Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Monika Golinska"'
Autor:
Vanessa Zancanella, Astrid Vallès, Jolanda M.P. Liefhebber, Lieke Paerels, Carlos Vendrell Tornero, Hendrina Wattimury, Tom van der Zon, Kristel van Rooijen, Monika Golinska, Tamar Grevelink, Erich Ehlert, Elsbet Jantine Pieterman, Nanda Keijzer, Hans Marinus Gerardus Princen, Geurt Stokman, Ying Poi Liu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102189- (2024)
Externí odkaz:
https://doaj.org/article/6fce894ae2cc4820930f11537ace45e7
Autor:
Vanessa Zancanella, Astrid Vallès, Jolanda M.P. Liefhebber, Lieke Paerels, Carlos Vendrell Tornero, Hendrina Wattimury, Tom van der Zon, Kristel van Rooijen, Monika Golinska, Tamar Grevelink, Erich Ehlert, Elsbet Jantine Pieterman, Nanda Keijzer, Hans Marinus Gerardus Princen, Geurt Stokman, Ying Poi Liu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 454-467 (2023)
A gene-silencing platform (miQURE) has been developed and successfully used to deliver therapeutic microRNA (miRNA) to the brain, reducing levels of neurodegenerative disease-causing proteins/RNAs via RNA interference and improving the disease phenot
Externí odkaz:
https://doaj.org/article/0d8c24346e504114948232885b1d3acd
Publikováno v:
Cells, Vol 10, Iss 9, p 2371 (2021)
In solid tumours, cancer cells exist within hypoxic microenvironments, and their metabolic adaptation to this hypoxia is driven by HIF-1 transcription factor, which is overexpressed in a broad range of human cancers. HIF inhibitors are under pre-clin
Externí odkaz:
https://doaj.org/article/a985d9e37270413e9fc8e6a34b230116
Publikováno v:
Cells
Cells, Vol 10, Iss 2371, p 2371 (2021)
Cells, Vol 10, Iss 2371, p 2371 (2021)
In solid tumours, cancer cells exist within hypoxic microenvironments, and their metabolic adaptation to this hypoxia is driven by HIF-1 transcription factor, which is overexpressed in a broad range of human cancers. HIF inhibitors are under pre-clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde4ee1337671fc91e5c6ffc6f6e3a8e
Autor:
Lucy Ly, John R. Griffiths, Helen Troy, Manuel Mayr, Marion Stubbs, Meg Perumal, Paul M.J. McSheehy, Kaye J. Williams, David Perrett, Monika Golinska, John R. Latigo, Adrian L. Harris, Yuen-Li Chung, Rachel Airley, Eric O. Aboagye, Xiaoke Yin
Publikováno v:
BMC Cancer
BMC Cancer, Vol 11, Iss 1, p 198 (2011)
BMC Cancer, Vol 11, Iss 1, p 198 (2011)
Background HIF-1 deficiency has marked effects on tumour glycolysis and growth. We therefore investigated the consequences of HIF-1 deficiency in mice, using the well established Hepa-1 wild-type (WT) and HIF-1β-deficient (c4) model. These mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c5f8dd8c8838a413fc38b234bcbf8d
https://ora.ox.ac.uk/objects/uuid:26b7ef33-0a0c-4870-a363-ea1361e183a2
https://ora.ox.ac.uk/objects/uuid:26b7ef33-0a0c-4870-a363-ea1361e183a2