Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Monica Nunez Lopez"'
Generation of endogenously tagged E-cadherin cells using gene editing via non-homologous end joining
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102305- (2023)
Summary: We provide a protocol using non-homologous end joining to integrate an oligonucleotide sequence of a fluorescence protein at the CDH1 locus encoding for the epithelial glycoprotein E-cadherin. We describe steps for implementing the CRISPR-Ca
Externí odkaz:
https://doaj.org/article/afdcb0e1a13442128cdfeef619702a44
Autor:
Viola Heinzelmann-Schwarz, Claudia Lengerke, Nicolle H. Packer, Monica Nunez Lopez, Andreas Schötzau, Andre Fedier, Natalie Rimmer, Yen-Lin Huang, Arun V. Everest-Dass, Reto S. Kohler, Ching-Yeu Liang, Martina Konantz, Shahidul Alam, Francis Jacob
This file contains: Supplementary material & methods Supplementary Figure S1 Globoside GSL synthesizing glycosyltransferases show elevated gene expression in epithelial tissue samples. Supplementary Figure S2 EMT marker gene expression in 47 ovarian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6baf82fed250df71f8d901de608d34e6
https://doi.org/10.1158/0008-5472.22417022.v1
https://doi.org/10.1158/0008-5472.22417022.v1
Autor:
Alessandra Tozzi, Muriel Disler, Ricardo Coelho, Flavio Lombardo, Andre Fedier, Monica Nunez Lopez, Florian Freuler, Francis Jacob, Viola Heinzelmann-Schwarz
Publikováno v:
Translational research/biomarkers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36fe7dfd2f2494739ec59a1b083befaa
https://doi.org/10.1136/ijgc-2022-esgo.892
https://doi.org/10.1136/ijgc-2022-esgo.892
Autor:
Kathrin B. Labrosse, Flavio C. Lombardo, Natalie Rimmer, Mónica Núñez López, André Fedier, Viola Heinzelmann-Schwarz, Ricardo Coelho, Francis Jacob
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103274- (2024)
Summary: Three-dimensional (3D) ex vivo cultures allow the study of cancer progression and drug resistance mechanisms. Here, we present a protocol for measuring on-target drug sensitivity in a scaffold-free 3D culture system through quantification of
Externí odkaz:
https://doaj.org/article/7878e94092734d8e99c5e69881ee4ebf
Autor:
Ricardo Coelho, Alessandra Tozzi, Muriel Disler, Flavio Lombardo, André Fedier, Mónica Núñez López, Florian Freuler, Francis Jacob, Viola Heinzelmann-Schwarz
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-13 (2022)
Abstract PARP inhibitors (PARPi) have revolutionized the therapeutic landscape of epithelial ovarian cancer (EOC) treatment with outstanding benefits in regard to progression-free survival, especially in patients either carrying BRCA1/2 mutations or
Externí odkaz:
https://doaj.org/article/dc5ab75700d94ee09c33c23ff0a4a4ac
Autor:
Yen-Lin Huang, Ching-Yeu Liang, Danilo Ritz, Ricardo Coelho, Dedy Septiadi, Manuela Estermann, Cécile Cumin, Natalie Rimmer, Andreas Schötzau, Mónica Núñez López, André Fedier, Martina Konantz, Tatjana Vlajnic, Diego Calabrese, Claudia Lengerke, Leonor David, Barbara Rothen-Rutishauser, Francis Jacob, Viola Heinzelmann-Schwarz
Publikováno v:
eLife, Vol 9 (2020)
The extracellular matrix (ECM) plays critical roles in tumor progression and metastasis. However, the contribution of ECM proteins to early metastatic onset in the peritoneal cavity remains unexplored. Here, we suggest a new route of metastasis throu
Externí odkaz:
https://doaj.org/article/1d428aa47c2f4db9a039680fd8b80d54