Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Monica Zamisch"'
Autor:
Yayi Gao, Monica Zamisch, Melanie Vacchio, Laura Chopp, Thomas Ciucci, Elliott L. Paine, Gaelyn C. Lyons, Jia Nie, Qi Xiao, Ekaterina Zvezdova, Paul E. Love, Charles R. Vinson, Lisa M. Jenkins, Rémy Bosselut
Publikováno v:
Sci Immunol
Although BTB–zinc finger (BTB-ZF) transcription factors control the differentiation of multiple hematopoietic and immune lineages, how they function is poorly understood. The BTB-ZF factor Thpok controls intrathymic CD4 + T cell development and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26e1b8aac03609cfc9dbed3bd3435b4
https://europepmc.org/articles/PMC9484726/
https://europepmc.org/articles/PMC9484726/
Autor:
Yayi Gao, Monica Zamisch, Melanie S Vacchio, Elliott Paine, Gaelyn Lyons, Thomas Ciucci, Laura Chopp, Qi Xiao, Charles Vinson, Lisa Jenkins, Rémy Bosselut
Publikováno v:
The Journal of Immunology. 206:108.10-108.10
T cell precursors develop into helper CD4 or cytotoxic CD8 T cells in thymus. Thpok, a BTB/POZ family transcription factor, enforces MHC II restricted thymocytes commitment to the CD4 lineage, while Runx3 protein drives MHC I restricted thymocytes to
Publikováno v:
Military Medicine. 181:195-197
INTRODUCTION Communicable diseases can be a significant burden during military operations in which missions rely on each and every team member for optimal performance. Community-acquired acute respiratory infections are particularly difficult to cont
Autor:
Marc Ehlers, Yumei Xiong, Kathryn F. Wildt, Rémy Bosselut, Linhua Tian, Monica Zamisch, I-Cheng Ho, Roland Grenningloh
Publikováno v:
The Journal of Experimental Medicine
The transcription factor Ets1 contributes to the differentiation of CD8 lineage cells in the thymus, but how it does so is not understood. In this study, we demonstrate that Ets1 is required for the proper termination of CD4 expression during the dif
Autor:
Dong-Ming Su, Ellen R. Richie, Billie A. Moore-Scott, Nancy R. Manley, Philip J. Lucas, Monica Zamisch
Publikováno v:
The Journal of Immunology. 174:60-67
Epithelial cells in the thymus produce IL-7, an essential cytokine that promotes the survival, differentiation, and proliferation of thymocytes. We identified IL-7-expressing thymic epithelial cells (TECs) throughout ontogeny and in the adult mouse t
Autor:
Fernando Benavides, Gabriel Sternik, Ellen R. Richie, Susan E. Andrew, Mónica Flores, Monica Zamisch, Julien D.F. Licchesi, Joe M. Angel, Marcia R. Campbell, Claudio J. Conti
Publikováno v:
Genes, Chromosomes and Cancer. 35:299-310
Genomic instability is believed to play a significant role in cancer development by facilitating tumor progression and tumor heterogeneity. Inter-simple sequence repeat (inter-SSR) PCR has been proved to be a fast and reproducible technique for quant
Publikováno v:
Military Medicine. 180:932-933
Noncompressible torso hemorrhage is the leading cause of potentially survivable death on the battlefield. While medical advances have decreased the rate of "died of wounds" to less than 5%, significant treatment limitations in pre-hospital care remai
Publikováno v:
SPIE Proceedings.
The repair of traumatic injuries to the central nervous system remains among the most challenging and exciting frontiers in medicine. In both traumatic brain injury and spinal cord injuries, the ultimate goals are to minimize damage and foster recove
Publikováno v:
The Journal of Immunology. 184:85.20-85.20
Thpok is a zinc-finger (ZF) transcription factor essential for CD4 T cell development. Thpok promotes CD4 T helper lineage commitment, in part through the repression of genes necessary for CD8 differentiation. A member of the BTB-ZF subclass of ZF tr
Autor:
Monica Zamisch, Linhua Tian, Roland Grenningloh, Kathryn F Wildt, Marc Ehlers, I-Cheng Ho, Remy Bosselut
Publikováno v:
The Journal of Immunology. 182:46.11-46.11
During the latest steps of thymocyte differentiation, T cell precursors that have rearranged TCRbeta and TCRalpha genes and express both CD4 and CD8 (double positive, DP) are selected into MHC II-restricted CD4 T cells, or MHC I-restricted CD8 T cell