Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Monika Denk"'
Autor:
Susanne Jung, Annika Nelde, Yacine Maringer, Monika Denk, Lisa Zieschang, Christine Kammer, Melek Özbek, Peter Martus, Christopher Hackenbruch, Alexander Englisch, Jonas S. Heitmann, Helmut R. Salih, Juliane S. Walz
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionAcute myeloid leukemia (AML) has a dismal prognosis, mostly due to minimal residual disease-driven relapse, making an elimination of persisting therapy-resistant leukemia progenitor/stem cells (LPCs) the main goal for novel therapies. Pep
Externí odkaz:
https://doaj.org/article/4ad85c4b3c4a4a858a9ec662b89e13e5
Autor:
Alexander Englisch, Clara Hayn, Susanne Jung, Jonas S. Heitmann, Christopher Hackenbruch, Yacine Maringer, Annika Nelde, Marcel Wacker, Monika Denk, Lisa Zieschang, Christine Kammer, Peter Martus, Helmut R. Salih, Juliane S. Walz
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Chronic lymphocytic leukemia (CLL) is the most common form of leukemia among adults in Western countries. Despite the introduction of targeted therapies, including first-line Bruton’s tyrosine kinase inhibitor (BTKi) treatment, CLL remains largely
Externí odkaz:
https://doaj.org/article/dd7432dd452f4e3c895e7e3e1fbf5b55
Autor:
Claudia Tandler, Jonas S. Heitmann, Tanja M. Michel, Maddalena Marconato, Simon U. Jaeger, Christian M. Tegeler, Monika Denk, Marion Richter, Melek Tutku Oezbek, Yacine Maringer, Sarah M. Schroeder, Nicole Schneiderhan-Marra, Karl-Heinz Wiesmüller, Michael Bitzer, Natalia Ruetalo, Michael Schindler, Christoph Meisner, Imma Fischer, Hans-Georg Rammensee, Helmut R. Salih, Juliane S. Walz
Publikováno v:
International Journal of Infectious Diseases, Vol 139, Iss , Pp 69-77 (2024)
Objectives: T cell immunity is key for the control of viral infections including SARS-CoV-2, in particular with regard to immune memory and protection against arising genetic variants. Methods: We recently evaluated a peptide-based SARS-CoV-2 T cell
Externí odkaz:
https://doaj.org/article/c354f5fd26fd421f8230c3f45d62af98
Autor:
Christopher Hackenbruch, Jens Bauer, Jonas S. Heitmann, Yacine Maringer, Annika Nelde, Monika Denk, Lisa Zieschang, Christine Kammer, Birgit Federmann, Susanne Jung, Peter Martus, Nisar P. Malek, Konstantin Nikolaou, Helmut R. Salih, Michael Bitzer, Juliane S. Walz
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The DNAJB1-PRKACA fusion transcript was identified as the oncogenic driver of tumor pathogenesis in fibrolamellar hepatocellular carcinoma (FL-HCC), also known as fibrolamellar carcinoma (FLC), as well as in other tumor entities, thus representing a
Externí odkaz:
https://doaj.org/article/a2dd1647213e47a0b299877dea3ea6f4
Autor:
Niklas Grassl, Katharina Sahm, Heike Süße, Isabel Poschke, Lukas Bunse, Theresa Bunse, Tamara Boschert, Iris Mildenberger, Anne-Kathleen Rupp, Max Philipp Ewinger, Lisa-Marie Lanz, Monika Denk, Ghazaleh Tabatabai, Michael W. Ronellenfitsch, Ulrich Herrlinger, Martin Glas, Dietmar Krex, Peter Vajkoczy, Antje Wick, Inga Harting, Felix Sahm, Andreas von Deimling, Martin Bendszus, Wolfgang Wick, Michael Platten
Publikováno v:
Neurological Research and Practice, Vol 5, Iss 1, Pp 1-6 (2023)
Abstract Introduction Diffuse midline gliomas (DMG) are universally lethal central nervous system tumors that carry almost unanimously the clonal driver mutation histone-3 K27M (H3K27M). The single amino acid substitution of lysine to methionine harb
Externí odkaz:
https://doaj.org/article/968882c501c548889b7af8e6c08a2e21
Autor:
Jonas S. Heitmann, Claudia Tandler, Maddalena Marconato, Annika Nelde, Timorshah Habibzada, Susanne M. Rittig, Christian M. Tegeler, Yacine Maringer, Simon U. Jaeger, Monika Denk, Marion Richter, Melek T. Oezbek, Karl-Heinz Wiesmüller, Jens Bauer, Jonas Rieth, Marcel Wacker, Sarah M. Schroeder, Naomi Hoenisch Gravel, Jonas Scheid, Melanie Märklin, Annika Henrich, Boris Klimovich, Kim L. Clar, Martina Lutz, Samuel Holzmayer, Sebastian Hörber, Andreas Peter, Christoph Meisner, Imma Fischer, Markus W. Löffler, Caroline Anna Peuker, Stefan Habringer, Thorsten O. Goetze, Elke Jäger, Hans-Georg Rammensee, Helmut R. Salih, Juliane S. Walz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract T-cell immunity is central for control of COVID-19, particularly in patients incapable of mounting antibody responses. CoVac-1 is a peptide-based T-cell activator composed of SARS-CoV-2 epitopes with documented favorable safety profile and e
Externí odkaz:
https://doaj.org/article/b32dbe5fcabf453983d2e107f672acc4
Autor:
Jens Bauer, Natalie Köhler, Yacine Maringer, Philip Bucher, Tatjana Bilich, Melissa Zwick, Severin Dicks, Annika Nelde, Marissa Dubbelaar, Jonas Scheid, Marcel Wacker, Jonas S. Heitmann, Sarah Schroeder, Jonas Rieth, Monika Denk, Marion Richter, Reinhild Klein, Irina Bonzheim, Julia Luibrand, Ursula Holzer, Martin Ebinger, Ines B. Brecht, Michael Bitzer, Melanie Boerries, Judith Feucht, Helmut R. Salih, Hans-Georg Rammensee, Stephan Hailfinger, Juliane S. Walz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The DNAJB1-PRKACA fusion transcript is the oncogenic driver in fibrolamellar hepatocellular carcinoma, a lethal disease with limited therapeutic options. Here, the authors identify the DNAJB1-PRKACA protein as a source for immunogenic neoepitopes and
Externí odkaz:
https://doaj.org/article/3a134c49c74b482cbf740f80cccba049
Autor:
Lukas Bunse, Anne-Kathleen Rupp, Isabel Poschke, Theresa Bunse, Katharina Lindner, Antje Wick, Jens Blobner, Martin Misch, Ghazaleh Tabatabai, Martin Glas, Oliver Schnell, Jens Gempt, Monika Denk, Guido Reifenberger, Martin Bendszus, Patrick Wuchter, Joachim P Steinbach, Wolfgang Wick, Michael Platten
Publikováno v:
Neurological Research and Practice, Vol 4, Iss 1, Pp 1-7 (2022)
Abstract Introduction Isocitrate dehydrogenase (IDH) mutations are disease-defining mutations in IDH-mutant astrocytomas and IDH-mutant and 1p/19q-codeleted oligodendrogliomas. In more than 80% of these tumors, point mutations in IDH type 1 (IDH1) le
Externí odkaz:
https://doaj.org/article/4c9969cb47df44d0813e1eae513b7e2a
Autor:
Simon Jäger, Juliane S. Walz, Jonas Rieth, Markus W. Löffler, Sebastian Hörber, Reinhild Klein, Julia Karbach, Christoph Meisner, Leonard Anton, Monika Denk, Hans-Georg Rammensee, Annika Nelde, Julia Reusch, Imma Fischer, Lisa Marie Weber, Elke Jäger, Jonas S. Heitmann, Maddalena Marconato, Claudia Tandler, Malte Roerden, Marcel Wacker, Andreas Peter, Jens Bauer, Helmut R. Salih, Marion Richter, Yacine Maringer, Tatjana Bilich
Publikováno v:
Nature
T cell immunity is central for the control of viral infections. CoVac-1 is a peptide-based vaccine candidate, composed of SARS-CoV-2 T cell epitopes derived from various viral proteins1,2, combined with the Toll-like receptor 1/2 agonist XS15 emulsif
Autor:
Juliane Walz, Jonas Heitmann, Claudia Tandler, Maddalena Marconato, Timursah Habibzade, Susanne Rittig, Christian Tegeler, Annika Nelde, Yacine Maringer, Simon Jäger, Monika Denk, Marion Richter, Melek Oezbek, Karl-Heinz Wiesmüller, Jens Bauer, Jonas Rieth, Marcel Wacker, Sarah Schroeder, Naomi Hoenisch Gravel, Melanie Märklin, Annika Henrich, Boris Klimovich, Kim Clar, Martina Lutz, Samuel Holzmayer, Sebastian Hoerber, Andreas Peter, Christoph Meisner, Imma Fischer, Markus Löffler, Caroline Peuker, Stefan Habringer, Thorsten Goetze, Elke Jäger, Hans-Georg Rammensee, Helmut Salih
T-cell immunity is central for the control of COVID-19, in particular in patients incapable to mount a humoral immune response. We previously reported on the favorable safety profile and efficacy in terms of induction of SARS-CoV-2-specific T-cell re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11dacecc552fc88bf0c7d34ea2030f3a
https://doi.org/10.21203/rs.3.rs-1693355/v1
https://doi.org/10.21203/rs.3.rs-1693355/v1