Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Monika Franz"'
Autor:
Tina Schultheiss, Sophia G. Antimisiaris, Richard Storer, Roberta Loddo, Christophe Parsy, Nicole Stolte-Leeb, Ulrike Sauermann, Paolo La Colla, Christiane Stahl-Hennig, Monika Franz, Spyridon Mourtas
Publikováno v:
AIDS Research and Human Retroviruses. 27:933-943
The availability of an effective vaginal microbicide would be a major step toward containment of HIV transmission as well as allowing women self-protection against HIV infection. Here we evaluated the efficacy of vaginal application of the potent non
Autor:
Young Chul Sung, Ulrike Sauermann, Klaus Überla, Ki Seok Park, Ralph M. Steinman, Christiane Stahl-Hennig, Stephen Norley, Seraphin Kuate, You Suk Suh, Monika Franz, Heribert Stoiber, Klara Tenner-Racz, Paul Racz
Publikováno v:
Journal of Virology. 81:13180-13190
The development of needle-free vaccines is one of the recently defined “grand challenges in global health” (H. Varmus, R. Klausner, R. Klausner, R. Zerhouni, T. Acharya, A. S. Daar, and P. A. Singer, Science 302:398-399, 2003). To explore whether
Autor:
Monika Franz, Ralf Wagner, Ralf Ignatius, Seraphin Kuate, S. Norley, Ulrike Sauermann, Anja Floto, Ralph M. Steinman, Paul Racz, Heribert Stoiber, Christiane Stahl-Hennig, Simon Bredl, Klaus Überla, Godwin Nchinda, Klara Tenner-Racz, Ludwig Deml
Publikováno v:
Virology. 351(1):133-144
Vaccination with exogenous antigens such as recombinant viral proteins, immunodeficiency virus-derived whole inactivated virus particles, or virus-like particles (VLP) has generally failed to provide sufficient protection in animal models for AIDS. P
Autor:
Jonathan L. Heeney, Nicole Stolte, Kerstin Mätz-Rensing, Jacek Skowronski, Matthias Brenner, Christiane Stahl-Hennig, Jan Münch, Monika Franz, Michael Schindler, Frank Kirchhoff, Katarzyna Hrecka, Steffen Wildum, Dietmar Fuchs, Peter ten Haaft, Tomek Swigut
Publikováno v:
Journal of Virology. 80:4469-4481
Point mutations in SIVmac239 Nef disrupting CD4 downmodulation and enhancement of virion infectivity attenuate viral replication in acutely infected rhesus macaques, but changes selected later in infection fully restore Nef function (A. J. Iafrate et
Autor:
Young Chul Sung, Doris Wilfingseder, Heribert Stoiber, Ki Seok Park, Kwang S. Kim, Gerhard Hunsmann, Kilaus Uberla, Ulrike Sauermann, Monika Franz, Reiner Schulte, You S. Suh, So S Ahn, Christiane Stahl-Hennig
Publikováno v:
Vaccine. 26(51)
To evaluate the efficacy of a multigenic vaccine and its protective immunity in the SIVmac239 challenge model, 12 rhesus macaques were divided into two groups. The vaccine group was intramuscularly immunized with multigenic DNA and recombinant adenov
Autor:
Ki Seok Park, Gerhard Hunsmann, Monika Franz, So-Shin Ahn, You Suk Suh, Young Chul Sung, Kwang Soon Kim, Reiner Schulte, Christiane Stahl-Hennig, Nicole Stolte-Leeb, Ulrike Sauermann
Publikováno v:
Journal of medical primatology. 36(4-5)
Background Due to an ever increasing shortage of rhesus macaques ofIndian origin (InR) that have been generally used for preclinical AIDS vac-cine trials in non-human primates, demand is rising for Chinese rhesusmacaques (ChR). However, the immunogen
Autor:
Ulrike Sauermann, Gerhard Hunsmann, Jonathan L. Heeney, Nicole Stolte-Leeb, Christiane Stahl-Hennig, Stephen Norley, Monika Franz, Zahra Fagrouch
Publikováno v:
Viral immunology. 19(3)
As part of a European multicenter study designed to determine the optimal combination and order of a mixed-modality vaccine against acquired immunodeficiency syndrome, rhesus monkeys received a combination of three different vectors, all expressing t
Autor:
You S. Suh, Stephen Norley, Zahra Fagrouch, Monika Franz, Gerhard Hunsmann, Ki Seok Park, Young Chul Sung, Jonathan L. Heeney, Ulrike Sauermann, Christiane Stahl-Hennig, Doris Wilfingseder, Heribert Stoiber
Publikováno v:
Vaccine. 24(11)
In this study, we investigated the ability of a multigenic SIV DNA prime/replication-defective adenovirus serotype 5 (rAd/SIV) boost regimen to induce SIV-specific immune responses and protection against intrarectal challenge with SIVmac251 in rhesus
Autor:
Monika Franz, Wolfgang Günther, Claudia Lange, Elisabeth Kremmer, Martin Weber, Hans-Jochem Kolb
Publikováno v:
J. Immunol. 170, 5861-5868 (2003)
Adoptive immunotherapy with CTL against minor histocompatibility Ags (mHA) provides a promising way to treat leukemia relapse in allogeneic chimeras. Here we describe the in vitro generation of CTL against mHA in the dog. We tested their inhibitory e
Publikováno v:
Veterinary immunology and immunopathology. 84(1-2)
Dogs are used in preclinical transplantation models to study methods of allogeneic bone marrow transplantation (BMT). The evaluation of chimerism is of major significance for the investigation of graft-vs.-host (GvH) and host-vs.-graft (HvG) reaction