Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Monika Gronemeier"'
Publikováno v:
Progress in Neurobiology. 42:313-317
Any biological structure can be studied using mutations that interfere either with its emergence or its function. We investigate spontaneous and induced mutations in the mouse that affect neuromuscular development and function. The wobbler mouse (phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e35afa8e381ee31dad92c80b4cdcda
https://doi.org/10.1016/0301-0082(94)90071-x
https://doi.org/10.1016/0301-0082(94)90071-x
Autor:
Harald Jockusch, Steven L. Roberds, Monika Gronemeier, Barbara Albrecht, Michael M. Tamkun, Olaf Pongs, Rainer Klocke, André Augustin
Publikováno v:
Genomics. 18:568-574
The four Shaker -like subfamilies of Shaker-, Shab-,Shaw- , and Shal -related K + channels in mammals have been defined on the basis of their sequence homologies to the corresponding Drosophila genes. Using interspecific backcrosses between Mus muscu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0e2164e570e7b1dbe78e2d906deda9
https://doi.org/10.1016/s0888-7543(05)80358-1
https://doi.org/10.1016/s0888-7543(05)80358-1
Autor:
Harald Jockusch, Christoph Ortland, Stefan Gründer, Klaus Steinmeyer, Monika Gronemeier, Thomas J. Jentsch, Rainer Klocke
Publikováno v:
Nature. 354:304-308
MYOTONIA (stiffness and impaired relaxation of skeletal muscle) is a symptom of several diseases caused by repetitive firing of action potentials in muscle membranes 1. Purely myotonic human diseases are dominant myotonia congenita (Thomsen) and rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105d236799577f84b10d00ba17274712
https://doi.org/10.1038/354304a0
https://doi.org/10.1038/354304a0
Autor:
Niels Wedemeyer, Olga Antropova, Monika Gronemeier, Volker Schnülle, Jörg W. Bartsch, Harald Jockusch
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 8(10)
Myotonias are muscle diseases in which the function of the muscular chloride channel ClC-1 is impaired. Null alleles of the corresponding Clc1 gene on mouse chromosome (Chr) 6 provide animal models for human myotonias. It was shown that the allele ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd40c4e9cf40c236f8f51a285cddf57
https://pubmed.ncbi.nlm.nih.gov/9321463
https://pubmed.ncbi.nlm.nih.gov/9321463
Autor:
Monika Gronemeier, Thomas J. Jentsch, Melanie Ronsiek, Andreas Lengeling, Astrid Thiemann, Harald Jockusch
Publikováno v:
Europe PubMed Central
SummaryTheClc2gene of the mouse codes for the ubiquitously expressed chloride channel ClC-2, a member of a family of at least seven voltage gated chloride channels, some of which are implicated in hereditary diseases. Using a mouse interspecies back-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189aaeae153c7111a03a96ae4671206d
https://pubmed.ncbi.nlm.nih.gov/8522159
https://pubmed.ncbi.nlm.nih.gov/8522159
Publikováno v:
Europe PubMed Central
In mature vertebrate muscle, the chloride channel Clc-1 is necessary for the stabilization of the resting potential. Its functional defect leads to the disease myotonia. The ADR mouse (phenotype ADR, genotype adr/adr) is an animal model for human myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689fa65d5f514c2bc50fc9cc059d3e00
http://europepmc.org/abstract/med/8119941
http://europepmc.org/abstract/med/8119941
