Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Monica Testoni"'
Autor:
Francesco Bertoni, Jeffrey A. Toretsky, Brian Lannutti, Anastasios Stathis, Emanuele Zucca, B. Hilda Ye, Davide Genini, Monica Testoni, Ivo Kwee, Andrea Rinaldi, Andrea Cavalli, Saravana P. Selvanathan, Garrett Graham, Giulio Sartori, Valdemar Priebe, Laura Carrassa, Katti Jessen, Sara Napoli, Luciano Cascione, Chiara Tarantelli, Eugenio Gaudio, Elaine Yee Lin Chung, Filippo Spriano
YK-4-279 and TK-216 combinations. For each combination, the table shows the median Combination Index (CI) obtained after exposing cell lines to increasing concentration of two compounds at 8 x 8 concentrations of each compound (removing concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c30ef7f9a26307b66016b74d333ac1
https://doi.org/10.1158/1078-0432.22473042
https://doi.org/10.1158/1078-0432.22473042
Autor:
Francesco Bertoni, Jeffrey A. Toretsky, Brian Lannutti, Anastasios Stathis, Emanuele Zucca, B. Hilda Ye, Davide Genini, Monica Testoni, Ivo Kwee, Andrea Rinaldi, Andrea Cavalli, Saravana P. Selvanathan, Garrett Graham, Giulio Sartori, Valdemar Priebe, Laura Carrassa, Katti Jessen, Sara Napoli, Luciano Cascione, Chiara Tarantelli, Eugenio Gaudio, Elaine Yee Lin Chung, Filippo Spriano
Purpose:Transcription factors are commonly deregulated in cancer, and they have been widely considered as difficult to target due to their nonenzymatic mechanism of action. Altered expression levels of members of the ETS-transcription factors are oft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206542a8a12efab2866cc9fcd205d19b
https://doi.org/10.1158/1078-0432.c.6528405
https://doi.org/10.1158/1078-0432.c.6528405
Autor:
Francesco Bertoni, Emanuele Zucca, Esteban Cvitkovic, Giorgio Inghirami, Patrice Herait, María Eugenia Riveiro, Georg Stussi, Anastasios Stathis, Afua Adjeiwaa Mensah, Maurilio Ponzoni, Luciano Cascione, Monica Testoni, Andrea Rinaldi, Chiara Tarantelli, Elena Bernasconi, Ivo Kwee, Paola Bonetti, Eugenio Gaudio, Michela Boi
Supplemental Figures S7. Supplemental Figures S7. Effects of JQ1 and OTX015 on BRD4 binding to MYD88 promoter region in DLBCL cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f584d0947758f20e45f76197f418a7f
https://doi.org/10.1158/1078-0432.22460546
https://doi.org/10.1158/1078-0432.22460546
Autor:
Francesco Bertoni, Emanuele Zucca, Esteban Cvitkovic, Giorgio Inghirami, Patrice Herait, María Eugenia Riveiro, Georg Stussi, Anastasios Stathis, Afua Adjeiwaa Mensah, Maurilio Ponzoni, Luciano Cascione, Monica Testoni, Andrea Rinaldi, Chiara Tarantelli, Elena Bernasconi, Ivo Kwee, Paola Bonetti, Eugenio Gaudio, Michela Boi
Purpose: In cancer cells, the epigenome is often deregulated, and inhibition of the bromodomain and extra-terminal (BET) family of bromodomain-containing proteins is a novel epigenetic therapeutic approach. Preliminary results of an ongoing phase I t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28078890d5a2b92bf5846c8245fb3bff
https://doi.org/10.1158/1078-0432.c.6524528.v1
https://doi.org/10.1158/1078-0432.c.6524528.v1
Autor:
Francesco Bertoni, Emanuele Zucca, Esteban Cvitkovic, Giorgio Inghirami, Patrice Herait, María Eugenia Riveiro, Georg Stussi, Anastasios Stathis, Afua Adjeiwaa Mensah, Maurilio Ponzoni, Luciano Cascione, Monica Testoni, Andrea Rinaldi, Chiara Tarantelli, Elena Bernasconi, Ivo Kwee, Paola Bonetti, Eugenio Gaudio, Michela Boi
Supplemental Figures S1-2. Supplemental Figures S1: effects of OTX015 on cell cycle and cell growth in DLBCL cell lines. Supplemental Figures S2: effects of OTX015 on apoptosis in DLBCL cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e991a4ce4dd0501e46077c8b6190a9c
https://doi.org/10.1158/1078-0432.22460558.v1
https://doi.org/10.1158/1078-0432.22460558.v1
Autor:
Francesco Bertoni, Emanuele Zucca, Esteban Cvitkovic, Giorgio Inghirami, Patrice Herait, María Eugenia Riveiro, Georg Stussi, Anastasios Stathis, Afua Adjeiwaa Mensah, Maurilio Ponzoni, Luciano Cascione, Monica Testoni, Andrea Rinaldi, Chiara Tarantelli, Elena Bernasconi, Ivo Kwee, Paola Bonetti, Eugenio Gaudio, Michela Boi
Supplemental Table S4: List of gene-sets associated with the sensitivity to OTX015.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c881e3b21da0c9a242fd76d59dd338
https://doi.org/10.1158/1078-0432.22460537.v1
https://doi.org/10.1158/1078-0432.22460537.v1
Autor:
Francesco Bertoni, Emanuele Zucca, Esteban Cvitkovic, Giorgio Inghirami, Patrice Herait, María Eugenia Riveiro, Georg Stussi, Anastasios Stathis, Afua Adjeiwaa Mensah, Maurilio Ponzoni, Luciano Cascione, Monica Testoni, Andrea Rinaldi, Chiara Tarantelli, Elena Bernasconi, Ivo Kwee, Paola Bonetti, Eugenio Gaudio, Michela Boi
Supplemental Figures S3-5. Supplemental Figures S3: the gene expression changes induced by OTX015 in DLBCL cell lines. Supplemental Figures S4: network of genes affected by OTX015. Supplemental Figures S5: similar biologic effects of OTX015 and JQ1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711b57482f5ea5c8b1b2d704aaaeb06d
https://doi.org/10.1158/1078-0432.22460552
https://doi.org/10.1158/1078-0432.22460552
Autor:
Cardozo, Mônica Testoni, de Conti, Aline, Ong, Thomas Prates, Scolastici, Clarissa, Purgatto, Eduardo, Horst, Maria Aderuza, Bassoli, Bruna Kempfer, Moreno, Fernando Salvador
Publikováno v:
In The Journal of Nutritional Biochemistry 2011 22(2):130-135
Autor:
Ivo Kwee, Laura Carrassa, Monica Testoni, Katti Jessen, B. Hilda Ye, Emanuele Zucca, Filippo Spriano, Davide Genini, Valdemar Priebe, Chiara Tarantelli, Giulio Sartori, Brian J. Lannutti, Saravana P. Selvanathan, Jeffrey A. Toretsky, Sara Napoli, Andrea Cavalli, Elaine Yee Lin Chung, Andrea Rinaldi, Anastasios Stathis, Francesco Bertoni, Eugenio Gaudio, Garrett T. Graham, Luciano Cascione
Publikováno v:
Clinical Cancer Research. 25:5167-5176
Purpose: Transcription factors are commonly deregulated in cancer, and they have been widely considered as difficult to target due to their nonenzymatic mechanism of action. Altered expression levels of members of the ETS-transcription factors are of
Autor:
Santiago Montes-Moreno, Monica Testoni, Timothy C. Greiner, Luca Baldini, Gianluca Gaidano, Andrés J.M. Ferreri, Annalisa Chiappella, Ivo Kwee, Wing C. Chan, Francesco Bertoni, Julie M. Vose, Emanuele Zucca, Michael Mian
Publikováno v:
British Journal of Haematology. 155:274-277