Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Monika, Mauermann"'
Autor:
Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani, Donglim Esther Park, Jens-Martin Hübner, Abhijit Chakraborty, Meghana Pagadala, Rosalind Bump, Sahaana Chandran, Katerina Kraft, Rocio Acuna-Hidalgo, Derek Reid, Kristin Sikkink, Monika Mauermann, Edwin F. Juarez, Anne Jenseit, James T. Robinson, Kristian W. Pajtler, Till Milde, Natalie Jäger, Petra Fiesel, Ling Morgan, Sunita Sridhar, Nicole G. Coufal, Michael Levy, Denise Malicki, Charlotte Hobbs, Stephen Kingsmore, Shareef Nahas, Matija Snuderl, John Crawford, Robert J. Wechsler-Reya, Tom Belle Davidson, Jennifer Cotter, George Michaiel, Gudrun Fleischhack, Stefan Mundlos, Anthony Schmitt, Hannah Carter, Kulandaimanuvel Antony Michealraj, Sachin A. Kumar, Michael D. Taylor, Jeremy Rich, Frank Buchholz, Jill P. Mesirov, Stefan M. Pfister, Ferhat Ay, Jesse R. Dixon, Marcel Kool, Lukas Chavez
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Ependymoma is a tumor of the brain or spinal cord. The two most common and aggressive molecular groups of ependymoma are the supratentorial ZFTA-fusion associated and the posterior fossa ependymoma group A. In both groups, tumors occur mainl
Externí odkaz:
https://doaj.org/article/7c75228f7b794031a963791639822393
Autor:
Kristian W. Pajtler, Yiju Wei, Konstantin Okonechnikov, Patricia B. G. Silva, Mikaella Vouri, Lei Zhang, Sebastian Brabetz, Laura Sieber, Melissa Gulley, Monika Mauermann, Tatjana Wedig, Norman Mack, Yuka Imamura Kawasawa, Tanvi Sharma, Marc Zuckermann, Felipe Andreiuolo, Eric Holland, Kendra Maass, Huiqin Körkel-Qu, Hai-Kun Liu, Felix Sahm, David Capper, Jens Bunt, Linda J. Richards, David T. W. Jones, Andrey Korshunov, Lukas Chavez, Peter Lichter, Mikio Hoshino, Stefan M. Pfister, Marcel Kool, Wei Li, Daisuke Kawauchi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The molecular mechanisms driving proliferation in the pediatric brain cancer epdendymoma are poorly understood. Here the authors show that a YAP1- MAMLD1 fusion drives tumor formation in mice and show that the fusion protein can collaborate with the
Externí odkaz:
https://doaj.org/article/adf1b461d84d45cc809ee416ce32b241
Autor:
Felix Rosemann, Monika Mauermann, Frank Westermann, Marcel Kool, Sjoerd van Rijn, Anke Heit-Mondrzyk, Kai-Oliver Henrich, Aylin Camgöz, Jens-Martin Hübner, Felix Schmitt-Hoffner, Umut H. Toprak, Stefan M. Pfister, Sabine Hartlieb
Publikováno v:
Journal of Clinical Oncology. 39:3217-3228
PURPOSE Clinical outcomes of patients with neuroblastoma range from spontaneous tumor regression to fatality. Hence, understanding the mechanisms that cause tumor progression is crucial for the treatment of patients. In this study, we show that FOXR2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b5c3e972e0f5b777aa27571e5f0c288
https://doi.org/10.1200/jco.20.02540
https://doi.org/10.1200/jco.20.02540
Publikováno v:
Cancer Research. 82:3885-3885
Ependymomas (EPN) are tumors of the central nervous system (CNS) that can arise in the supratentorial brain (ST-EPN), hindbrain or posterior fossa (PF-EPN), or anywhere in the spinal cord (SP-EPN), both in children and adults. Molecular profiling has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5df60345e88cd51bd4674f3bf41a07e
https://doi.org/10.1158/1538-7445.am2022-3885
https://doi.org/10.1158/1538-7445.am2022-3885
Autor:
Felix Schmitt-Hoffner, Johannes Gojo, Monika Mauermann, Katja von Hoff, Martin Sill, Andrey Korshunov, Damian Stichel, Felix Sahm, Natalie Jäger, Stefan Pfister, Marcel Kool
Publikováno v:
Cancer Research. 82:2491-2491
Using DNA methylation profiling, already in 2016 we had identified novel molecularly defined CNS tumor entities, including CNS high grade neuroepithelial tumors with MN1 alteration (HGNET-MN1), which have in the recently updated WHO classification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cba6abd5d82e978073eefc43effffdb
https://doi.org/10.1158/1538-7445.am2022-2491
https://doi.org/10.1158/1538-7445.am2022-2491
Autor:
Felix Schmitt-Hoffner, Johannes Gojo, Monika Mauermann, Katja von Hoff, Martin Sill, Damian Stichel, David Capper, Arnault Tauziede-Espariat, Pascale Varlet, Kenneth Aldape, Zied Abdullaev, Andrew M Donson, Ulrich Schüller, Matija Snuderl, Sebastian Brandner, Maria Łastowska, Joanna Trubicka, Evelina Miele, Jasper van der Lugt, Jens Bunt, Christof Kramm, Michal Zapotocky, Felix Sahm, Andrey Korshunov, Natalie Jäger, Stefan M Pfister, Marcel Kool
Publikováno v:
Neuro-Oncology. 24:i12-i13
In the recent 5th edition of the WHO classification of CNS tumors, ‘Astroblastoma, MN1 altered’ is recognized a distinct brain tumor type, occurring in children and young adults. Due to its rarity and novelty, little is known about clinical and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7e3aea95817288cc90979e01abc2aeb
https://doi.org/10.1093/neuonc/noac079.040
https://doi.org/10.1093/neuonc/noac079.040
Autor:
Hai-Kun Liu, Peter Lichter, Tatjana Wedig, Wei Li, Felix Sahm, Huiqin Körkel-Qu, Yuka Imamura Kawasawa, Jens Bunt, Kristian W. Pajtler, Eric C. Holland, Sebastian Brabetz, David Capper, Konstantin Okonechnikov, David T.W. Jones, Lei Zhang, Marc Zuckermann, Lukas Chavez, Stefan M. Pfister, Felipe Andreiuolo, Norman Mack, Daisuke Kawauchi, Yiju Wei, Marcel Kool, Laura Sieber, Linda J. Richards, Andrey Korshunov, Melissa Gulley, Mikio Hoshino, Kendra K. Maass, Monika Mauermann, Patricia Benites Goncalves da Silva, Mikaella Vouri, Tanvi Sharma
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications
Nature Communications
YAP1 fusion-positive supratentorial ependymomas predominantly occur in infants, but the molecular mechanisms of oncogenesis are unknown. Here we show YAP1-MAMLD1 fusions are sufficient to drive malignant transformation in mice, and the resulting tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2246b3de4157e2f5f986ecc728bd189
https://doaj.org/article/adf1b461d84d45cc809ee416ce32b241
https://doaj.org/article/adf1b461d84d45cc809ee416ce32b241
Publikováno v:
Neuro-Oncology. 24:i38-i38
Ependymomas (EPN) arise in the supratentorial brain (ST-EPN), posterior fossa (PF-EPN), or the spinal cord (SP-EPN), in children and adults. Molecular profiling has identified distinct subgroups in each location. Among the three molecular subgroups o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6d8b3c1edeb32e2192fb20d1f35e59c
https://doi.org/10.1093/neuonc/noac079.140
https://doi.org/10.1093/neuonc/noac079.140
Autor:
Johannes Gojo, Felix Schmitt-Hoffner, Monika Mauermann, Katja von Hoff, Martin Sill, Andrey Korshunov, Damian Stichel, David Capper, Arnault Tauziede-Espariat, Pascale Varlet, Kenneth Aldape, Zied Abdullaev, Andrew Donson, Jens Pahnke, Ulrich Schüller, Ivy Tran, Kristyn Galbraith, Matija Snuderl, Sanda Alexandrescu, Sebastian Brandner, Maria Łastowska, Evelina Miele, Jasper v Lugt, Lisethe Meijer, Jens Bunt, Christof Kramm, Jordan R Hansford, Lenka Krskova, Michal Zapotocky, Sumihito Nobusawa, David Solomon, Christine Haberler, Barbara Jones, Dominik Sturm, Felix Sahm, Natalie Jäger, Stefan M Pfister, Marcel Kool
Publikováno v:
Neuro-Oncology. 24:i50-i50
Central nervous system (CNS) tumor with BCOR internal tandem duplication (BCOR-ITD) have recently been introduced in the 5th edition of the WHO classification of CNS tumors, however, their molecular makeup and clinical characteristics remain widely e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edb16df11c90fa4c98c5858165619425
https://doi.org/10.1093/neuonc/noac079.184
https://doi.org/10.1093/neuonc/noac079.184
Autor:
Katerina Kraft, Robert J. Wechsler-Reya, Abhijit Chakraborty, Jill P. Mesirov, Derek Reid, Michael D. Taylor, Jesse R. Dixon, Frank Buchholz, Rocio Acuna-Hidalgo, Hannah Carter, Kristian W. Pajtler, Sachin Kumar, John R. Crawford, James T. Robinson, Ferhat Ay, Edwin F. Juarez, Stefan Mundlos, Kulandaimanuvel Antony Michaelraj, Konstantin Okonechnikov, Lukas Chavez, Denise M. Malicki, Nicole G. Coufal, Jens-Martin Hübner, Jeremy N. Rich, Till Milde, Matija Snuderl, Stefan M. Pfister, Donglim Esther Park, Owen Chapman, Anthony P. Schmitt, Michael J. Levy, Aylin Camgoz, Sahaana Chandran, Marcel Kool, Rosalind Bump, Shareef Nahas, Monika Mauermann, Meghana Pagadala
Ependymoma is a tumor of the brain or spinal cord. The two most common and aggressive molecular groups of ependymoma are the supratentorial RELA-fusion associated group and the posterior fossa ependymoma group A. In both groups, tumors occur mainly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdcce4993578ea10426937ff57727149
https://doi.org/10.21203/rs.3.rs-88331/v1
https://doi.org/10.21203/rs.3.rs-88331/v1
