Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Monica P Colaiácovo"'
Autor:
Marina Martinez-Garcia, Pedro Robles Naharro, Marnie W Skinner, Kerstin A Baran, Laura I Lascarez-Lagunas, Saravanapriah Nadarajan, Nara Shin, Carlos G Silva-García, Takamune T Saito, Sara Beese-Sims, Brianna N Diaz-Pacheco, Elizaveta Berson, Ana B Castañer, Sarai Pacheco, Enrique Martinez-Perez, Philip W Jordan, Monica P Colaiácovo
Publikováno v:
PLoS Genetics, Vol 19, Iss 2, p e1010666 (2023)
Chromosome movements and licensing of synapsis must be tightly regulated during early meiosis to ensure accurate chromosome segregation and avoid aneuploidy, although how these steps are coordinated is not fully understood. Here we show that GRAS-1,
Externí odkaz:
https://doaj.org/article/256d8d7b5f334b59810c1d4d8aae4a05
Autor:
Xiaojuan Zhang, Sisi Tian, Sara E Beese-Sims, Jingjie Chen, Nara Shin, Monica P Colaiácovo, Hyun-Min Kim
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009715 (2021)
Histone methylation is dynamically regulated to shape the epigenome and adjust central nuclear processes including transcription, cell cycle control and DNA repair. Lysine-specific histone demethylase 2 (LSD2) has been implicated in multiple types of
Externí odkaz:
https://doaj.org/article/2881f9edb3744b8f8faa11a7833c1199
Autor:
Simon Yuan Wang, Hui Mao, Hiroki Shibuya, Satoru Uzawa, Zach Klapholz O'Brown, Sage Wesenberg, Nara Shin, Takamune T Saito, Jinmin Gao, Barbara J Meyer, Monica P Colaiácovo, Eric Lieberman Greer
Publikováno v:
PLoS Genetics, Vol 15, Iss 7, p e1008252 (2019)
The biological roles of nucleic acid methylation, other than at the C5-position of cytosines in CpG dinucleotides, are still not well understood. Here, we report genetic evidence for a critical role for the putative DNA demethylase NMAD-1 in regulati
Externí odkaz:
https://doaj.org/article/4f79ad7a2bb94a589ae6c472b54c39ff
Publikováno v:
PLoS Genetics, Vol 15, Iss 2, p e1007975 (2019)
Chemicals that are highly prevalent in our environment, such as phthalates and pesticides, have been linked to problems associated with reproductive health. However, rapid assessment of their impact on reproductive health and understanding how they c
Externí odkaz:
https://doaj.org/article/8ea3c1cbab8a447db12ce7fb2cdccd3c
Autor:
Saravanapriah Nadarajan, Talley J Lambert, Elisabeth Altendorfer, Jinmin Gao, Michael D Blower, Jennifer C Waters, Monica P Colaiácovo
Publikováno v:
eLife, Vol 6 (2017)
The synaptonemal complex (SC) is an ultrastructurally conserved proteinaceous structure that holds homologous chromosomes together and is required for the stabilization of pairing interactions and the completion of crossover (CO) formation between ho
Externí odkaz:
https://doaj.org/article/a687ce32370b43c2aa5ffeafbfcc3c61
Autor:
Tasha K Mendes, Stevan Novakovic, Greta Raymant, Sonja E Bertram, Reza Esmaillie, Saravanapriah Nadarajan, Bert Breugelmans, Andreas Hofmann, Robin B Gasser, Monica P Colaiácovo, Peter R Boag
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156191 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0117444.].
Externí odkaz:
https://doaj.org/article/779d9c0402df44d284b348ee50c79971
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005029 (2015)
The formation of DNA double-strand breaks (DSBs) must take place during meiosis to ensure the formation of crossovers, which are required for accurate chromosome segregation, therefore avoiding aneuploidy. However, DSB formation must be tightly regul
Externí odkaz:
https://doaj.org/article/9048d7263f834f10aa449ef54421e97d
Autor:
Tasha K Mendes, Stevan Novakovic, Greta Raymant, Sonja E Bertram, Reza Esmaillie, Saravanapriah Nadarajan, Bert Breugelmans, Andreas Hofmann, Robin B Gasser, Monica P Colaiácovo, Peter R Boag
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117444 (2015)
RIO protein kinases (RIOKs) are a relatively conserved family of enzymes implicated in cell cycle control and ribosomal RNA processing. Despite their functional importance, they remain a poorly understood group of kinases in multicellular organisms.
Externí odkaz:
https://doaj.org/article/5ca7018e238a4e25baaba16b94d9db9f
Autor:
Hyun-Min Kim, Monica P Colaiácovo
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004723 (2014)
Germline mutations in DNA repair genes are linked to tumor progression. Furthermore, failure in either activating a DNA damage checkpoint or repairing programmed meiotic double-strand breaks (DSBs) can impair chromosome segregation. Therefore, unders
Externí odkaz:
https://doaj.org/article/2967afb4e1e34d71b9453d4d247a4a6a
Publikováno v:
PLoS Genetics, Vol 9, Iss 7, p e1003586 (2013)
The number and distribution of crossover events are tightly regulated at prophase of meiosis I. The resolution of Holliday junctions by structure-specific endonucleases, including MUS-81, SLX-1, XPF-1 and GEN-1, is one of the main mechanisms proposed
Externí odkaz:
https://doaj.org/article/410d0cb97f8449a696e96661b71d6468