Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Monika Kadela-Tomanek"'
Autor:
Klaudia Stocerz, Arkadiusz Sokal, Mariusz Kuczera, Monika Kadela-Tomanek, Kinga Orlińska, Paweł Olczyk
Publikováno v:
Annales Academiae Medicae Silesiensis, Vol 78, Pp 138-145 (2024)
Obesity is a chronic disease that constitutes a global problem and a serious challenge to public health. In the course of this disease, excessive accumulation of fat tissue occurs in the body, which not only leads to an increased risk of health compl
Externí odkaz:
https://doaj.org/article/688569dc111446af91f7e25129fb3770
Publikováno v:
Annales Academiae Medicae Silesiensis, Vol 78, Pp 49-60 (2024)
One of the branches of traditional Chinese medicine (TCM) is herbal medicine. In this paper, we focus on the biological activity of substances belonging to flavonoids and specific examples of their impact on various body systems. Flavonoids are a gro
Externí odkaz:
https://doaj.org/article/1366ca8008bc49c9a2d58c8df11d851f
Autor:
Arkadiusz Sokal, Roman Wrzalik, Joanna Klimontko, Elwira Chrobak, Ewa Bębenek, Monika Kadela-Tomanek
Publikováno v:
Molbank, Vol 2023, Iss 4, p M1747 (2023)
Quinoline and isoquinoline moieties occur in many natural and synthetic compounds exhibiting high biological activity. The purpose of this study was to analyze the chemical structures of 5,8-quinolinedione and 5,8-isoquinoline derivatives using FT-IR
Externí odkaz:
https://doaj.org/article/0f19920eee884ebe95fcc8a5570a2913
Publikováno v:
Molbank, Vol 2023, Iss 4, p M1741 (2023)
New derivative of 28-acetylbetulin containing a phenylpropynoyl moiety at the C-3 position was obtained by Steglich method. The chemical structure of this compound has been determined through 1H NMR, 13C NMR, IR, EI MS and HRMS. The antiproliferative
Externí odkaz:
https://doaj.org/article/fa105f60944a421e92050d528ff4cd55
Publikováno v:
Molbank, Vol 2023, Iss 3, p M1686 (2023)
The aim of the work was the synthesis of a new 28-acetylbetulin derivative containing an ester group with a carbon–carbon triple bond in the C3 position. To obtain the title compound, a reaction of 28-acetylbetulin with but-2-ynoic acid was carried
Externí odkaz:
https://doaj.org/article/5535be99c39f4085be5393fab158e547
Autor:
Monika Kadela-Tomanek, Arkadiusz Sokal, Klaudia Stocerz, Ewa Bębenek, Elwira Chrobak, Paweł Olczyk
Publikováno v:
Applied Sciences, Vol 14, Iss 5, p 1695 (2024)
Bioavailability describes the properties that determine the passage of a compound through biological barriers. In many cases, bioavailability depends on the lipophilicity of the compound. In this study, the lipophilicity as well as other bioavailabil
Externí odkaz:
https://doaj.org/article/068a7ad564e04a23bbf19467b9dcffdb
Publikováno v:
Applied Sciences, Vol 14, Iss 4, p 1452 (2024)
Viral diseases affecting both humans and animals are a serious public problem. Chemical modifications of the structure of compounds of natural origin, e.g., betulin, seem to be a promising model in the search for new antiviral agents. The subject of
Externí odkaz:
https://doaj.org/article/c375b6dc93224e4cbbfcffaab096d4c6
Publikováno v:
Crystals, Vol 13, Iss 10, p 1488 (2023)
The molecular structure of 3-diethoxyphosphoryl-28-[1-(1-deoxy-β-D-glucopyranosyl)-1H-1,2,3-triazol-4-yl]carbonylbetulin was investigated through various experimental and theoretical methods. X-ray diffraction, Hirshfeld surface, experimental and ca
Externí odkaz:
https://doaj.org/article/ff480b767516483e942e5f0d0fec1ac3
Autor:
Robert Kubina, Kamil Krzykawski, Arkadiusz Sokal, Marcel Madej, Arkadiusz Dziedzic, Monika Kadela-Tomanek
Publikováno v:
Cells, Vol 12, Iss 18, p 2288 (2023)
Head and neck cancer (HNC) therapy is limited; therefore, new solutions are increasingly being sought among flavonoids, which exhibit numerous biological properties, including potential anticancer activity. However, because they are mostly insoluble
Externí odkaz:
https://doaj.org/article/0506fbe7bfd1450781a1e7ce979304ab
Publikováno v:
Molecules, Vol 28, Iss 18, p 6644 (2023)
One of the most essential health problems is cancer, the first or second cause of death worldwide. Head and neck cancers are hard to detect due to non-specific symptoms. The treatment often relies on a combination of radio and chemotherapy. For this
Externí odkaz:
https://doaj.org/article/484d081610a149bdbb8e16f54f962049