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pro vyhledávání: '"Monika Kohnke"'
Correction: AAV-Mediated Gene Therapy for Choroideremia: Preclinical Studies in Personalized Models.
Autor:
Vidyullatha Vasireddy, Jason A Mills, Rajashekhar Gaddameedi, Etiena Basner-Tschakarjan, Monika Kohnke, Aaron D Black, Krill Alexandrov, Shangzhen Zhou, Albert M Maguire, Daniel C Chung, Helen Mac, Lisa Sullivan, Paul Gadue, Jeannette L Bennicelli, Deborah L French, Jean Bennett
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129982 (2015)
Externí odkaz:
https://doaj.org/article/3ff5786d3a4b4f30b1fbda3b6a3357c4
Autor:
Vidyullatha Vasireddy, Jason A Mills, Rajashekhar Gaddameedi, Etiena Basner-Tschakarjan, Monika Kohnke, Aaron D Black, Krill Alexandrov, Shangzhen Zhou, Albert M Maguire, Daniel C Chung, Helen Mac, Lisa Sullivan, Paul Gadue, Jeannette L Bennicelli, Deborah L French, Jean Bennett
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e61396 (2013)
Choroideremia (CHM) is an X- linked retinal degeneration that is symptomatic in the 1(st) or 2(nd) decade of life causing nyctalopia and loss of peripheral vision. The disease progresses through mid-life, when most patients become blind. CHM is a fav
Externí odkaz:
https://doaj.org/article/5013639fa82b45b9b6483d086bbfb112
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/f9764661da97459abe091a943bdaea06
Autor:
Monika Köhnke, Christine Delon, Marcus L Hastie, Uyen T T Nguyen, Yao-Wen Wu, Herbert Waldmann, Roger S Goody, Jeffrey J Gorman, Kirill Alexandrov
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81758 (2013)
Protein prenylation is a widespread post-translational modification in eukaryotes that plays a crucial role in membrane targeting and signal transduction. RabGTPases is the largest group of post-translationally C-terminally geranylgeranylated. All Ra
Externí odkaz:
https://doaj.org/article/dc24756c647a4436b65d4a1980908b6b
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66425 (2013)
Hundreds of eukaryotic signaling proteins require myristoylation to functionally associate with intracellular membranes. N-myristoyl transferases (NMT) responsible for this modification are established drug targets in cancer and infectious diseases.
Externí odkaz:
https://doaj.org/article/85cd1ded5fa44cfeadbc2fb9b2a0096a