Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Monika Fijak"'
Autor:
Christiane Pleuger, Dingding Ai, Minea L Hoppe, Laura T Winter, Daniel Bohnert, Dominik Karl, Stefan Guenther, Slava Epelman, Crystal Kantores, Monika Fijak, Sarina Ravens, Ralf Middendorff, Johannes U Mayer, Kate L Loveland, Mark Hedger, Sudhanshu Bhushan, Andreas Meinhardt
Publikováno v:
eLife, Vol 11 (2022)
The epididymis functions as transition zone for post-testicular sperm maturation and storage and faces contrasting immunological challenges, i.e. tolerance towards spermatozoa vs. reactivity against pathogens. Thus, normal organ function and integrit
Externí odkaz:
https://doaj.org/article/a41d07b05a714c4997aefbc4d9a009e5
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Infection and inflammation are relevant entities of male reproductive disorders that can lead to sub-/infertility. Associated damage of the testis of affected men and in rodent models include leukocytic infiltration, edema formation, fibrosis, germ c
Externí odkaz:
https://doaj.org/article/dcd89e9402ac49a9bdaad26178fad3b7
Autor:
Sudhanshu Bhushan, María S. Theas, Vanesa A. Guazzone, Patricia Jacobo, Ming Wang, Monika Fijak, Andreas Meinhardt, Livia Lustig
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Immunoregulation in the testis is characterized by a balance between immuno-suppression (or immune privilege) and the ability to react to infections and inflammation. In this review, we analyze the phenotypes of the various immune cell subtypes prese
Externí odkaz:
https://doaj.org/article/0886365ccb164b72829fb9cf131dabf7
Autor:
Livia Lustig, Vanesa A. Guazzone, María S. Theas, Christiane Pleuger, Patricia Jacobo, Cecilia V. Pérez, Andreas Meinhardt, Monika Fijak
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Infection and inflammation of the male reproductive tract are relevant causes of infertility. Inflammatory damage occurs in the special immunosuppressive microenvironment of the testis, a hallmark termed testicular immune privilege, which allows tole
Externí odkaz:
https://doaj.org/article/84ba72bf5e4d4a4b8282c42d7a64da5b
Autor:
Wei Peng, Artem Kepsch, Till O. Kracht, Hiba Hasan, Rukmali Wijayarathna, Eva Wahle, Christiane Pleuger, Sudhanshu Bhushan, Stefan Günther, A. Christine Kauerhof, Ana Planinić, Daniela Fietz, Hans-Christian Schuppe, Małgorzata Wygrecka, Kate L. Loveland, Davor Ježek, Andreas Meinhardt, Mark P. Hedger, Monika Fijak
Publikováno v:
Cellular and Molecular Life Sciences. 79
Experimental autoimmune-orchitis (EAO), a rodent model of chronic testicular inflammation and fibrosis, replicates pathogenic changes seen in some cases of human spermatogenic disturbances. During EAO, increased levels of pro-inflammatory and pro-fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1210b7391724be69510ed8c4e7ce5214
https://doi.org/10.1007/s00018-022-04632-4
https://doi.org/10.1007/s00018-022-04632-4
Autor:
Christiane Pleuger, Dingding Ai, Minea L Hoppe, Laura T Winter, Daniel Bohnert, Dominik Karl, Stefan Guenther, Slava Epelman, Crystal Kantores, Monika Fijak, Sarina Ravens, Ralf Middendorff, Johannes U Mayer, Kate L Loveland, Mark Hedger, Sudhanshu Bhushan, Andreas Meinhardt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85237a60799a41e45bb480a6cf2dca70
https://doi.org/10.7554/elife.82193.sa2
https://doi.org/10.7554/elife.82193.sa2
Autor:
Tao Lei, Sandra M. Blois, Stefan A. Wudy, Fu-Tong Liu, Sudhanshu Bhushan, Andreas Meinhardt, Annie Chi-Chun Huang, Michaela F. Hartmann, Martin Bergmann, Monika Fijak, Hung-Lin Chen, Nancy Freitag, Eva Wahle
Publikováno v:
Cellular and Molecular Life Sciences. 78:3621-3635
Galectin 3 is a multifunctional lectin implicated in cellular proliferation, differentiation, adhesion, and apoptosis. This lectin is broadly expressed in testicular somatic cells and germ cells, and is upregulated during testicular development. Sinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b1d87051572725a50d5a4c93d3c7788
https://doi.org/10.1007/s00018-021-03757-2
https://doi.org/10.1007/s00018-021-03757-2
Autor:
Elena, Berg, Petr, Houska, Nils, Nesheim, Hans-Christian, Schuppe, Adrian, Pilatz, Monika, Fijak, Marc, Manthey, Klaus, Steger, Florian, Wagenlehner, Undraga, Schagdarsurengin
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7854, p 7854 (2021)
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7854, p 7854 (2021)
Background: Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a frequent disease affecting men of every age and accounting for a great number of consultations at urology departments. Previous studies suggested a negative impact of CP/CPPS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d07dc4ce68e009d5ffe1c0e14e77eca8
Autor:
Fabian Hemm, Monika Fijak, Jan Belikan, Marian Kampschulte, Thaqif El Khassawna, Adrian Pilatz, Christian Heiss, Katrin Susanne Lips
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7858, p 7858 (2021)
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7858, p 7858 (2021)
Investigations in male patients with fertility disorders revealed a greater risk of osteoporosis. The rodent model of experimental autoimmune-orchitis (EAO) was established to analyze the underlying mechanisms of male infertility and causes of reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::605ae58b35b7950d644a9047bddd67f4
http://europepmc.org/articles/PMC8346031
http://europepmc.org/articles/PMC8346031
Autor:
A. Christine Kauerhof, Mark P. Hedger, Adrian Pilatz, Hans-Christian Schuppe, Sabine Kliesch, Daniela Fietz, Kate A. Loveland, Sudhanshu Bhushan, Nour Nicolas, Eva Wahle, Nigel P. Groome, Martin Bergmann, Andreas Meinhardt, Monika Fijak
Publikováno v:
Human Reproduction. 34:1536-1550
STUDY QUESTION Does activin A contribute to testicular fibrosis under inflammatory conditions? SUMMARY ANSWER Our results show that activin A and key fibrotic proteins are increased in human testicular biopsies with leukocytic infiltrates and impaire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d994131281fe9a0c34247de084618145
https://doi.org/10.1093/humrep/dez109
https://doi.org/10.1093/humrep/dez109