Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Monica Viviano"'
Autor:
Silvia Salerno, Monica Viviano, Emma Baglini, Valeria Poggetti, Doralice Giorgini, Jacopo Castagnoli, Elisabetta Barresi, Sabrina Castellano, Federico Da Settimo, Sabrina Taliani
Publikováno v:
Molecules, Vol 29, Iss 17, p 4212 (2024)
The translocator protein (TSPO) is predominately localized on the outer mitochondrial membrane in steroidogenic cells. In the brain, TSPO expression, low under normal conditions, results upregulated in response to glial cell activation, that occurs i
Externí odkaz:
https://doaj.org/article/d2ddf4396b5040eaa662e86ad6c54d30
Autor:
Elisabetta Barresi, Marco Robello, Emma Baglini, Valeria Poggetti, Monica Viviano, Silvia Salerno, Federico Da Settimo, Sabrina Taliani
Publikováno v:
Pharmaceuticals, Vol 16, Iss 7, p 997 (2023)
In recent years, indolylglyoxylamide-based derivatives have received much attention due to their application in drug design and discovery, leading to the development of a wide array of compounds that have shown a variety of pharmacological activities
Externí odkaz:
https://doaj.org/article/3d5648265e164b6a94a4793759d4bbf5
Autor:
Emma Baglini, Rahul Ravichandran, Emanuela Berrino, Silvia Salerno, Elisabetta Barresi, Anna Maria Marini, Monica Viviano, Sabrina Castellano, Federico Da Settimo, Claudiu T. Supuran, Sandro Cosconati, Sabrina Taliani
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1874-1883 (2021)
A library of variously decorated N-phenyl secondary sulphonamides featuring the bicyclic tetrahydroquinazole scaffold was synthesised and biologically evaluated for their inhibitory activity against human carbonic anhydrase (hCA) I, II, IV, and IX. O
Externí odkaz:
https://doaj.org/article/88031813ab9443118c310ad8a0e3ccdb
Autor:
Alessandra Cipriano, Ciro Milite, Alessandra Feoli, Monica Viviano, Giacomo Pepe, Pietro Campiglia, Giuliana Sarno, Sarah Picaud, Satomi Imaide, Nikolai Makukhin, Panagis Filippakopoulos, Alessio Ciulli, Sabrina Castellano, Gianluca Sbardella
Publikováno v:
ChemMedChem. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b5edef4d66f5f45de556d8c894a9297
https://doi.org/10.1002/cmdc.202200528
https://doi.org/10.1002/cmdc.202200528
Autor:
Tanja Bartoschik, Alessandra Feoli, Monica Viviano, Vincenzo Pisapia, Sabrina Castellano, Gianluca Sbardella
Publikováno v:
SLAS Discovery. 26:77-87
MRG15 is a transcription factor containing the methyl-lysine reader chromodomain. Despite its involvement in different physiological and pathological states, to date the role of this protein has not been fully elucidated due to the lack of a specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adfb8355105ef4aed46573c578fd6987
https://doi.org/10.1177/2472555220949166
https://doi.org/10.1177/2472555220949166
Autor:
Claudiu T. Supuran, Anna Maria Marini, Monica Viviano, Federico Da Settimo, Sandro Cosconati, Elisabetta Barresi, Sabrina Taliani, Silvia Salerno, Sabrina Castellano, Emanuela Berrino, Emma Baglini, Rahul Ravichandran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1874-1883 (2021)
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
A library of variously decorated N-phenyl secondary sulphonamides featuring the bicyclic tetrahydroquinazole scaffold was synthesised and biologically evaluated for their inhibitory activity against human carbonic anhydrase (hCA) I, II, IV, and IX. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342dce90661ec300940c15a810da5bde
https://doaj.org/article/88031813ab9443118c310ad8a0e3ccdb
https://doaj.org/article/88031813ab9443118c310ad8a0e3ccdb
Autor:
Giulia Iannelli, Ciro Milite, Nils Marechal, Vincent Cura, Luc Bonnefond, Nathalie Troffer-Charlier, Alessandra Feoli, Donatella Rescigno, Yalong Wang, Alessandra Cipriano, Monica Viviano, Mark T. Bedford, Jean Cavarelli, Sabrina Castellano, Gianluca Sbardella
Publikováno v:
Journal of medicinal chemistry. 65(17)
Protein arginine methyltransferases (PRMTs) are important therapeutic targets, playing a crucial role in the regulation of many cellular processes and being linked to many diseases. Yet, there is still much to be understood regarding their functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ea2f58745b7c33c930c5c8dc029561
https://pubmed.ncbi.nlm.nih.gov/35482954
https://pubmed.ncbi.nlm.nih.gov/35482954
Autor:
Alessandra Cipriano, Ciro Milite, Alessandra Feoli, Monica Viviano, Giacomo Pepe, Pietro Campiglia, Giuliana Sarno, Sarah Picaud, Satomi Imaide, Nikolai Makukhin, Panagis Filippakopoulos, Alessio Ciulli, Sabrina Castellano, Gianluca Sbardella
The bromodomain and extra-terminal (BET) family of proteins includes BRD2, BRD3, BRD4, and the testis-specific protein, BRDT, each containing two N-terminal tandem bromodomain (BRD) modules. Potent and selective inhibitors targeting the two bromodoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97485ad4f5fc3bfd314a88b32c4c543
http://hdl.handle.net/11386/4803392
http://hdl.handle.net/11386/4803392
Autor:
Fabio Aricò, Monica Viviano, Giacomo Trapasso, Mattia Annatelli, Ciro Milite, Sabrina Castellano
A microwave-assisted chlorine-free direct phenol substitution is presented, which is indicated as a key green chemistry research area for pharmaceuticals manufacturers. The reaction of β-aminocarbonates (mustard carbonates) with several substituted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388dc76fdc54f652176c76d0dbde0878
http://hdl.handle.net/10278/3758226
http://hdl.handle.net/10278/3758226
Autor:
Martina Menna, Francesco Fiorentino, Biagina Marrocco, Alessia Lucidi, Stefano Tomassi, Domenica Cilli, Mauro Romanenghi, Matteo Cassandri, Silvia Pomella, Michele Pezzella, Donatella Del Bufalo, Mohammad Salik Zeya Ansari, Nevena Tomašević, Milan Mladenović, Monica Viviano, Gianluca Sbardella, Rossella Rota, Daniela Trisciuoglio, Saverio Minucci, Andrea Mattevi, Dante Rotili, Antonello Mai
LSD1 is a histone lysine demethylase proposed as therapeutic target in cancer. Chemical modifications applied at C2, C4 and/or C7 positions of the quinazoline core of the previously reported dual LSD1/G9a inhibitor 1 led to a series of non-covalent,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174de47d6b2349a453af568efe1b2572
http://hdl.handle.net/11588/895173
http://hdl.handle.net/11588/895173