d4
Autor:
Magdalena Kotańska, Monika Kubacka, Marek Bednarski, Noemi Nicosia, Małgorzata Szafarz, Wojciech Jawień, Christa E. Müller, Katarzyna Kieć-Kononowicz
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 799 (2021)
GPR18 is an orphan GPCR that is activated by the cannabinoid tetrahydrocannabinol (THC). Emerging evidence indicates its involvement in the control of cardiovascular functions, including heart rate, contractility, vascular tone, as well as blood pres
Externí odkaz:
https://doaj.org/article/90df7f750537417e973b05928031cf16
Autor:
Magdalena Kowalska, Łukasz Fijałkowski, Monika Kubacka, Kinga Sałat, Grzegorz Grześk, Jacek Nowaczyk, Alicja Nowaczyk
Publikováno v:
Molecules, Vol 26, Iss 12, p 3522 (2021)
Tiagabine is an antiepileptic drug used for the treatment of partial seizures in humans. Recently, this drug has been found useful in several non-epileptic conditions, including anxiety, chronic pain and sleep disorders. Since tachycardia—an impair
Externí odkaz:
https://doaj.org/article/fb506d4cf75f435fb676ac94ae02bc74
Autor:
Monika Kubacka, Szczepan Mogilski, Monika Zadrożna, Barbara Nowak, Małgorzata Szafarz, Bartosz Pomierny, Henryk Marona, Anna Waszkielewicz, Wojciech Jawień, Jacek Sapa, Marek Bednarski, Joanna Knutelska, Magdalena Kotańska
Publikováno v:
Pharmaceuticals, Vol 14, Iss 5, p 477 (2021)
Background: Quinazoline α1-adrenoceptors antagonists have been shown to exert moderately favorable effects on the metabolic profile in hypertensive patients. However, based on AntiHypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Tri
Externí odkaz:
https://doaj.org/article/73a418c7d14044c1b2b8d64d6f89d199