Data from β-Catenin Up-Regulates the Expression of the Urokinase Plasminogen Activator in Human Colorectal Tumors

Autor: Andreas Jung, Thomas Kirchner, Thomas Brabletz, Ute Reuning, Moniek van Beest, Claudia Knoll, Claudia Koch, Arno Dimmler, Angela Haynl, Falk Hlubek, Stella Wassermann, Susanne Regus, Elke Hiendlmeyer

Expression of the urokinase plasminogen activator (uPA) increases during the progression of colorectal tumors from adenomas to carcinomas. The highest amounts of uPA are found at the invasion front of carcinomas, which also displays a strong expressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cfccb047511dcbb810899bac5cf2f76f
https://doi.org/10.1158/0008-5472.c.6514277.v1

Polarisation, key to good localisation

Autor: Giel Hendriks, Irene B.M. Konings, Joris H. Robben, Mark A.J. Devonald, Fiona E. Karet, Moniek van Beest, Anne K. Lagendijk, Peter M.T. Deen, Paul J.M. Savelkoul

Publikováno v: Biochimica et Biophysica Acta. Biomembranes, 1758, 1126-33
Biochimica et Biophysica Acta. Biomembranes, 1758, 8, pp. 1126-33
Biochimica et Biophysica Acta, 1758(8), 1126

Contains fulltext : 49704.pdf (Publisher’s version ) (Closed access) Polarisation of cells is crucial for vectorial transport of ions and solutes. In literature, however, proteins specifically targeted to the apical or basolateral membrane are ofte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb4b4adf224dc7edce4422f7e53212a

Activation of pre- and postsynaptic protein kinase C during tetraethylammonium-induced long-term potentiation in the CA1 field of the hippocampus

Autor: Annemarie van der Slot, Moniek van Beest, Piera Pasinelli, W.H. Gispen, Geert M.J. Ramakers, Pierre N. E. De Graan

Publikováno v: Neuroscience letters, 286(1), 53. Elsevier

Tetraethylammonium (TEA) induces a form of long-term potentiation (LTP) that is independent on N -methyl- d -aspartate (NMDA) receptor activation (LTP K ). LTP K may be a suitable chemical model to study molecular mechanisms underlying LTP. We monito

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https://doi.org/10.1016/s0304-3940(00)01081-8

Mobility of the von Hippel-Lindau tumour suppressor protein is regulated by kinesin-2

Autor: Moniek van Beest, Emile E. Voest, Laura G.M. Daenen, Rachel H. Giles, Dorus A. Mans, Martijn P. Lolkema

Publikováno v: Experimental Cell Research, 314, 6, pp. 1229-36
Experimental Cell Research, 314, 1229-36

Contains fulltext : 69428.pdf (Publisher’s version ) (Closed access) The von Hippel-Lindau tumour suppressor protein (pVHL) participates in many cellular processes including oxygen sensing, microtubule stability and primary cilia regulation. Recent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7268b5c8c1b3b14b73e2d0428b07c6f2
https://hdl.handle.net/2066/69428

Fibronectin is a hypoxia-independent target of the tumor suppressor VHL

Autor: Maartje Los, Moniek van Beest, Frank C. P. Holstege, Martijn F.B.G. Gebbink, Cristel M.J.T. Snijckers, Emile E. Voest, Hans A.R. Bluyssen, Martijn P. Lolkema, Michelle Boone, Branko Braam, Rachel H. Giles

Publikováno v: FEBS Letters, 556, 1-3, pp. 137-42
FEBS Letters, 556, 137-42

Item does not contain fulltext The von Hippel-Lindau (VHL) tumor suppressor gene regulates the extracellular matrix by controlling fibronectin deposition. To identify novel VHL target genes, we subjected mRNA from VHL-deficient RCC cells (786-0-pRC)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237dc9476b847202262a2d878752e290
https://hdl.handle.net/2066/58475