Výsledky vyhledávání - "Monica Z Wang"

Akademický článek

Guanabenz Treatment Accelerates Disease in a Mutant SOD1 Mouse Model of ALS.

Autor: Fernando G Vieira, Qinggong Ping, Andy J Moreno, Joshua D Kidd, Kenneth Thompson, Bingbing Jiang, John M Lincecum, Monica Z Wang, Gerard S De Zutter, Valerie R Tassinari, Beth Levine, Theo Hatzipetros, Alan Gill, Steven Perrin

Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0135570 (2015)

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by loss of motor neurons. The mechanisms leading to motor neuron degeneration in ALS are unclear. However, there is evidence for involvement of endoplasmic r

Externí odkaz: https://doaj.org/article/f052d1fb3a364d89b9b51dacb83c5f26

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Primary Neurons and Differentiated NSC-34 Cells Are More Susceptible to Arginine-Rich ALS Dipeptide Repeat Protein-Associated Toxicity than Non-Differentiated NSC-34 and CHO Cells

Autor: Alan S. Premasiri, Fernando G. Vieira, Monica Z. Wang, Anna L. Gill, Beth Levine

Publikováno v: International Journal of Molecular Sciences
Volume 20
Issue 24

A repeat expansion mutation in the C9orf72 gene is the most common known genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). In this study, using multiple cell-based assay systems, we reveal both increased dipeptid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4bf48f73dc9925ce9cf8d0019e56f59
http://europepmc.org/articles/PMC6941034

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SOD1-positive aggregate accumulation in the CNS predicts slower disease progression and increased longevity in a mutant SOD1 mouse model of ALS

Autor: Cindy Gill, Theo Hatzipetros, Beth Levine, Valerie R. Tassinari, Monica Z. Wang, Joshua D. Kidd, Marcel Maier, Alan Gill, Fernando G. Vieira, Andrew Moreno, James P. Phelan, Jan Grimm, Kenneth Thompson

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)

Non-natively folded variants of superoxide dismutase 1 (SOD1) are thought to contribute to the pathogenesis of familial amyotrophic lateral sclerosis (ALS), however the relative toxicities of these variants are controversial. Here, we aimed to deciph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d68802b6d82358dbfbc6ab76dfaca8
https://pubmed.ncbi.nlm.nih.gov/31040321

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Tumor Necrosis Factor-Like Weak Inducer of Apoptosis-Induced Neurodegeneration

Autor: Moritz J. Rossner, Kyungmin Hahm, John Lincecum, Ioana Potrovita, Martin H. Maurer, Armin Schneider, Markus Schwaninger, Monica Z. Wang, Wen Zhang, Linda C. Burkly

Publikováno v: The Journal of Neuroscience. 24:8237-8244

Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor (TNF) family of cytokines. It has proangiogenic and proinflammatory propertiesin vivoand induces cell death in tumor cell lines. TWEAK effects are m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e315603b3110573cd6f576b1ada104cf
https://doi.org/10.1523/jneurosci.1089-04.2004

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Soluble Tumor Necrosis Factor Receptors Inhibit Phorbol Myristate Acetate and Cytokine-Induced HIV-1 Expression Chronically Infected U1 Cells

Autor: Charles A. Dinarello, Jonathan B. Angel, Monica Z. Wang, Eric V. Granowitz, Bradford M. Saget, Alicia Wang, Paul R. Skolnik

Publikováno v: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 11:430-437

Recombinant human tumor necrosis factor (TNF) binding protein-1 (r-h TBP-1) and recombinant human soluble dimeric TNF receptor (rhu TNFR:Fc) were used to determine the relative contributions of TNF to phorbol myristate acetate (PMA) and cytokine-indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0a6c02ff5e44434c68d65d1fc475cf
https://doi.org/10.1097/00042560-199604150-00002

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From transcriptome analysis to therapeutic anti-CD40L treatment in the SOD1 model of amyotrophic lateral sclerosis

Autor: Ricardo Sanchez, John M. Lincecum, Isarelis J Carrion, Joshua D. Kidd, Beth Levine, Andrew Moreno, Gerald S De Zutter, Kenneth Thompson, Alan Gill, Shawn M Sullivan, Fernando G. Vieira, Monica Z. Wang, Bashar M. Al‐Nakhala, Steven Perrin

Publikováno v: Nature genetics. 42(5)

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive loss of motor neurons. Using unbiased transcript profiling in an ALS mouse model, we identified a role for the co-stimulatory pathway, a key regulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1777854e2ed27f4469ed4df7386e53
https://pubmed.ncbi.nlm.nih.gov/20348957

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A novel role for tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in the development of cardiac dysfunction and failure

Publikováno v: Circulation. 119(15)

Background— Tumor necrosis factor–like weak inducer of apoptosis (TWEAK), a member of the tumor necrosis factor superfamily, is a multifunctional cytokine known to regulate cellular functions in contexts of injury and disease through its receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4ba5a33e3ca893ebf24bc7c0c874ec
https://pubmed.ncbi.nlm.nih.gov/19349318

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Guanabenz Treatment Accelerates Disease in a Mutant SOD1 Mouse Model of ALS

Autor: Valerie R. Tassinari, Theo Hatzipetros, Bingbing Jiang, John M. Lincecum, Alan Gill, Fernando G. Vieira, Monica Z. Wang, Joshua D. Kidd, Qinggong Ping, Gerard S. De Zutter, Andy J. Moreno, Steven Perrin, Kenneth Thompson, Beth Levine

Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0135570 (2015)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ba11fec7d5ae9518a56a99747b817c
https://doi.org/10.1371/journal.pone.0135570

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Tweak induces mammary epithelial branching morphogenesis

Autor: Monica Z Wang, Jennifer S. Michaelson, Timothy S. Zheng, Sandy Cho, John Lincecum, Beth Browning, Linda C. Burkly, Yen-Ming Hsu

Publikováno v: Oncogene. 24(16)

Members of the tumor necrosis factor (TNF) superfamily regulate cell survival and proliferation and have been implicated in cancer. Tweak (TNF-related weak inducer of apoptosis) has pleiotropic biological functions including proapoptotic, proangiogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf752d08fdd4803099f2f2a9ce5711f2
https://pubmed.ncbi.nlm.nih.gov/15735761

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Interactions between HIV-1 and cytomegalovirus in human osteosarcoma cells carrying both viruses

Autor: Gueh Djen Hsiung, Richard T. D'Aquila, Joan C. Kaplan, Monica Z. Wang, B R Smith, Paul R. Skolnik, M Margalith, L. J. Bechtel, Martin S. Hirsch, Daniel J. Medina

Publikováno v: AIDS research and human retroviruses. 9(6)

Cytomegalovirus (CMV) and the human immunodeficiency virus type 1 (HIV-1) may interact in the pathogenesis of AIDS. We compared CMV replication in human osteosarcoma (HOS) cells to that in HOS cells genetically engineered to contain an envelope-defic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5bcec5d00f1eb7519e144cd6ffdf598
https://pubmed.ncbi.nlm.nih.gov/8394095

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