A novel model of chronic wounds: importance of redox imbalance and biofilm-forming bacteria for establishment of chronicity.

Autor: Sandeep Dhall, Danh Do, Monika Garcia, Dayanjan Shanaka Wijesinghe, Angela Brandon, Jane Kim, Antonio Sanchez, Julia Lyubovitsky, Sean Gallagher, Eugene A Nothnagel, Charles E Chalfant, Rakesh P Patel, Neal Schiller, Manuela Martins-Green

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e109848 (2014)

Chronic wounds have a large impact on health, affecting ∼6.5 M people and costing ∼$25B/year in the US alone. We previously discovered that a genetically modified mouse model displays impaired healing similar to problematic wounds in humans and t

Externí odkaz: https://doaj.org/article/488f8635d5f54f0f98203b86b252303e

Generating and Reversing Chronic Wounds in Diabetic Mice by Manipulating Wound Redox Parameters

Autor: Sandeep Dhall, Danh C. Do, Monika Garcia, Jane Kim, Seyed H. Mirebrahim, Julia Lyubovitsky, Stefano Lonardi, Eugene A. Nothnagel, Neal Schiller, Manuela Martins-Green

Publikováno v: Journal of Diabetes Research, Vol 2014 (2014)

By 2025, more than 500 M people worldwide will suffer from diabetes; 125 M will develop foot ulcer(s) and 20 M will undergo an amputation, creating a major health problem. Understanding how these wounds become chronic will provide insights to reverse

Externí odkaz: https://doaj.org/article/dd5e61ed62694b9fa448ea5bd760861a

1501-P: Patients with Diabetes Mellitus Hospitalized with Pancreatitis Have Reduced Mortality but Higher Overall Cost Compared with Patients without Diabetes

Autor: Matthew Firek, Bishoy Zakhary, Christian S. Jackson, Daniel I. Kim, Anthony Firek, Monika Garcia, Nicole Choi

Publikováno v: Diabetes. 69

Introduction: Acute pancreatitis (AP) is the leading cause of admissions for gastrointestinal disorders in the United States with annual costs of nearly $2.6 billion. The identification of modifiable risk factors may help lower AP-related hospitaliza

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf79bb91a0baa771a66214fb8edeecdb
https://doi.org/10.2337/db20-1501-p

Hybrid Aortic Arch Debranching and TEVAR is Safe in a Private, Community Hospital

Autor: Monika Garcia, G. Lara, H. Nurick, S. Biswas, N. Wong, I. Andacheh

Publikováno v: Annals of Vascular Surgery. 51:278

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa95017b875441e9cad20cee85d281f8
https://doi.org/10.1016/j.avsg.2018.05.020

Release of insulin from PLGA-alginate dressing stimulates regenerative healing of burn wounds in rats

Autor: Manuela Martins-Green, Sandeep Dhall, Ronald J. Neufeld, Monika Garcia, João Pedro Silva, Alex Chan, Julia G. Lyubovitsky, Yan Liu, Michael Hrynyk

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Clinical science (London, England : 1979), vol 129, iss 12

Burn wound healing involves a complex set of overlapping processes in an environment conducive to ischemia, inflammation, and infection costing $7.5 billion/year in the US alone, in addition to the morbidity and mortality that occur when the burns ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd06c0be977b08d50a19159c1a6e7d4
https://hdl.handle.net/1822/38236