Zobrazeno 1 - 10 of 149 pro vyhledávání: '"Monica Thelestam"'
1
Akademický článek
Defects in Galactose Metabolism and Glycoconjugate Biosynthesis in a UDP-Glucose Pyrophosphorylase-Deficient Cell Line Are Reversed by Adding Galactose to the Growth Medium
Autor: Christelle Durrant, Jana I. Fuehring, Alexandra Willemetz, Dominique Chrétien, Giusy Sala, Riccardo Ghidoni, Abram Katz, Agnès Rötig, Monica Thelestam, Myriam Ermonval, Stuart E. H. Moore
Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 6, p 2028 (2020)
UDP-glucose (UDP-Glc) is synthesized by UGP2-encoded UDP-Glc pyrophosphorylase (UGP) and is required for glycoconjugate biosynthesis and galactose metabolism because it is a uridyl donor for galactose-1-P (Gal1P) uridyltransferase. Chinese hamster lu
Externí odkaz: https://doaj.org/article/3a49ba8963f84932af0d463d87c32c31
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2
Toxins Acting on the Cytoskeleton
Autor: Monica Thelestam, Roy Gross
This chapter deals with toxins which interfere with the cytoskeleton (CTSK) of mammalian cells. The toxins which have the CTSK as a common target form a group which is heterogeneous with respect to chemical properties as well as origins. Tubulin inte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c248b74ccdbd779f0683c9fa72b647c
https://doi.org/10.1201/9781003066538-6
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3
Defects in Galactose Metabolism and Glycoconjugate Biosynthesis in a UDP-Glucose Pyrophosphorylase-Deficient Cell Line Are Reversed by Adding Galactose to the Growth Medium
Autor: Giusy Sala, Riccardo Ghidoni, Monica Thelestam, Stuart E.H. Moore, Christelle Durrant, Jana I. Fuehring, Agnès Rötig, Alexandra Willemetz, Abram Katz, D Chretien, Myriam Ermonval
Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 6, p 2028 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2020, 21 (6), pp.2028. ⟨10.3390/ijms21062028⟩
Volume 21
Issue 6
International Journal of Molecular Sciences, MDPI, 2020, 21 (6), pp.2028. ⟨10.3390/ijms21062028⟩
UDP-glucose (UDP-Glc) is synthesized by UGP2-encoded UDP-Glc pyrophosphorylase (UGP) and is required for glycoconjugate biosynthesis and galactose metabolism because it is a uridyl donor for galactose-1-P (Gal1P) uridyltransferase. Chinese hamster lu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfe91ea1573ac5fc8e267238aae14a8
https://www.mdpi.com/1422-0067/21/6/2028
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4
Akademický článek
Myc is required for activation of the ATM-dependent checkpoints in response to DNA damage.
Autor: Lina Guerra, Ami Albihn, Susanna Tronnersjö, Qinzi Yan, Riccardo Guidi, Bo Stenerlöw, Torsten Sterzenbach, Christine Josenhans, James G Fox, David B Schauer, Monica Thelestam, Lars-Gunnar Larsson, Marie Henriksson, Teresa Frisan
Publikováno v: PLoS ONE, Vol 5, Iss 1, p e8924 (2010)
The MYC protein controls cellular functions such as differentiation, proliferation, and apoptosis. In response to genotoxic agents, cells overexpressing MYC undergo apoptosis. However, the MYC-regulated effectors acting upstream of the mitochondrial
Externí odkaz: https://doaj.org/article/f9d1a61ae3ac4f2fb16236f8f4b576aa
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5
Akademický článek
A bacterial cytotoxin identifies the RhoA exchange factor Net1 as a key effector in the response to DNA damage.
Autor: Lina Guerra, Heather S Carr, Agneta Richter-Dahlfors, Maria G Masucci, Monica Thelestam, Jeffrey A Frost, Teresa Frisan
Publikováno v: PLoS ONE, Vol 3, Iss 5, p e2254 (2008)
BackgroundExposure of adherent cells to DNA damaging agents, such as the bacterial cytolethal distending toxin (CDT) or ionizing radiations (IR), activates the small GTPase RhoA, which promotes the formation of actin stress fibers and delays cell dea
Externí odkaz: https://doaj.org/article/13685e220b60404b877b4cb86ec0367a
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6
A STAPHYLOCOCCAL α-TOXIN FRAGMENT
Autor: Monica Thelestam, Lennart Blomqvist
Publikováno v: Acta Pathologica Microbiologica Scandinavica Series B: Microbiology. :277-283
A fragment (alpha-13) of Staphylococcal alpha-toxin was compared with intact alpha-toxin as regards biochemical and biological properties, and the resulting information was used for mapping biologically-active regions of alpha-toxin. The alpha-13 fra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f759c7757e08de04e517f365cf9cd48
https://doi.org/10.1111/j.1699-0463.1986.tb03053.x
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7
A novel mode of translocation for cytolethal distending toxin
Autor: Teresa Frisan, Lina Guerra, Shane Massey, Ken Teter, Monica Thelestam, Kathleen N. Nemec, Suren A. Tatulian
Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1793(3):489-495
Thermal instability in the toxin catalytic subunit may be a common property of toxins that exit the endoplasmic reticulum (ER) by exploiting the mechanism of ER-associated degradation (ERAD). The Haemophilus ducreyi cytolethal distending toxin (HdCDT
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40279d8e55caa3a4dabd9b4947deb1f9
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8
Effects of Clostridium perfringens phospholipase C in mammalian cells
Autor: Monica Thelestam, Marietta Flores-Díaz, Richard W. Titball, Graeme C. Clark, Alberto Alape-Girón
Publikováno v: Anaerobe. 10:115-123
Clostridium perfringens phospholipase C (Cp-PLC), the major virulence factor in the pathogenesis of gas gangrene, is a Zn(2+) metalloenzyme with lecithinase and sphingomyelinase activities. Its structure shows an N-terminal domain containing the acti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e898021ba9825cc138d4e533f9a0f6
https://doi.org/10.1016/j.anaerobe.2003.11.002
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9
A point mutation in the UDP-glucose pyrophosphorylase gene results in decreases of UDP-glucose and inactivation of glycogen synthase
Autor: Monica Thelestam, Abram Katz, Alberto Alape-Girón, Juan-Carlos Higuita
Publikováno v: Biochemical Journal. 370:995-1001
The regulatory role of UDP-glucose in glycogen biogenesis was investigated in fibroblasts containing a point mutation in the UDP-glucose pyrophosphorylase gene and, consequently, chronically low UDP-glucose levels (Qc). Comparisons were made with cel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1977e563a16f24b757d431325c368a
https://doi.org/10.1042/bj20021320
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10
GTPases of the Rho Subfamily Are Required for Brucella abortus Internalization in Nonprofessional Phagocytes
Autor: Caterina Guzmán-Verri, Monica Thelestam, Christoph von Eichel-Streiber, Staffan Arvidson, Esteban Chaves-Olarte, Edgardo Moreno, Jean-Pierre Gorvel, Ignacio López-Goñi
Publikováno v: THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 276, No. 48, Issue of November 30, pp. 44435–44443, 2001
Repositorio UNA
Universidad Nacional de Costa Rica
instacron:UNA
Members of the genus Brucella are intracellular -Proteobacteria responsible for brucellosis, a chronic disease of humans and animals. Little is known about Brucella virulence mechanisms, but the abilities of these bacteria to invade and to survive wi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd3173187c6f5f8c2f581185ece2752
https://doi.org/10.1074/jbc.m105606200
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