Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Monica S Guo"'
Autor:
Alexandria J Cockrell, Jeffrey J Lange, Christopher Wood, Mark Mattingly, Scott M McCroskey, William D Bradford, Juliana Conkright-Fincham, Lauren Weems, Monica S Guo, Jennifer L Gerton
Publikováno v:
PLoS Genetics, Vol 20, Iss 7, p e1011331 (2024)
Nucleolar morphology is a well-established indicator of ribosome biogenesis activity that has served as the foundation of many screens investigating ribosome production. Missing from this field of study is a broad-scale investigation of the regulatio
Externí odkaz:
https://doaj.org/article/1b5df90b2dd94b169054ebf987bcf056
Autor:
Edward A Arnold, Robin J Kaai, Katie Leung, Mia R Brinkley, Laurel E Kelnhofer-Millevolte, Monica S Guo, Daphne C Avgousti
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011633 (2023)
Viruses hijack host proteins to promote infection and dampen host defenses. Adenovirus encodes the multifunctional protein VII that serves both to compact viral genomes inside the virion and disrupt host chromatin. Protein VII binds the abundant nucl
Externí odkaz:
https://doaj.org/article/b738456993034100ae2a4948ee61ffce
Publikováno v:
eLife, Vol 10 (2021)
Supercoiling impacts DNA replication, transcription, protein binding to DNA, and the three-dimensional organization of chromosomes. However, there are currently no methods to directly interrogate or map positive supercoils, so their distribution in g
Externí odkaz:
https://doaj.org/article/b2cec7f1e03c4f74a4e36b60201f5103
Autor:
Thuy-Lan V Lite, Robert A Grant, Isabel Nocedal, Megan L Littlehale, Monica S Guo, Michael T Laub
Publikováno v:
eLife, Vol 9 (2020)
Protein-protein interaction specificity is often encoded at the primary sequence level. However, the contributions of individual residues to specificity are usually poorly understood and often obscured by mutational robustness, sequence degeneracy, a
Externí odkaz:
https://doaj.org/article/44387ca2d4864218b45b55e20d7105f2
Publikováno v:
eLife, Vol 6 (2017)
Most bacteria are in fierce competition with other species for limited nutrients. Some bacteria can kill nearby cells by secreting bacteriocins, a diverse group of proteinaceous antimicrobials. However, bacteriocins are typically freely diffusible, a
Externí odkaz:
https://doaj.org/article/5f1b9bdf4b96497ebd37960558571b17
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT CRISPR interference (CRISPRi) is a powerful new tool used in different organisms that provides a fast, specific, and reliable way to knock down gene expression. Caulobacter crescentus is a well-studied model bacterium, and although a variety
Externí odkaz:
https://doaj.org/article/cde1b2890ea147749615aedc5ece184e
Autor:
Edward A. Arnold, Robin J. Kaai, Katie Leung, Mia R. Brinkley, Laurel E Kelnhofer-Millevolte, Monica S. Guo, Daphne C. Avgousti
Publikováno v:
bioRxiv
Viruses hijack host proteins to promote infection and dampen host defenses. Adenovirus encodes the multifunctional protein VII that serves both to compact viral genomes inside the virion and disrupt host chromatin. Protein VII binds the abundant nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e89c6cc356d961e1ea47e3f2e6e2713
https://doi.org/10.1101/2023.04.17.537247
https://doi.org/10.1101/2023.04.17.537247
This study aims to explore whether and how positive and negative supercoiling contribute to the three-dimensional (3D) spatial organization of the bacterial genome. We used recently published GapR ChIP-seq and Topo-seq data, which marks positive and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc8ce39a4b33309d714172c5b5a843d
https://doi.org/10.1101/2022.12.30.522362
https://doi.org/10.1101/2022.12.30.522362
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Supercoiling impacts DNA replication, transcription, protein binding to DNA, and the three-dimensional organization of chromosomes. However, there are currently no methods to directly interrogate or map positive supercoils, so their distribution in g