Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Monika, Rafajová"'
Autor:
Miriam Zatovicova, Kvetoslava Tarábková, Anna Kaisa Parkkila, Jaromir Pastorek, Abdul Waheed, Marta Ortova Gut, Ivan Horak, Willam S Sly, Seppo Parkkila, Adriana Gibadulinova, Zuzana Biesová, V Mucha, Monika Rafajová, Silvia Pastorekova, Lýdia Jakubícková, Eliska Svastova
Publikováno v:
Journal of Immunological Methods. 282:117-134
Transmembrane carbonic anhydrase IX (CA IX) is frequently expressed in human tumours in response to hypoxia and may serve as a tumour marker and therapeutic target. So far, only a single monoclonal antibody (MAb) M75 with an epitope in the N-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::298e1ae7f9d15fcf44c7105916e8b462
https://doi.org/10.1016/j.jim.2003.08.011
https://doi.org/10.1016/j.jim.2003.08.011
Publikováno v:
Hilvo, M, Rafajová, M, Pastoreková, S, Pastorek, J & Parkkila, S 2004, ' Expression of carbonic anhydrase IX in mouse tissues ', Journal of Histochemistry and Cytochemistry, vol. 52, no. 10 . https://doi.org/10.1177/002215540405201007
Carbonic anhydrase IX (CA IX) is a unique member of the CA gene family. In contrast to the other isozymes, it has been implicated in regulation of cell proliferation, adhesion, and malignant cell invasion. In a recently described knockout mouse model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d2abbd3d2341f28c3ea357c8c9e5af
https://pubmed.ncbi.nlm.nih.gov/15385577
https://pubmed.ncbi.nlm.nih.gov/15385577
Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH
Autor:
Alessandro Cecchi, Claudiu T. Supuran, Angela Casini, Silvia Pastorekova, Monika Rafajová, Miriam Zatovicova, Eliska Svastova, Alžbeta Hulı́ková, Adriana Gibadulinova, Andrea Scozzafava, Jaromir Pastorek
Publikováno v:
FEBS letters. 577(3)
Acidic extracellular pH (pHe) is a typical attribute of a tumor microenviroment, which has an impact on cancer development and treatment outcome. It was believed to result from an accumulation of lactic acid excessively produced by glycolysis. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db697a17ab60507204edef8e1b8ebb2
https://pubmed.ncbi.nlm.nih.gov/15556624
https://pubmed.ncbi.nlm.nih.gov/15556624
Publikováno v:
International Journal of Oncology.
Hypoxia is an important factor of tumor microenvironment that significantly influences behaviour of tumor cells via activation of genes whose products are involved in adaptation to hypoxic stress, such as vascular endothelial growth factor (VEGF) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec571344381f926b5bf92ab61007f94
https://doi.org/10.3892/ijo.24.4.995
https://doi.org/10.3892/ijo.24.4.995
Autor:
Miriam, Zat'ovicová, Kvetoslava, Tarábková, Eliska, Svastová, Adriana, Gibadulinová, Vojtech, Mucha, Lýdia, Jakubícková, Zuzana, Biesová, Monika, Rafajová, Marta, Ortova Gut, Seppo, Parkkila, Anna Kaisa, Parkkila, Abdul, Waheed, Willam S, Sly, Ivan, Horak, Jaromír, Pastorek, Silvia, Pastoreková
Publikováno v:
Journal of immunological methods. 282(1-2)
Transmembrane carbonic anhydrase IX (CA IX) is frequently expressed in human tumours in response to hypoxia and may serve as a tumour marker and therapeutic target. So far, only a single monoclonal antibody (MAb) M75 with an epitope in the N-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ccbf52e346f550dae5d12b27130a650b
https://pubmed.ncbi.nlm.nih.gov/14604546
https://pubmed.ncbi.nlm.nih.gov/14604546