Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Monika Krampert"'
Autor:
Patricia Recio‐López, Ismael Valladolid‐Acebes, Philipp Hadwiger, Markus Hossbach, Monika Krampert, Carla Prata, Per‐Olof Berggren, Lisa Juntti‐Berggren
Publikováno v:
BioFactors. 49:153-172
Apolipoprotein CIII (apoCIII) is increased in obesity-induced insulin resistance and type-2 diabetes. Emerging evidences support the advantages of small interfering RNAs (siRNAs) to target disease-causing genes. The aim of this study was to develop s
Autor:
Hans-Peter Vornlocher, Brown Jonathan Miles, Monika Krampert, James E. Dahlman, Kristin K.H. Neuman, Carla Alexandra Hernandez Prata, Philipp Hadwiger
Publikováno v:
Nucleic Acid Therapeutics
Small interfering RNAs (siRNAs) conjugated to N-acetylgalactosamine (GalNAc) ligands have been used to treat disease in patients. However, conjugates with other ligands deliver siRNA less efficiently, limiting the development of new targeted therapie
Autor:
Shelley N.-M. Thai, Sabine Werner, Monika Krampert, M. Luisa Iruela-Arispe, Nathan V. Lee, Sandra Kuenzle
Publikováno v:
Journal of Biological Chemistry. 280:23844-23852
The metalloproteinase ADAMTS1 (a disintegrin and metalloproteinase with thrombospondin motifs) is induced under inflammatory conditions, and it is also a potent inhibitor of angiogenesis. Due to these properties, we speculated about the role of ADAMT
Autor:
William C. Parks, Eckhard Wolf, Philippe Bugnon, Sabine Werner, Monika Krampert, Wilhelm Bloch, Thomas Rülicke, Monique Aumailley, Takako Sasaki
Publikováno v:
Molecular Biology of the Cell. 15:5242-5254
The matrix metalloproteinase stromelysin-2 is expressed in keratinocytes of the epithelial tongue of skin wounds, suggesting a role in keratinocyte migration. Here, we show that stromelysin-2 enhances migration of cultured keratinocytes. To gain insi
Autor:
Hongbing Zhang, Lewis T. Williams, Richard Grose, Sabine Werner, Monika Krampert, Jessica Dessimoz, Tobias A. Beyer
Publikováno v:
European Journal of Cell Biology. 83:3-11
Summary Alternative splicing in the extracellular domain is a characteristic feature of members of the fibroblast growth factor receptor (FGFR) family. This splicing event generates receptor variants, which differ in their ligand binding specificitie
Autor:
Silke Werner, Monika Krampert, Hans-Dietmar Beer, Ulrich auf dem Keller, Susanne Braun, Sabine Werner, Clive Dickson, Mischa Müller
Publikováno v:
European Journal of Cell Biology. 81:375-382
Autor:
Alain Israël, Arianna Nenci, Atiye Toksoy, Gilles Courtois, Thomas Krieg, Martin Hafner, Reinhard Gillitzer, Ingo Haase, Matthias Goebeler, Klaus Rajewsky, Manolis Pasparakis, Marc Schmidt-Supprian, Monika Krampert
Publikováno v:
Nature. 417:861-866
The I kappa B kinase (IKK), consisting of the IKK1 and IKK2 catalytic subunits and the NEMO (also known as IKK gamma) regulatory subunit, phosphorylates I kappa B proteins, targeting them for degradation and thus inducing activation of NF-kappa B (re
Autor:
Anke Geick, Kerstin Jahn-Hofmann, Monika Krampert, Jennifer Rice, Andrea Schuster, Khursheed Anwer, Richard Congo, Hans-Peter Vornlocher, Gregory Slobodkin, Jason G. Fewell, Diane McClure, Matthias John, Jeff Sparks, Angela Rea-Ramsey, Kevin Polach, Majed Matar, Elaine Brunhoeber
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 20(1)
We have designed a series of versatile lipopolyamines which are amenable to chemical modification for in vivo delivery of small interfering RNA (siRNA). This report focuses on one such lipopolyamine (Staramine), its functionalized derivatives and the
Autor:
Ulrich Bogdahn, Frank-Peter Wachs, Jonathan M. Yingling, Robert Aigner, Sridhar Reddy Chirasani, Ludwig Aigner, Rainer Heuchel, Monika Krampert, Carl-Henrik Heldin
Publikováno v:
Molecular and cellular biology. 30(14)
Members of the transforming growth factor beta (TGF-beta) family of proteins modulate the proliferation, differentiation, and survival of many different cell types. Neural stem and progenitor cells (NPCs) in the adult brain are inhibited in their pro
Autor:
Hans Robert Kalbitzer, Bernadette Lehner, Sonja Plötz, Francisco J. Rivera, Werner Kremer, Paul Ramm, Ulrich Bogdahn, Sebastien Couillard-Despres, Ludwig Aigner, Monika Krampert
Publikováno v:
Stem cells (Dayton, Ohio). 27(2)
In vivo visualization of endogenous neural progenitor cells (NPCs) is crucial to advance stem cell research and will be essential to ensure the safety and efficacy of neurogenesis-based therapies. Magnetic resonance spectroscopic imaging (i.e., spati