Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Monika, Kuban"'
Autor:
Mariela Cortés-López, Laura Schulz, Mihaela Enculescu, Claudia Paret, Bea Spiekermann, Mathieu Quesnel-Vallières, Manuel Torres-Diz, Sebastian Unic, Anke Busch, Anna Orekhova, Monika Kuban, Mikhail Mesitov, Miriam M. Mulorz, Rawan Shraim, Fridolin Kielisch, Jörg Faber, Yoseph Barash, Andrei Thomas-Tikhonenko, Kathi Zarnack, Stefan Legewie, Julian König
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Multiple alternative splicing events in CD19 mRNA have been associated with resistance/relapse to CD19 CAR-T therapy in patients with B cell malignancies. Here, by combining patient data and a high-throughput mutagenesis screen, the authors identify
Externí odkaz:
https://doaj.org/article/c08d347a8dc943b8ab905da6ad76b36d
Autor:
Christoph Fritzsch, Stephan Baumgärtner, Monika Kuban, Daria Steinshorn, George Reid, Stefan Legewie
Publikováno v:
Molecular Systems Biology, Vol 14, Iss 2, Pp 1-17 (2018)
Abstract Cellular decision‐making and environmental adaptation are dependent upon a heterogeneous response of gene expression to external cues. Heterogeneity arises in transcription from random switching between transcriptionally active and inactiv
Externí odkaz:
https://doaj.org/article/52fa494a5fd24392a4ae7ba1b3868b05
Data from HER2-Affitoxin: A Potent Therapeutic Agent for the Treatment of HER2-Overexpressing Tumors
Autor:
Jacek Capala, Amir Gandjbakhche, Kimberly Shafer-Weaver, Monika Kuban, Moinuddin Hassan, Ilya Lyakhov, Rafal Zielinski
Purpose: Cancers overexpressing the HER2/neu gene are usually more aggressive and are associated with poor prognosis. Although trastuzumab has significantly improved the outcome, many tumors do not respond or acquire resistance to current therapies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ab518e472bb84d60e2b6d40ae05250
https://doi.org/10.1158/1078-0432.c.6519324.v1
https://doi.org/10.1158/1078-0432.c.6519324.v1
Autor:
Mariela, Cortés-López, Laura, Schulz, Mihaela, Enculescu, Claudia, Paret, Bea, Spiekermann, Mathieu, Quesnel-Vallières, Manuel, Torres-Diz, Sebastian, Unic, Anke, Busch, Anna, Orekhova, Monika, Kuban, Mikhail, Mesitov, Miriam M, Mulorz, Rawan, Shraim, Fridolin, Kielisch, Jörg, Faber, Yoseph, Barash, Andrei, Thomas-Tikhonenko, Kathi, Zarnack, Stefan, Legewie, Julian, König
Publikováno v:
Nature communications. 13(1)
Following CART-19 immunotherapy for B-cell acute lymphoblastic leukaemia (B-ALL), many patients relapse due to loss of the cognate CD19 epitope. Since epitope loss can be caused by aberrant CD19 exon 2 processing, we herein investigate the regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3adc23a1f7e72bbc70f381f619ca75e5
https://pubmed.ncbi.nlm.nih.gov/36138008
https://pubmed.ncbi.nlm.nih.gov/36138008
Autor:
Peter L. Choyke, Jacek Capala, Marcelino Bernardo, Ulas Bagci, Dale O. Kiesewetter, Rafal Zielinski, Aras Omer, Gabriela Kramer-Marek, Monika Kuban, Jurgen Seidel
Publikováno v:
J Nucl Med
Targeted therapies often depend on the expression of the target present in the tumor. This expression can be difficult to ascertain in widespread metastases. (18)F-FDG PET/CT, although sensitive, is nonspecific for particular tumor markers. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2280b8c78bd9eff9a989b33169fa77e
https://doi.org/10.2967/jnumed.111.100354
https://doi.org/10.2967/jnumed.111.100354
Autor:
Rafal Zielinski, Amir H. Gandjbakhche, Kimberly Shafer-Weaver, Monika Kuban, Jacek Capala, Moinuddin Hassan, Ilya G. Lyakhov
Publikováno v:
Clinical Cancer Research. 17:5071-5081
Purpose: Cancers overexpressing the HER2/neu gene are usually more aggressive and are associated with poor prognosis. Although trastuzumab has significantly improved the outcome, many tumors do not respond or acquire resistance to current therapies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a3413573f5f2f5bdbabf51371f52cf
https://doi.org/10.1158/1078-0432.ccr-10-2887
https://doi.org/10.1158/1078-0432.ccr-10-2887
Autor:
Rafal Zielinski, Monika Kuban, Ilya G. Lyakhov, Jacek Capala, Moinuddin Hassan, K Shafer-Weaver
Publikováno v:
Cancer Research. 70:P3-14
Introduction: Cancers overexpressing HER2 gene are usually described as more aggressive and are associated with poor prognosis. Although introduction of trastuzumab, a HER2-specific humanized antibody, significantly improved the outcome, there are st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce26c41435ba44573e4c464b246998d5
https://doi.org/10.1158/0008-5472.sabcs10-p3-14-23
https://doi.org/10.1158/0008-5472.sabcs10-p3-14-23
Autor:
Oleg Chertov, Gabriela Kramer-Marek, Jacek Capala, Ilya G. Lyakhov, Monika Kuban, Rafal Zielinski, Lakshman Bindu, Robert J. Fisher
Publikováno v:
ChemBioChem. 11:345-350
The human epidermal growth factor receptors, EGFR and HER2, are members of the EGFR family of cell-surface receptors/tyrosine kinases. EGFR- and HER2-positive cancers represent a more aggressive disease with greater likelihood of recurrence, poorer p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a1f8524dbe7d4bd54135c012d49880
https://doi.org/10.1002/cbic.200900532
https://doi.org/10.1002/cbic.200900532
Autor:
Monika Kuban
Publikováno v:
Finanz-Rundschau Ertragsteuerrecht. 92
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3383cb281a7cc49599ae291079829b3c
https://doi.org/10.9785/ovs-fr-2010-978
https://doi.org/10.9785/ovs-fr-2010-978
Autor:
Monika Kuban
Publikováno v:
Kommunalpolitik ISBN: 9783810011978
Kommunalpolitik ISBN: 9783810022103
Kommunalpolitik ISBN: 9783810022103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d944ab592a5ce79575d6197876ef7737
https://doi.org/10.1007/978-3-322-93826-8_22
https://doi.org/10.1007/978-3-322-93826-8_22