Zebrafish-Based Discovery of Antiseizure Compounds from the North Sea: Isoquinoline Alkaloids TMC-120A and TMC-120B

Autor: Daniëlle Copmans, Sara Kildgaard, Silas A. Rasmussen, Monika Ślęzak, Nina Dirkx, Michèle Partoens, Camila V. Esguerra, Alexander D. Crawford, Thomas O. Larsen, Peter A. M. de Witte

Publikováno v: Marine Drugs, Vol 17, Iss 11, p 607 (2019)

There is a high need for the development of new and improved antiseizure drugs (ASDs) to treat epilepsy. Despite the potential of marine natural products (MNPs), the EU marine biodiscovery consortium PharmaSea has made the only effort to date to perf

Externí odkaz: https://doaj.org/article/f55527d449b24d7bb5f42251a1982621

Zebrafish-based discovery of antiseizure compounds from the north sea: Isoquinoline alkaloids TMC-120A and TMC-120B

Autor: Silas Anselm Rasmussen, Sara Kildgaard, Monika Ślęzak, Camila V. Esguerra, Thomas Ostenfeld Larsen, Daniëlle Copmans, Peter de Witte, Michèle Partoens, Nina Dirkx, Alexander D. Crawford

Publikováno v: Copmans, D, Kildgaard, S, Rasmussen, S A, Ślezak, M, Dirkx, N, Partoens, M, Esguerra, C V, Crawford, A D, Larsen, T O & De Witte, P A M 2019, ' Zebrafish-based discovery of antiseizure compounds from the north sea: Isoquinoline alkaloids TMC-120A and TMC-120B ', Marine Drugs, vol. 17, no. 11, 607 . https://doi.org/10.3390/md17110607
Marine Drugs
Volume 17
Issue 11
Marine Drugs, Vol 17, Iss 11, p 607 (2019)

There is a high need for the development of new and improved antiseizure drugs (ASDs) to treat epilepsy. Despite the potential of marine natural products (MNPs), the EU marine biodiscovery consortium PharmaSea has made the only effort to date to perf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163678ca13c9692a5812464006f13c1d
https://orbit.dtu.dk/en/publications/1cba1001-99b4-4b69-92ff-cfda39e4aa59

Potential business model for a European vaccine R&D infrastructure and its estimated socio-economic impact [version 1; peer review: 1 approved, 2 approved with reservations]

Autor: Nicolas Collin, Donata Medaglini, Arjen Sloots, Maria Lawrenz, Jan A.M. Langermans, Roger Le Grand, Norbert Stockhofe-Zurwieden, Francesca Morelli, Fabrice Laurent, Frédéric Lantier, Alexandre Dobly, Dennis Christensen, Joaquim Segalés, H. M. Dockrell, Mei Mei Ho, Ole Olesen, Tom H.M. Ottenhoff, Frank A.W. Verreck, Stefan Jungbluth, Sven Arnouts, Manuel J. T. Carrondo, David Morrow, Fran Van Heuverswyn, Carlos A. Guzman, Anton Ussi, Monika Slezak, Hilde Depraetere, William Martin

Publikováno v: F1000Research, Vol 12 (2023)

Background Research infrastructures are facilities or resources that have proven fundamental for supporting scientific research and innovation. However, they are also known to be very expensive in their establishment, operation and maintenance. As by

Externí odkaz: https://doaj.org/article/9b023d85cc924663a81aea22af5b7578