Výsledky vyhledávání - "Monica Olague-Marchan"

Autoimmune Responses in Patients with Linear IgA Bullous Dermatosis: Both Autoantibodies and T Lymphocytes Recognize the NC16A Domain of the BP180 Molecule

Autor: Janet A. Fairley, Detlef Zillikens, Monica Olague-Marchan, Chang-Ling Fu, George J. Giudice, Mary K. Hacker, Mong-Shang Lin

Publikováno v: Clinical Immunology. 102:310-319

Linear IgA bullous disease (LABD) is an autoimmune skin disease characterized by subepidermal blisters and IgA autoantibodies directed against the epidermal basement membrane zone (BMZ) of the skin. Various antigens have been identified as targets of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5716a3eeb6403c36d641e212206db0a3
https://doi.org/10.1006/clim.2001.5177

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A disease-associated glycine substitution in BP180 (type XVII collagen) leads to a local destabilization of the major collagen triple helix

Autor: Sally S. Twining, Mary K. Hacker, George J. Giudice, Monica Olague-Marchan, Luis A. Diaz, John A. McGrath

Publikováno v: Matrix Biology. 19:223-233

BP180 is a homotrimeric transmembrane protein with a carboxy-terminal ectodomain that forms an interrupted collagen triple helix. Null type mutations in the BP180 gene produce a recessive subepidermal blistering disease, non-Herlitz junctional epider

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b0168c92e4b414a1ebeaaf19088595
https://doi.org/10.1016/s0945-053x(00)00070-6

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Molecular Mapping of the Major Epitopes of BP180 Recognized by Herpes Gestationis Autoantibodies

Autor: Mong Shang Lin, George J. Giudice, K E Harman, Luis A. Diaz, Mary K. Hacker, Chang Ling Fu, Balbir S. Bhogal, Martin M. Black, Manish Gharia, Monica Olague-Marchan

Publikováno v: Clinical Immunology. 92:285-292

Herpes gestationis (HG) is an autoantibody-mediated subepidermal bullous dermatosis associated with pregnancy. The primary target of HG autoantibodies is BP180, a 180-kDa hemidesmosomal glycoprotein. We previously showed that autoantibodies and autoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20b7a72f0cc28414a783aaf759a3071
https://doi.org/10.1006/clim.1999.4756

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Tight Clustering of Extracellular BP180 Epitopes Recognized by Bullous Pemphigoid Autoantibodies

Autor: Monica Olague-Marchan, Detlef Zillikens, George J. Giudice, Luis A. Diaz, Zhi Liu, Shawn D. Balding, Pamela A. Rose

Publikováno v: Journal of Investigative Dermatology. 109(4):573-579

Bullous pemphigoid is a blistering skin disease associated with autoantibodies against the BP180 antigen, a transmembrane component of the hemidesmosome. Anti-BP180 antibodies have been demonstrated to be pathogenic in a passive transfer mouse model.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536d5946403061584576810941c14eaa

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The NC16A domain of collagen XVII plays a role in triple helix assembly and stability

Autor: George J. Giudice, Francoise Van den Bergh, Monica Olague-Marchan, Chang-Ling Fu

Publikováno v: Biochemical and biophysical research communications. 350(4)

Collagen XVII/BP180 is a transmembrane constituent of the epidermal anchoring complex. To study the role of its non-collagenous linker domain, NC16A, in protein assembly and stability, we analyzed the following recombinant proteins: the collagen XVII

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c92f8a715aadff21fdcd579478023e7
https://pubmed.ncbi.nlm.nih.gov/17045967

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Epitopes targeted by bullous pemphigoid T lymphocytes and autoantibodies map to the same sites on the bullous pemphigoid 180 ectodomain

Autor: Mong Shang Lin, George J. Giudice, AM Lazaro, Luis A. Diaz, Peter Stastny, Chang Ling Fu, Monica Olague-Marchan

Publikováno v: The Journal of investigative dermatology. 115(6)

Bullous pemphigoid is a blistering skin disease characterized by autoantibodies directed against the NC16A domain of bullous pemphigoid 180 (collagen XVII), a transmembrane protein of epidermal basal cells. Passive transfer studies in mice have shown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f781ed32955860c6801dcf61a396da
https://pubmed.ncbi.nlm.nih.gov/11121125

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Transplacental passage of maternal pemphigus foliaceus autoantibodies induces neonatal pemphigus

Autor: Luis A. Diaz, Argelia López-Swiderski, Esperanza Avalos-Díaz, Rafael Herrera-Esparza, Monica Olague-Marchan

Publikováno v: Journal of the American Academy of Dermatology. 43(6)

The association of maternal pemphigus foliaceus (PF) with neonatal PF is rare and may be secondary to transplacental passage of PF autoantibodies. We describe a 25-year-old patient with PF who was delivered of two consecutive babies, one with classic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644936ac21d4b7248039d7eae08524b3
https://pubmed.ncbi.nlm.nih.gov/11100038

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Corneal Activation of Prothrombin to Form Thrombin, Independent of Vascular Injury

Autor: Monica Olague-Marchan, Aidee Ayala, Debra J. Warejcka, Sally S. Twining

Publikováno v: Investigative Opthalmology & Visual Science. 48:134

PURPOSE. Two major functions of thrombin observed in the cornea are activation of thrombin-sensitive, proteinase-activated receptors and cleavage of fibrinogen to fibrin. The purpose of this study was to determine whether the normal human cornea itse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a82f7efd4be3e0cb2eccaac1040ead
https://doi.org/10.1167/iovs.06-0339

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