Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Monika Huszar"'
Autor:
Marina M. Carrozzo, Lucie Hartmanova, Monika Huszar, Wolfgang Lindner, Peter Frühauf, Roland Reischl
Publikováno v:
Journal of Chromatography A. 1218:8379-8387
D-Amino acid analysis in biological samples still poses a challenge to analytical chemists. In higher developed species trace amounts of d-amino acids have to be detected in vast excesses of the corresponding L-enantiomers. This method utilizes an ea
Autor:
Tibor Vántus, T. Lorand, Attila Varga, M. Idei, Attila Agócs, Anikó Horváth, József Mandl, Gy. Kéri, Monika Huszar
Publikováno v:
Current Medicinal Chemistry. 17:321-333
Compound lipophilicity connected to ADME(T)(a) has great importance in drug development and it has to be evaluated by the generally used drug developmental process. In addition to the importance of lipophilicity in ADMET, recently it has been reporte
Autor:
Yaron Carmi, Shahar Dotan, Malka R. White, Michal A. Rahat, Monika Huszar, Mina Fogel, Ron N. Apte, Elena Voronov, Nitza Lahat, Charles A. Dinarello
Publikováno v:
The Journal of Immunology. 183:4705-4714
Inflammation and angiogenesis are pivotal processes in the progression of many diseases, including malignancies. A hypoxic microenvironment often results in a milieu of proinflammatory and proangiogenic cytokines produced by infiltrating cells. We as
Publikováno v:
Journal of the American Academy of Dermatology. 57:669-676
The evolution of squamous cell carcinoma (SCC) on sun-exposed areas is a multistep process triggered by ultraviolet radiation (UVR), in which precursor lesions exist. However, the exact classification of the various lesions in this process, mainly so
Autor:
Shraga Segal, Yoichiro Iwakura, Shahar Dotan, Elena Voronov, Charles A. Dinarello, Ron N. Apte, Monika Huszar, Yakov Krelin, Eli Reich, Moshe Elkabets, Mina Fogel
Publikováno v:
Cancer Research. 67:1062-1071
The role of microenvironment interleukin 1 (IL-1) on 3-methylcholanthrene (3-MCA)–induced carcinogenesis was assessed in IL-1–deficient mice, i.e., IL-1β−/−, IL-1α−/−, IL-1α/β−/− (double knockout), and mice deficient in the natura
Publikováno v:
The American Journal of Dermatopathology. 27:1-5
Pseudorheumatoid nodules are considered a deep form of granuloma annulare. Most cases are described in children, occur mainly on the lower legs and scalp, and have favorable prognosis. Their appearance in adults is rare. In this series, fourteen wome
Publikováno v:
The American Journal of Dermatopathology. 26:372-378
The E-cadherin-beta-catenin complex regulates the architectural integrity of epithelia by mediating intercellular adhesion. Down-regulation of its expression may contribute to invasion and metastatic behavior of carcinoma cells. Several studies demon
Autor:
Ferenc Baska, György Kéri, László Hunyady, Zoltán Varga, Péter Markó, Nóra Breza, Monika Huszar, Zoltán Horváth, Tibor Vántus, László Buday, Laszlo Orfi, Gabor Borbely, István Szabadkai, Miklós Geiszt
Publikováno v:
Journal of medicinal chemistry. 53(18)
NOX enzymes are the major contributors in many oxidative damage related diseases. Unfortunately, at present no specific NOX inhibitor is available. Here, we describe the discovery and development of novel NOX4 inhibitors. Compound libraries were test
Autor:
Fabrice Benchetrit, Yakov Krelin, Lubov Gayvoronsky, Ron N. Apte, Moshe Elkabets, Rosalyn M. White, Monika Huszar, Idan Cohen, Shahar Dotan, Joseph El-On, Elena Voronov
Publikováno v:
International immunology. 22(4)
The role of host-derived IL-1 on the course of Leishmania major infection in susceptible BALB/c mice was assessed. Manifestations of the disease were more severe in mice deficient in the physiological inhibitor of IL-1, the IL-1 receptor antagonist (
Autor:
Marc Beer-Gabel, Michal Kori, Valeri Gladish, Monika Huszar, Nadia Ziv-Sokolovskaya, Ram Reifen
Publikováno v:
Journal of clinical gastroenterology. 37(1)
Goals: To determine the significance of performing routine duodenal biopsies during upper intestinal endoscopy in a pediatric population and to evaluate their contribution to the overall diagnosis. Background: Performing duodenal biopsy during every