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pro vyhledávání: '"Monica N Morgan"'
Autor:
Samantha S. Zaiter, Nalin Kataria, Bernadette Kerr, Monica N Morgan, Shelli R. McAlpine, Chloe-Anne Martinez, Kristina M. Cook
Publikováno v:
Cellular Physiology and Biochemistry, Vol 53, Iss 3, Pp 480-495 (2019)
Background/aims Hypoxia Inducible Factor-1α (HIF-1α) is involved in cancer progression and is stabilized by the chaperone HSP90 (Heat Shock Protein 90), preventing degradation. Previously identified HSP90 inhibitors bind to the N-terminal pocket of
Autor:
Monica N Morgan, Chloe-Anne Martinez, Sapir Dvuchbabny, Peter A. Cistulli, Kristina M. Cook, Bernadette Kerr
Publikováno v:
Clocks & Sleep
Circadian rhythms regulate many physiological and behavioral processes, including sleep, metabolism and cell division, which have a 24-h oscillation pattern. Rhythmicity is generated by a transcriptional–translational feedback loop in individual ce