Extracellular vesicles from recombinant cell factories improve the activity and efficacy of enzymes defective in lysosomal storage disorders

Autor: Rosa Mendoza, Zamira V. Díaz-Riascos, Sandra Mancilla, Lorenzo Albertazzi, Natalia García-Aranda, Ana Boullosa, Antonio Villaverde, Monica Mandaña, Patricia González, Ibane Abasolo, Anna Rosell, Guillem Pintos-Morell, José Luis Corchero, Josefina Casas, Simó Schwartz, Alba Grayston, Joaquin Seras-Franzoso, Roger Riera, Elena García-Fruitós, Marc Moltó-Abad

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Journal of Extracellular Vesicles, Vol 10, Iss 5, Pp n/a-n/a (2021)
Scientia
Journal of Extracellular Vesicles
Digital.CSIC. Repositorio Institucional del CSIC
instname

In the present study the use of extracellular vesicles (EVs) as vehicles for therapeutic enzymes in lysosomal storage disorders was explored. EVs were isolated from mammalian cells overexpressing alpha‐galactosidase A (GLA) or N‐sulfoglucosamine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702cb6a58bfe0e56afbde20b3d5154b2
http://hdl.handle.net/10261/234882

Extracellular vesicles from recombinant cell factories improve the activity and efficacy of enzymes defective in lysosomal storage disorders

Autor: Joaquin Seras‐Franzoso, Zamira V. Díaz‐Riascos, José Luis Corchero, Patricia González, Natalia García‐Aranda, Mònica Mandaña, Roger Riera, Ana Boullosa, Sandra Mancilla, Alba Grayston, Marc Moltó‐Abad, Elena Garcia‐Fruitós, Rosa Mendoza, Guillem Pintos‐Morell, Lorenzo Albertazzi, Anna Rosell, Josefina Casas, Antonio Villaverde, Simó Schwartz Jr, Ibane Abasolo

Publikováno v: Journal of Extracellular Vesicles, Vol 10, Iss 5, Pp n/a-n/a (2021)

Abstract In the present study the use of extracellular vesicles (EVs) as vehicles for therapeutic enzymes in lysosomal storage disorders was explored. EVs were isolated from mammalian cells overexpressing alpha‐galactosidase A (GLA) or N‐sulfoglu

Externí odkaz: https://doaj.org/article/017c9b6b0e7544dbad5fbbce1391a4b6