Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Monika, Hitzl"'
Autor:
Yisheng Cui, Edith Doppler, Mei Lu, Zheng Gang Zhang, Chunling Zhang, Li Zhang, Ruilan Zhang, Lei Wang, Monika Hitzl, Michael Chopp, Alexandra Szalad
Publikováno v:
Journal of Neuroscience Research. 88:3275-3281
Cerebrolysin is a peptide preparation mimicking the action of neurotrophic factors and has beneficial effects on neurodegenerative diseases and stroke. The present study investigated the effect of Cerebrolysin on neurogenesis in a rat model of emboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cae29624e862fbf97f9f28d287d5cfe5
https://doi.org/10.1002/jnr.22495
https://doi.org/10.1002/jnr.22495
Autor:
Anthony Adame, Edward Rockenstein, Monika Hitzl, Herbert Moessler, Chandra Inglis, Michael Mante, Eliezer Masliah, Kiren Ubhi, Leslie Crews, Edith Doppler
Publikováno v:
Acta Neuropathologica. 116:425-437
Rett syndrome is a childhood neurodevelopmental disorder caused by mutations in the gene encoding for methyl-CpG-binding protein (MeCP2). Neuropathological studies in patients with Rett syndrome and in MeCP2 mutant models have shown reduced dendritic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0185d0511b18675eab1a30ec3a33dfb0
https://doi.org/10.1007/s00401-008-0407-x
https://doi.org/10.1007/s00401-008-0407-x
Autor:
Martin F. Fromm, Georg Heinkele, Nicolas Simon, Ute Hofmann, Céline Verstuyft, Hartmut Glaeser, Monika Hitzl, Siegfried Drescher, Christian Schaefer, Thomas E. Mürdter, Oliver Burk, Michel Eichelbaum, Laurent Becquemont
Publikováno v:
Clinical Pharmacology & Therapeutics. 79:449-460
Background and Objective On the basis of in vitro studies indicating that ursodeoxycholic acid (UDCA) is a cytochrome P450 (CYP) 3A4 inducer and a pregnane X receptor activator and because the pregnane X receptor is a transcriptional regulator of mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd638350525f5dd52169ddb3cf594f81
https://doi.org/10.1016/j.clpt.2006.01.005
https://doi.org/10.1016/j.clpt.2006.01.005
Autor:
Peter Fritz, Elke Schaeffeler, Horst Halle, Martin F. Fromm, Berthold Hocher, Torsten Slowinski, Monika Hitzl, Peter Kaufmann, Michel Eichelbaum, Matthias Schwab
Publikováno v:
Pharmacogenetics. 14:309-318
The MDR1 gene product P-glycoprotein in the human placenta is important for protecting the fetus from unintended, harmful drug exposure, but also for limiting the access of therapeutic drugs to the fetus after maternal drug intake. A polymorphism in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3bd434fab5385daa4493ac8008dba81
https://doi.org/10.1097/00008571-200405000-00006
https://doi.org/10.1097/00008571-200405000-00006
Autor:
Martin F. Fromm, Matthias Schwab, Elke Schaeffeler, Siegfried Drescher, Ute Hofmann, Monika Hitzl, Ulrich Brinkmann, Michel Eichelbaum
Publikováno v:
British Journal of Clinical Pharmacology. 53:526-534
Aims The C3435T polymorphism in the human MDR1 gene is associated with lower intestinal P-glycoprotein expression, reduced protein function in peripheral blood cells and higher plasma concentrations of the P-glycoprotein substrate digoxin. Using fexo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ab70ea52b790f158cfcda3f427b6849
https://doi.org/10.1046/j.1365-2125.2002.01591.x
https://doi.org/10.1046/j.1365-2125.2002.01591.x
Autor:
Matthias Schwab, Elke Schäffeler, Eichelbaum Michel, Monika Hitzl, Heiko van der Kuip, Siegfried Drescher, Martin F. Fromm, Joachim Fischer
Publikováno v:
Pharmacogenetics. 11:293-298
P-glycoprotein (PGP) is a membrane protein which determines drug disposition in humans (e.g. digoxin). It is also expressed in various leukocyte lineages with highest expression in CD56+ natural killer cells. Recently, a polymorphism in exon 26 (C343
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38c4f02144c3efe095e6b6dcd6fffa0
https://doi.org/10.1097/00008571-200106000-00003
https://doi.org/10.1097/00008571-200106000-00003
Autor:
Chunling, Zhang, Michael, Chopp, Yisheng, Cui, Lei, Wang, Ruilan, Zhang, Li, Zhang, Mei, Lu, Alexandra, Szalad, Edith, Doppler, Monika, Hitzl, Zheng Gang, Zhang
Publikováno v:
Journal of neuroscience research. 88(15)
Cerebrolysin is a peptide preparation mimicking the action of neurotrophic factors and has beneficial effects on neurodegenerative diseases and stroke. The present study investigated the effect of Cerebrolysin on neurogenesis in a rat model of emboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a27fc69ba3a39392a600c056171ab52
https://pubmed.ncbi.nlm.nih.gov/20857512
https://pubmed.ncbi.nlm.nih.gov/20857512
Autor:
Ute I. Schwarz, Hartmut Glaeser, Wilhelm Kirch, Eberhard Kuhlisch, George K. Dresser, H. Hanso, Monika Hitzl, Richard B. Kim, Reinhard Oertel, Stephan Miehlke
Publikováno v:
Clinical pharmacology and therapeutics. 81(5)
St John's wort (SJW) is known to induce cytochrome P450 (CYP) 3A4 and P-glycoprotein through pregnane X-receptor activation. Our study evaluated the effects of long-term SJW administration on oral and intravenous pharmacokinetics of the nonmetabolize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c5051892b93e5621bbadbc17cda801
https://pubmed.ncbi.nlm.nih.gov/17392718
https://pubmed.ncbi.nlm.nih.gov/17392718
Autor:
Andrea Keil, Oliver Burk, Esther Mornhinweg, Michel Eichelbaum, Monika Hitzl, Reinhold Kerb, Kathrin Klein, Martin F. Fromm, Thomas Lang, Ulrich M. Zanger
Publikováno v:
Pharmacogenetics. 14(3)
To determine the genetic variability of multidrug resistance protein 3 (MRP3).Genomic DNA samples from 103 Caucasians were systematically screened for genetic variations to find a potential relationship with hepatic MRP3 expression. Sequencing compri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6025150b6368814a200527da267bbf05
https://pubmed.ncbi.nlm.nih.gov/15167703
https://pubmed.ncbi.nlm.nih.gov/15167703
Publikováno v:
FEBS letters. 524(1-3)
The molecular mechanisms of how alpha(1) and beta subunits of voltage-gated Ca(2+) channels interact with one another are still controversial. Here we show that despite a mutation in the beta interaction domain that has previously been shown to disru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327158dedf1d4d498d7773a837426c0d
https://pubmed.ncbi.nlm.nih.gov/12135765
https://pubmed.ncbi.nlm.nih.gov/12135765