Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Monica Pata"'
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104160- (2022)
Summary: Ostm1 mutations cause the severe form of osteopetrosis with bone marrow deficiency in humans and mice, yet a role in T cell ontogeny remains to be determined. Herein, we show that thymi of the Ostm1-null mice (gl/gl) from P8-to-P15 become ma
Externí odkaz:
https://doaj.org/article/1a9c1501204b43fb9a11c6fe232e6d5e
Publikováno v:
iScience. 25(4)
Publikováno v:
Academia y Virtualidad, Vol 17, Iss 2 (2024)
This qualitative research study aimed to describe the transition from face-to-face to virtual education, in order to understand, as teachers, the personal and academic life of students before and during the pandemic. This descriptive study was conduc
Externí odkaz:
https://doaj.org/article/a0b9ab46130441beb2b4919ef5845829
Publikováno v:
Genesis (New York, N.Y. : 2000)REFERENCES. 59(3)
Mutations in the osteopetrotic transmembrane protein 1 (Ostm1) gene are responsible for the most severe form of autosomal recessive osteopetrosis both in humans and in the gray lethal (gl/gl) mouse. This defect leads to increased bone mass with bone
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 5600, p 5600 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 5600, p 5600 (2020)
The maintenance of bone mass is a dynamic process that requires a strict balance between bone formation and resorption. Bone formation is controlled by osteoblasts, while osteoclasts are responsible for resorption of the bone matrix. The opposite fun
The osteoclast has been and still is the subject of many investgations to understand its tight regulation as a cell whose primary role is to destroy bone tissue. These large mature post-mitotic cells are difficult to isolate and manipulate since they
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04f2de51b88f01adbfdfc36e9da2e665
https://doi.org/10.1016/b978-0-12-801238-3.11169-9
https://doi.org/10.1016/b978-0-12-801238-3.11169-9
Autor:
Monica Pata, Jean Vacher
Publikováno v:
Journal of Bone and Mineral Research. 33:888-898
Ostm1 mutations are responsible for the most severe form of osteopetrosis in human and mice. To gain insight into Ostm1 cellular functions, we engineered a conditional in-frame deletion of the Ostm1 transmembrane domain and generated the first Ostm1
Publikováno v:
World Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 9, Iss 2, Pp 183-188 (2023)
Abstract Objectives Resection of the middle turbinate (MT) during endoscopic sinus surgery (ESS) has been a controversial topic among otolaryngologists for many years. Some studies advocate resection and have shown improved outcomes postoperatively,
Externí odkaz:
https://doaj.org/article/9dd7e561be204167bd555c5b3340eccd
Autor:
Monica, Pata, Jean, Vacher
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 33(5)
Ostm1 mutations are responsible for the most severe form of osteopetrosis in human and mice. To gain insight into Ostm1 cellular functions, we engineered a conditional in-frame deletion of the Ostm1 transmembrane domain and generated the first Ostm1
Autor:
Subramanya N.M. Pandruvada, Jean Vacher, Monica Pata, Suzanne Benjannet, Nabil G. Seidah, Claude Lazure, Janie Beauregard
In humans and in mice, mutations in the Ostm1 gene cause the most severe form of osteopetrosis, a major bone disease, and neuronal degeneration, both of which are associated with early death. To gain insight into Ostm1 function, we first investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e0161d491b40fb9612b1b6d6c021b7
https://europepmc.org/articles/PMC4719428/
https://europepmc.org/articles/PMC4719428/