Microarray analysis of LTR retrotransposon silencing identifies Hdac1 as a regulator of retrotransposon expression in mouse embryonic stem cells.

Autor: Judith Reichmann, James H Crichton, Monika J Madej, Mary Taggart, Philippe Gautier, Jose Luis Garcia-Perez, Richard R Meehan, Ian R Adams

Publikováno v: PLoS Computational Biology, Vol 8, Iss 4, p e1002486 (2012)

Retrotransposons are highly prevalent in mammalian genomes due to their ability to amplify in pluripotent cells or developing germ cells. Host mechanisms that silence retrotransposons in germ cells and pluripotent cells are important for limiting the

Externí odkaz: https://doaj.org/article/9cb08067b1cb491f9e1ed71868614125

Microarray analysis of LTR retrotransposon silencing identifies Hdac1 as a regulator of retrotransposon expression in mouse embryonic stem cells

Autor: Jose L. Garcia-Perez, Ian R. Adams, Philippe Gautier, James H. Crichton, Mary Taggart, Richard R. Meehan, Monika J. Madej, Judith Reichmann

Publikováno v: PLoS Computational Biology, Vol 8, Iss 4, p e1002486 (2012)
Reichmann, J, Crichton, J H, Madej, M J, Taggart, M, Gautier, P, Garcia-Perez, J, Meehan, R & Adams, I R 2012, ' Microarray analysis of LTR retrotransposon silencing identifies Hdac1 as a regulator of retrotransposon expression in mouse embryonic stem cells ', PLoS Computational Biology, vol. 8, no. 4, e1002486 . https://doi.org/10.1371/journal.pcbi.1002486
PLoS Computational Biology

Retrotransposons are highly prevalent in mammalian genomes due to their ability to amplify in pluripotent cells or developing germ cells. Host mechanisms that silence retrotransposons in germ cells and pluripotent cells are important for limiting the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f875106402bdcb8f39652ca9d3da7b
http://europepmc.org/articles/PMC3343110?pdf=render

The interaction of xKaiso with xTcf3:a revised model for integration of epigenetic and Wnt signalling pathways

Autor: Egor Prokhortchouk, James P. Reddington, Monika J. Madej, Donncha S. Dunican, Jamie A. Hackett, Anna Prokhortchouk, Richard R. Meehan, Sari Pennings, Alexey Ruzov

Publikováno v: Ruzov, A, Hackett, J A, Prokhortchouk, A, Reddington, J P, Madej, M J, Dunican, D S, Prokhortchouk, E, Pennings, S & Meehan, R R 2009, ' The interaction of xKaiso with xTcf3 : a revised model for integration of epigenetic and Wnt signalling pathways ', Development, vol. 136, no. 5, pp. 723-727 . https://doi.org/10.1242/dev.025577

We demonstrate that a direct interaction between the methyl-CpG-dependent transcription repressor Kaiso and xTcf3, a transducer of the Wnt signalling pathway, results in their mutual disengagement from their respective DNA-binding sites. Thus, the tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7892bfde4bbbf99eaf641c88f92fed1a
https://hdl.handle.net/20.500.11820/52832e10-f7ce-453b-885d-07e45bf25ebf

Detection of small RNAs in Pseudomonas aeruginosa by RNomics and structure-based bioinformatic tools

Autor: Sven Findeiss, Udo Bläsi, Peter F. Stadler, Isabella Moll, Elisabeth Sonnleitner, Monika J. Madej, Jörg Hackermüller, Alexander Hüttenhofer, Theresa Sorger-Domenigg

Inactivation of the Pseudomonas aeruginosa (PAO1) hfq gene, encoding the Sm-like Hfq protein, resulted in pleiotropic effects that included an attenuated virulence. As regulation by Hfq often involves the action of small regulatory RNAs (sRNAs), we h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abef1524cddcbc22035feded86f8ab0
https://publica.fraunhofer.de/handle/publica/217144

Identification of small non-coding RNAs from mitochondria and chloroplasts

Autor: Birgit Lung, Anja Zemann, Monika J. Madej, Stephanie Ruf, Sandra Techritz, Markus Schuelke, Ralph Bock, Alexander Hüttenhofer

Publikováno v: Nucleic Acids Research

Small non-protein-coding RNAs (ncRNAs) have been identified in a wide spectrum of organisms ranging from bacteria to humans. In eukarya, systematic searches for ncRNAs have so far been restricted to the nuclear or cytosolic compartments of cells. Whe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bfef6f9270c376eaaa32c365e98184
https://hdl.handle.net/11858/00-001M-0000-0014-2A13-F11858/00-001M-0000-0014-2A11-4