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pro vyhledávání: '"Monika K. Franco"'
Autor:
Joshua D. Jones, Monika K. Franco, Tyler J. Smith, Laura R. Snyder, Anna G. Anders, Brandon T. Ruotolo, Robert T. Kennedy, Kristin S. Koutmou
Publikováno v:
RSC Chemical Biology. 4:363-378
Chemical modifications to protein encoding messenger RNA (mRNA) can modulate their localization, translation and stability within cells. Over 15 different types of mRNA modifications have been identified by sequencing and liquid chromatography couple
Autor:
Monika K. Franco, Kristin S. Koutmou
Publikováno v:
Biophys Chem
Messenger RNAs (mRNAs) serve as blueprints for protein synthesis by the molecular machine the ribosome. The ribosome relies on hydrogen bonding interactions between adaptor aminoacyl-transfer RNA molecules and mRNAs to ensure the rapid and faithful t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474a31a8426bc766e0bf5adcf259da7a
https://europepmc.org/articles/PMC9373004/
https://europepmc.org/articles/PMC9373004/
Autor:
Meredith K. Purchal, Daniel E. Eyler, Mehmet Tardu, Monika K. Franco, Megan M. Korn, Taslima Khan, Ryan McNassor, Rachel Giles, Katherine Lev, Hari Sharma, Jeremy Monroe, Leena Mallik, Markos Koutmos, Kristin S. Koutmou
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Pseudouridine is among the most-abundant RNA modifications. We present a framework for conceptualizing how eukaryotic pseudouridine synthases select their substrates. This work reveals the structure of yeast pseudouridine synthase 7 (Pus
Autor:
Kristin S. Koutmou, Yury S. Polikanov, Daniel E. Eyler, Malgorzata Dobosz-Bartoszek, Bijoyita Roy, Monika K Franco, Joshua D. Jones, Zahra Batool, Monica Z. Wu, Michelle L. Dubuke
Publikováno v:
Proc Natl Acad Sci U S A
Chemical modifications of RNAs have long been established as key modulators of nonprotein-coding RNA structure and function in cells. There is a growing appreciation that messenger RNA (mRNA) sequences responsible for directing protein synthesis can