Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Monika Johar"'
Autor:
Tracey Manning, Dinesh Rai, Babita Agrawal, Naveen C. Srivastav, Monika Johar, Dennis Kunimoto, Rakesh K. Kumar
Publikováno v:
Journal of Medicinal Chemistry. 50:4766-4774
The prevalence of tuberculosis (TB) and mutidrug-resistant tuberculosis (MDR-TB) has been increasing, leading to serious infections, high mortality, and a global health threat. Here, we report the identification of a novel class of dideoxy nucleoside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db747fd093d4efe9a35d52740a19087
https://doi.org/10.1021/jm070391t
https://doi.org/10.1021/jm070391t
Autor:
Nancy Desroches, Tracey Manning, Rakesh K. Kumar, Monika Johar, Christopher Tse, Dennis Kunimoto, Babita Agrawal
Publikováno v:
Journal of Medicinal Chemistry. 50:3696-3705
The resurgence of tuberculosis and the emergence of multiple-drug-resistant strains of Mycobacteria necessitate the search for new classes of antimycobacterial agents. We synthesized a series of 1-beta-D-2'-arabinofuranosyl and 1-(2'-deoxy-2'-fluoro-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bca01aefe0c944393d0b704da3e6166
https://doi.org/10.1021/jm0703901
https://doi.org/10.1021/jm0703901
Publikováno v:
Journal of Medicinal Chemistry. 49:2049-2054
Chronic hepatitis B virus (HBV) infection remains a major health problem worldwide. The main clinical limitation of a current antiviral drug for HBV, lamivudine, is the emergence of drug-resistant viral strains upon prolonged therapy. A group of 5-,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36035b6fb783666790327e886f6cb57
https://doi.org/10.1021/jm058271d
https://doi.org/10.1021/jm058271d
Publikováno v:
Bioorganic & Medicinal Chemistry. 13:6663-6671
Mycobacterium tuberculosis and Mycobacterium avium infections cause the two most important mycobacterioses, leading to increased mortality in patients with AIDS. Various 5-substituted 2'-deoxyuridines, uridines, 2'-O-methyluridine, 2'-ribofluoro-2'-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc385538376245e4695d41c1aa22beae
https://doi.org/10.1016/j.bmc.2005.07.046
https://doi.org/10.1016/j.bmc.2005.07.046
Publikováno v:
Bioorganic & Medicinal Chemistry. 13:6158-6166
3-Aminobenzonitrile and 2-amino-4-phenyl thiazole on condensation with 4-isothiocyanato-4-methyl pentane-2-one gave condensed monocyclic pyrimidine derivatives 1 and 2, 3, respectively. Condensation of 3-aminopropyl imidazole with 3-isothiocyantobuta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8567b770265d7203110f4cb02617d6e5
https://doi.org/10.1016/j.bmc.2005.06.063
https://doi.org/10.1016/j.bmc.2005.06.063
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 174:81-92
The reactions of substituted o-phenylene diamines, o-aminophenol, o-aminothiophenol, 3,4-diaminopyridine with p-cyanobenzaldehyde by refluxing in nitrobenzene gave corresponding benzimidazole, benzoxazole, benzthiazole and imidazopyridine derivatives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::650f368e9d717e8d907f018adfe39ed0
https://doi.org/10.1080/10426500108040234
https://doi.org/10.1080/10426500108040234
Autor:
Ram Raghubir, Nidhi Singhal, Rakesh Shukla, Sunanda G. Dastidar, Monika Johar, Sham M. Sondhi
Publikováno v:
Monatshefte für Chemie/Chemical Monthly. 131:0511-0520
Various sulfa drugs were condensed with 4-isothiocyanato-4-methyl-2-pentanone at pH∼3–5 by refluxing in methanol to give various substituted mercaptopyrimidines. On condensation with 9-chloro-2-substituted or -unsubstituted acridines, sulfathiazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bd07aa32b347ba7c41e13f221a85534
https://doi.org/10.1007/s007060050332
https://doi.org/10.1007/s007060050332
Autor:
Nidhi Singhal, Ram Raghubir, Rakesh Shukla, Sham M. Sondhi, Monika Johar, Sunanda G. Dastidar
Publikováno v:
ChemInform. 31
Various sulfa drugs were condensed with 4-isothiocyanato-4-methyl-2-pentanone at pH∼3–5 by refluxing in methanol to give various substituted mercaptopyrimidines. On condensation with 9-chloro-2-substituted or -unsubstituted acridines, sulfathiazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e00586989393a38e9cf0700c4bd4b15
https://doi.org/10.1002/chin.200036152
https://doi.org/10.1002/chin.200036152
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91b6d77af090c5ee697814da37a23171
https://doi.org/10.1002/chin.200225145
https://doi.org/10.1002/chin.200225145
Publikováno v:
ChemInform. 33
Sulphamerazine, sulphadiazine, and sulphaguanidine are coupled with hemin to give bis coupled products la, 1b and 1c respectively. 3, 4-Diphenyl iminothiazoline, sulphamerazine, sulphaacetamide, sulphathiazole and sulphadiazine on coupling with hemat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af25ec108144fd23a945af26bb2d8aca
https://doi.org/10.1002/chin.200218114
https://doi.org/10.1002/chin.200218114