Author Reply to Peer Reviews of The cIAP ubiquitin ligases sustain type 3 γδ T and innate lymphoid cells during aging to allow normal cutaneous and mucosal responses

Autor: Vasileios Bekiaris, Monica Torrellas Viñals, Maria V. Baglioni, Darshana Kadekar, Elisa Catafal Tardos, Isabel Ulmert, Rasmus Agerholm, Urs M. Mörbe, John Rizk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4645c22bb362e0dac6784641b6b88cdf
https://doi.org/10.15252/rc.2022236842

The immune checkpoint receptor associated phosphatases SHP-1 and SHP-2 are not required for γδT17 cell development, activation, or skin inflammation

Autor: John Rizk, Darshana Kadekar, Rasmus Agerholm, Monica Torrellas Viñals, Vasileios Bekiaris

Publikováno v: Kadekar, D D, Agerholm, R, Viñals, M T, Rizk, J A M B & Bekiaris, V 2020, ' The immune checkpoint receptor associated phosphatases SHP-1 and SHP-2 are not required for γδ T17 cell development, activation or skin inflammation ', European Journal of Immunology, vol. 50, no. 6, pp. 873-879 . https://doi.org/10.1002/eji.201948456

Interleukin(IL)-17 producing gamma delta (γδT17) cells are innate lymphocytes critical for anti-bacterial protection at barrier surfaces such as the skin but also highly pathogenic during inflammation. It is therefore important to understand the ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a47a3e51cb9863ecc193500b4350510
https://pubmed.ncbi.nlm.nih.gov/32092146

The neonatal microenvironment programs innate γδ T cells through the transcription factor STAT5

Autor: Richard Moriggl, Monica Torrellas Viñals, Elena M. Comelli, John Rizk, Rasmus Agerholm, Barbara Maurer, Darshana Kadekar, Vasileios Bekiaris, Amel Taibi, Tobias Suske, Heidi A. Neubauer

Publikováno v: J Clin Invest
Kadekar, D, Agerholm, R, Rizk, J, Neubauer, H A, Suske, T, Maurer, B, Viñals, M T, Comelli, E M, Taibi, A, Moriggl, R & Bekiaris, V 2020, ' The neonatal microenvironment programs innate γδ T cells through the transcription factor STAT5 ', Journal of Clinical Investigation, vol. 130, no. 5, pp. 2496-2508 . https://doi.org/10.1172/JCI131241

IL-17-producing RORγt+ γδ T cells (γδT17 cells) are innate lymphocytes that participate in type 3 immune responses during infection and inflammation. Herein, we show that γδT17 cells rapidly proliferate within neonatal lymph nodes and gut, whe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7dde5acdc79504c9be5009b19bcd9a
https://pubmed.ncbi.nlm.nih.gov/32281944